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201.
Fluoxetine is a selective serotonin reuptake inhibitor, commonly used for the treatment of a variety of psychopathological conditions. As such, fluoxetine may be expected to appear in clinical and forensic cases. Dermestes maculatus De Geer (Coleoptera: Dermestidae) has been recognized as a relevant component of the insect fauna associated with decomposing human and animal remains. Experiments were conducted to study the effect of fluoxetine on developing D. maculatus using two‐drug administration models: a non‐living animal model (pork muscle) and a living one (Sus scrofa L. pigs). We assessed the duration of immature stages and total life cycle, as well as morphological parameters (body length, cephalic width, and weight). The effect of fluoxetine was studied at an overdose concentration: In the non‐living animal model the drug was mixed with macerated pork muscle (2000 mg/kg) and in the living animal model, pigs were given the drug orally (833 mg/kg). A control was used for each model. Daily observations were performed from the beginning to the end of the experiments. GC‐MS was used for drug detection and quantification. There were no statistically significant differences in the duration of immature stages, life cycle, larval mortality, morphological parameters, or sex ratio, between treatment and control, regardless of the drug administration model. Given that fluoxetine had no detectable effect on the development of D. maculatus, detection of this drug in forensic situations would not compromise the accuracy of PMI estimations.  相似文献   
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In 1893, Prime Minister Gladstone introduced the second Irish home rule bill in parliament. The bill broke with tradition in Britain and the empire, as it included provisions from the bill of rights of the United States. Its significance was clear at the time: it was debated for nine days in the committee stage and, with one minor amendment, it remained part of the bill that passed the Commons. However, the bill was defeated in the Lords and, at least in the United Kingdom, bills of rights were dismissed as unnecessary or detrimental to sound governance until well after the second world war. This article therefore tries to understand how this early bill of rights was regarded at the time. Who suggested, or demanded, its inclusion? How did they expect it to be applied? And how did the debate reflect and influence thinking about constitutional law in Britain and the empire?  相似文献   
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Daniel B. Klein 《Society》2018,55(6):477-481
Jordan Peterson says that postmodernists say no interpretation is better than another. I would no sooner identify Peterson’s adversaries as those who have been misled by “postmodernism” than I would identify them as misled by “sustainability,” “diversity,” “multiculturalism,” or “intersectionality.” Such fare is mainly symptomatic. “Postmodern” invocations are often like “sustainability” invocations: inessential. This piece is not a defense of postmodernism. It is a critique of PoMo-bashing.  相似文献   
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The activism of women Conservatives helped Tory democracy to adapt and survive in inter-war Lancashire at a time when it was under strain due to the arrival of Labour as a significant electoral force. This article utilises the surviving records of the party in Lancashire to examine the various ways that women entered, navigated, justified and expanded their membership and function in inter-war Conservatism. It acknowledges the limits on women's advancement and influence, but it also highlights how some women made significant progress in rising through the party structures, and how women's branches facilitated this political mobility. It challenges the assumption that women Conservatives were preoccupied with sociability and discussing domestic issues, and reveals their contribution to the electoral success of the party at local level, and interaction with Lancashire's distinct tradition of Conservatism.  相似文献   
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In this article, we present findings from a grant-funded initiative to replace traditional, proprietary textbooks with an open content textbook under a Creative Commons license in the introductory American government course (POLS 1101) at Middle Georgia State University. We find that the use of an open content textbook led to somewhat negative effects on student learning outcomes and student course satisfaction, although the associated lower textbook cost increased textbook accessibility to students. We conclude with some suggestions to those adopting textbooks in this course and to the wider discipline regarding measures that may lead to more unequivocally positive outcomes than those experienced in this study.  相似文献   
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