Unusual suicides with chain saws

Two cases of suicide with bandsaws, undertaken by workers in carpenters' workshops are reported and discussed. Their choice of this method was based on the fact that they knew how dangerous such machines were. Both cases were watched by witnesses, who could not intervene due to the speed of the events. It was possible to exclude accident or homicide.     

Studies on asphyxia: lipids in the alveoli of rats in hypoxic state

Biochemical characterization in alveolar lavage fluids of rats which had inhaled 5% oxygen, carbon dioxide and carbon monoxide was studied in comparison with control rats. The protein content, consisting mainly of serum albumin, markedly increased in the hypoxic states. The phospholipid content also increased one and a half to two times as much as in the control rats. The phospholipids which increased in the alveoli were mainly pulmonary surfactant phospholipids, i.e. phosphatidylcholine and phosphatidylglycerol. The phospholipid profiles did not appear to be affected by the leakage of plasma lipids. These findings indicate that pulmonary surfactant phospholipids accumulate in the alveoli of rats in the hypoxic states examined here.     

Suicide with an unusual shotgun

The authors describe a special case of suicide, committed by a self-constructed nailgun. The inshot-wound, localized in the mouth, primarily remained undiagnosed. The patient survived two weeks and died of pulmonary embolism.     

Acetaldehyde accumulation during headspace gas-chromatographic determination of ethanol

The acetaldehyde accumulation in blood during the equilibration time of samples processed by gas-liquid chromatographic headspace technique is reported. The quantitative loss of blood ethanol concentration is recorded at various temperatures and times of the preheating process.When the equilibration process is performed at 40 °C, minimal errors, due to ethanol oxidation, are observed.     

The biology-policy interface: Theories of pathogenesis,benefit valuation and public policy formation

This paper reviews some of the basic concepts of cost and risk-benefit analysis in the context of toxic chemical regulation and discusses several critical complexities inherent in the practical application of this methodology. The broad qualitative use of risk-benefit analysis can be an important aid to the decision-making process. It is concluded, however, that the full-scale incorporation of a rigorous form of risk-benefit analysis into the regulatory process is inappropriate at this time and could have significant and unintended consequences.The authors wish to express their gratitude to their colleagues, Professors Norm Carruthers, Denton Marks and Dean Uyeno, and an anonymous referee for their instructive comments on an earlier draft of this paper.