Whose House is this Anyway? IDP and Refugee Return in Post-Saddam Iraq

Although many people displaced by Saddam's regime over the yearslooked forward to returning as soon as the 2003 war ended, anumber of problems emerged which continued to bedevil the returnprocess as late as one year after the war. These problems includedan unclear political future for the country, competing politicaland sectarian forces that often view IDPs and refugees as strategictools or weapons, a hesitant and initially undecided Coalitionpolicy on the return issue, unclear mandates for the variousactors that could assist with returns, lack of funding, andmost importantly of all, an extremely poor security situationwhich has impeded or even blocked all progress on the returnissue. Nonetheless, because Iraq's Ba'athist dictatorship wasthe overwhelming cause of displacement in the country to beginwith, the future does hold some hope for Iraqi displaced persons.This paper examines the causes of return problems in Iraq andhow various authorities in post-Ba'athist Iraq are addressingthe return issue. Particularly around the contested city ofKirkuk, problems relating to the return issue risk ignitingethnic conflict and possibly even civil war in Iraq as a whole.The article examines the return issue for the period from March2003 to June 2004, focusing especially on northern Iraq andKirkuk. The research presented here is based on fieldwork conductedin Iraq by the author between September 2003 and May 2004. Theauthor went to Iraq independently, with the assistance of aCanadian Department of National Defence post-doctoral researchgrant. Interviews were conducted with US and Coalition ProvisionalAuthority officials, Iraqi Interim Government officials, KurdistanRegional Government officials, NGO workers, and IDPs themselvesduring visits to camps around Kirkuk and Baghdad.     

DNA typing: an accessory evidence in doping control

A clear positive case for anabolic steroids doping was confounded by alleged urine tampering during doping control procedures. Review of the chain of custody showed no flaws, but nevertheless the athlete was adamant that the urine sample should be analyzed for DNA in order to support her contention that she was not the donor of the sample. The results obtained showed that the urine sample that scored positive for steroids contained nuclear DNA that could not be matched to the DNA obtained from the athlete's blood. On the other hand, the same urine sample contained mitochondrial DNA whose nucleotide sequences spanning the hyper variable regions HV1 and HV2 proved to be identical to those determined in mitochondrial DNA amplified from the athlete's blood. The occurrence of an extraneous genotype is compatible with exogenous nuclear DNA admixture to the athlete's urine. Alternatively, taking in consideration the mitochondrial DNA, we could not exclude that a sibling or a maternal relative of the athlete could have acted as a donor of the urine utilized for doping control and DNA analysis. Both situations point to possible tampering of the urine by the athlete. Adjudication at CAS maintained previous national and international federation decision that there was no proof of a chain of custody flaw to justify the athlete's allegation of urine substitution after collection.     

Empirical analysis of the STR profiles resulting from conceptual mixtures

Samples containing DNA from two or more individuals can be difficult to interpret. Even ascertaining the number of contributors can be challenging and associated uncertainties can have dramatic effects on the interpretation of testing results. Using an FBI genotypes dataset, containing complete genotype information from the 13 Combined DNA Index System (CODIS) loci for 959 individuals, all possible mixtures of three individuals were exhaustively and empirically computed. Allele sharing between pairs of individuals in the original dataset, a randomized dataset and datasets of generated cousins and siblings was evaluated as were the number of loci that were necessary to reliably deduce the number of contributors present in simulated mixtures of four or less contributors. The relatively small number of alleles detectable at most CODIS loci and the fact that some alleles are likely to be shared between individuals within a population can make the maximum number of different alleles observed at any tested loci an unreliable indicator of the maximum number of contributors to a mixed DNA sample. This analysis does not use other data available from the electropherograms (such as peak height or peak area) to estimate the number of contributors to each mixture. As a result, the study represents a worst case analysis of mixture characterization. Within this dataset, approximately 3% of three-person mixtures would be mischaracterized as two-person mixtures and more than 70% of four-person mixtures would be mischaracterized as two- or three-person mixtures using only the maximum number of alleles observed at any tested locus.     

The Microbial Rosetta Stone database: A common structure for microbial biosecurity threat agents

Infectious microorganisms are important to multiple communities engaged in biodefense and biosecurity, including the agencies responsible for health, defense, law enforcement, agriculture, and drug and food safety. Many agencies have created lists of high priority infectious microorganisms to prioritize research efforts or to formally control the possession and distribution of specific organisms or toxins. However, the biological classification of infectious microorganisms is often complex and ambiguous, leading to uncertainty and confusion for scientists involved in biosecurity work. To address this problem, we created a database, known as the Microbial Rosetta Stone, which resolves many of these ambiguities and includes links to additional information on the microbes, such as gene sequence data and scientific literature. Here we discuss the efforts to coordinate organism names from pathogen lists from various governmental agencies according to biological relatedness and show the overlap of high-priority organisms from multiple agencies. To our knowledge, this is the first comprehensive coordination of pathogens, synonyms, and correct taxonomic names. The organized tables and visual aids are freely available at http://www.microbialrosettastone.com. This website provides a single location where access to information on a broad range of disease-causing organisms and toxins is available to members of the biosecurity community.