Acidic and neutral drugs screen in blood with quantitation using microbore high-performance liquid chromatography–diode array detection and capillary gas chromatography–flame ionization detection

Blood previously acidified with aqueous saturated ammonium chloride solution was extracted with ethyl acetate. The dried extract was subjected to acetonitrile–hexane partition. The acetonitrile portion was analysed for the presence of acidic and neutral drugs by HPLC–DAD (200 mm×2.1 mm I.D. microbore ODS-Hypersil column) and GC–FID (25 m narrow-bore×0.25 mm I.D. HP-5 column with 0.33 μm film thickness). The protocol was found to be suitable for both clinical toxicology (including emergency toxicology) and postmortem toxicology. At least 66 drugs of interest were unequivocally identified by RRTs (HPLC) and UV spectra (DAD) match while another 12 were unequivocally identified by double RRTs match (HPLC and GC). Quantitation was facilitated by incorporating calibration blood standards in each assay batch. The five drugs most commonly encountered in clinical blood specimens (1150 cases) were: paracetamol (47.4% of the cases); chlormezanone (6.6%), theophylline (1.74%), naproxen (1.65%) and mefenamic acid (1.56%). The following drugs were detected in toxicologically significant quantities in postmortem blood specimens (245 cases): phenobarbitone (1.22% of the cases), naproxen (0.82%), chlormezanone (0.82%), theophylline (0.82%), carbamazepine (0.41%) and paracetamol (0.41%).     

消费主义会过早耗损中国的发展资本吗?

在中国人均GDP刚过1000美元,贫富差距扩大的情况下,中国正在提前迈入奢侈品消费的大国.虽然消费结构向发展型、享受型升级,消费水平的提高是文明进步的表现,然而,消费主义的盛行会在国家还未壮大时就过早消耗掉继续发展的资本.所以,必须对流行于中国的消费主义保持应有的警惕,并从国家层面节制过度消费.     

The Determinants of Palestinians' Attitudes Toward Peace with Israel

This study explains the variations in the Palestinians' support of the peace process with Israel. It uses multivariate Logit analysis, employing a large public opinion poll conducted in January 2000. It tests seven hypotheses, drawn from various perspectives, on the conditions of Palestinian support of or opposition to the peace process.
The study supports several of our hypotheses including the positive association between the Palestinians' perceptions of democracy and the support of peace and Palestinian women's support of the peace process. These results are important because they reconfirm the findings of the vast international relations literature, which established a strong linkage between democracy and peace and that women are more peace-oriented than men.
The study further suggests that the Palestinians associate their support of the peace process positively with their trust of domestic political institutions, a sound nation-building process, and governmental public accountability, and negatively with the perception of governmental corruption. It also reveals that the Palestinians' positive evaluation of their domestic institutions and Israel's commitment to a just and fair settlement to the conflict are more important determinants of the support of the peace process than efforts to improve their economic conditions and that the economic conditions have, at best, a small impact upon the support of or the opposition to peace. Lastly, the study points to the presence of a positive relationship between support of the peace process and each of political institutionalization, party identification, and the second level of leaders. This finding points to an emerging trend among Palestinians toward political maturation and stabilization of their domestic politics.     

A case of sudden infant death due to massive hemorrhage in primitive neuroectodermal tumor.

A case of the sudden death of a 14-month-old girl due to massive hemorrhage in a primitive neuroectodermal tumor (PNET) is presented along with a review of the relevant literature. PNET is a rare, malignant brain neoplasm occurring predominantly in children.     

G3M T typing by dot immunobinding with monoclonal anti-G3M T antibody

Dilutions of 100 serum samples of various GM phenotypes were dotted onto a nitrocellulose membrane. The serum dot-blots were detected with peroxidase-labeled anti-G3M T monoclonal antibody (anti-G3M T MAb). Up to a 1 : 256 dilution could be G3M T-typed correctly. By use of anti-G3M T MAb and peroxidase-labeled anti-mouse IgG or the biotin-avidin system instead of use of labeled anti-G3M T MAb, up to a 1 : 512 or 1 : 1024, respectively, dilution was typable. As with previous work with G3M G MAb, the dot immunobinding (DIB) method for G3M T typing was found very simple and practical.     

"天北新区"--城市发展模式的创新

"天北新区"是城市发展模式的一种创新,既是奎屯市的派出机构又是农七师的派出机构,实行既双重管理又独立运作的管理体制,享有除工商、税务之外的全部的政府管理职权.这一城市发展模式对新疆21世纪城市化建设提供了重要的经验,为新疆城市化建设探索了一种新的发展模式.     

Democratization in East Asia in the late 1980s: Taiwan breakthrough,Hong Kong frustration

Political history took an unexpected turn in East Asia in the late 1980s. The booming movement in Hong Kong had gone downhill and suffered defeat, while the authoritarian Taiwan state actively sponsored genuine democratic reforms. What then explains the Taiwan democratic breakthrough and the Hong Kong democratic frustration? This article argues that conventional explanations offered in the modernization, the dependency, and the class literature—such as culture, liberal colonialism, wealth, new middle class, bureaucratic-authoritarian state, crises, and absence of conservative class coalition—are unable to account for the divergent paths of democratic development in Taiwan and Hong Kong. As an alternative, this article presents a model that highlights the importance of conjuncture factors. It is argued that since Taiwan and Hong Kong have shared similar structural conditions, researchers have to bring in conjuncture factors such as the historical event of Chinese unification, the capacity of the political agency to promote democratic reforms, and the strategy of protest in order to explain the Taiwan breakthrough and the Hong Kong frustration.     

K~+/Na~+比值与损伤时间的关系

本文使用原子吸收光谱法测定12只大鼠36个烧伤局部肌肉标本的 K~+/Na~+值,检测结果:生前60、 30、 15min 以及死后20min 肌肉标本的 K~+/Na~+值比对照组分别下降:69～94％(平均86％)、56～89％(平均77％)、47～82％(平均71％)、4～38％(平均27％),此结果经统计学处理,表明生前伤与死后伤的 K~+/Na~+比值的下降率有明显差异。同时发现生前损伤的各实验组随存活时间的延长,K~+/Na 比值的下降率有增加的倾向。笔者认为,此方法是烧伤时间推断的一种简便,可靠的方法,对法医学实践有一定实用价值。     

AGE,DIFFERENTIAL EXPECTATIONS,AND CRIME DESISTANCE*

We specify an individual-level model linking crime desistance to estimates of legal risk, differential expectations, degree of past success at legitimate and criminal pursuits, and age. OLS and logistic regression procedures are used to estimate the model using longitudinal data on serious, previously imprisoned offenders. As predicted, age decreases estimates of the likely payoffs from crime and legitimate employment. Contrary to predictions, age is unrelated to the perceived legal risk of renewed criminal participation. Age, past success at avoiding confinement, expectations of success from crime, and level of education are significant predictors of crime desistance. Neither the perceived legal risk of crime nor expectations of success through straight pursuits significantly predict desistance. We suggest an interpretation for these anomalous findings.