The Implications of Brexit for the Caribbean’s Future Relationship with Britain and the EU

Abstract

The UK Brexit referendum to leave the EU has created concerns internationally, particularly for countries that have formal trade, aid and investment treaties with the EU and none with Britain alone. The notion of a Commonwealth Free Trade Agreement (FTA) is a non-starter and would bring no benefits to the Caribbean. But, Britain outside the EU deprives the Caribbean of a sympathetic voice on a range of issues, including financial services, and alters the level of official development assistance that will be available from remaining EU members that have no historical relationship with the English-speaking Caribbean. The importance of the UK as a market for their goods and services make it imperative for Caribbean countries to start early ‘talks’ with London so as not to be crowded out by FTAs that the UK will conclude with countries larger and richer than the Caribbean. At the same time, Brexit provides an opportunity for the Caribbean to revisit its unsatisfactory Economic Partnership Agreement with the EU. Caribbean countries need to determine their objectives and take early initiatives to realise them.     

Detection of Acetaminophen–Protein Adducts in Decedents with Suspected Opioid–Acetaminophen Combination Product Overdose

Acetaminophen overdose is a leading cause of drug‐induced liver failure in the United States. Acetaminophen–protein adducts have been suggested as a biomarker of hepatotoxicity. The purpose of this study was to determine whether protein‐derived acetaminophen–protein adducts are quantifiable in postmortem samples. Heart blood, femoral blood, and liver tissue were collected at autopsy from 22 decedents suspected of opioid–acetaminophen overdose. Samples were assayed for protein‐derived acetaminophen–protein adducts, acetaminophen, and selected opioids found in combination products containing acetaminophen. Protein‐derived APAP‐CYS was detected in 17 of 22 decedents and was measurable in blood that was not degraded or hemolyzed. Heart blood concentrations ranged from 11 ng/mL (0.1 μM) to 7817 ng/mL (28.9 μM). Protein‐derived acetaminophen–protein adducts were detectable in liver tissue for 20 of 22 decedents. Liver histology was also performed for all decedents, and no evidence of centrilobular hepatic necrosis was observed.     

Do Open Primaries Improve Representation? An Experimental Test of California's 2012 Top‐Two Primary

To improve representation and alleviate polarization among US lawmakers, many have promoted open primaries—allowing voters to choose candidates from any party—but the evidence that this reform works is mixed. To determine whether open primaries lead voters to choose ideologically proximate candidates, we conducted a statewide experiment just before California's 2012 primaries, the first conducted under a new top‐two format. We find that voters failed to distinguish moderate and extreme candidates. As a consequence, voters actually chose more ideologically distant candidates on the new ballot, and the reform failed to improve the fortunes of moderate congressional and state senate candidates.     

Pregnancy and Intimate Partner Violence in Canada: a Comparison of Victims Who Were and Were Not Abused During Pregnancy

The purpose of this study was to examine risk factors, indicators of severity, and differences in post-violence health effects for victims who experienced intimate partner violence (IPV) during pregnancy compared to victims who experienced IPV outside the pregnancy period. Data were from Statistics Canada’s 2009 General Social Survey. Among IPV victims, 10.5 % experienced physical and/or sexual violence during pregnancy. Victims who had experienced violence during pregnancy were more likely than victims who were not abused during pregnancy to experience both less severe and more severe forms of violence. In fully adjusted models, younger age, separated or divorced marital status, as well as partners’ patriarchal domination, destruction of property, and drinking were significant predictors of pregnancy violence. Measures indicative of more severe violence and of a number of adverse post-violence health effects were significantly elevated among victims who experienced pregnancy violence relative to victims who were not abused during pregnancy. Implications of these findings are discussed.     

Venture’s economic impact in Australia

We empirically compare the contributions of venture capital (VC) and private equity backed firms, including those backed by government subsidized innovation investment funds (IIFs), in the Australian economy by analyzing employment, R&D, patents, time to IPO, and market capitalization from market inception to August 2012. Overall, the data highlight a central role for VC and IIF investment in facilitating R&D, innovation, and economic growth. Our IIF findings highlight the success of government sponsorship of VC under the Australian program design, which is sharply in contrast with the lack of success of government venture programs in other countries.     

“I Won't Back Down?” Complexity and Courage in Government Executive Decision Making

Senior government executives make many difficult decisions, but research suggests that individual cognitive limitations and the pathologies of “groupthink” impede their ability to make value‐maximizing choices. From this literature has emerged a normative model that Irving Janis calls “vigilant problem solving,” a process intended for the most complex decisions. To explore its use by senior public officials, the authors interviewed 20 heads of subcabinet‐level organizations in the U.S. federal government, asking how they made their most difficult decisions. The initial focus was on whether they employed a vigilant approach to making decisions that were informationally, technically, or politically complex. Most executives identified their single most‐difficult decision as one that required courage; they often made such courageous decisions after personal reflection and/or consultation with a small number of trusted advisors rather in ways that could be described as vigilant. The different approaches for making complex decisions, compared with those involving courage, are discussed and a contingency model of effective executive decision making is proposed that requires leaders (and their advisors) to be “ambidextrous” in their approach.     

Modelling the dynamics of support for a right-wing populist party: the case of UKIP

Similar to a number of other right-wing populist parties in Europe, Great Britain's United Kingdom Independence Party (UKIP) has experienced increased public support in recent years. Using aggregate data from monthly national surveys conducted between April 2004 and April 2014, time series analyses demonstrate that the dynamics of UKIP support were influenced by a combination of spatial and valence issues. A spatial issue, Euroscepticism, was fundamental, with UKIP support moving in dynamic equilibrium with changing public attitudes towards EU membership. In addition, widespread anti-immigration sentiment and dissatisfaction with the performance of the Conservative–Liberal Democrat coalition government combined with the “oxygen of publicity” to propel UKIP's surge. The political context after the 2010 general election helped as well by enabling UKIP to benefit from valence considerations. Many voters continued to doubt the competence of the major opposition party, Labour, while the Liberal Democrats were part of the government and, hence, unavailable as a protest vehicle. Since many of the forces driving UKIP support are beyond its control, the party's prospects are highly uncertain.     

Retributivism and Over-Punishment

Law and Philosophy - Lately it has become a commonplace to complain about the injustice of mass incarceration. I share the sentiment that this phenomenon has been an injustice. But it also has...     

Compulsory treatment with clozapine: a retrospective long-term cohort study

BACKGROUND: Clozapine is the gold standard in treatment of treatment-resistant psychotic patients. We know little about the effects of compulsory treatment in patients unwilling to accept the necessary treatment. AIMS: To assess the effectiveness, tolerability and safety of compulsory treatment with clozapine (CTC). METHOD: A cohort of 17 consecutive patients given compulsory treatment with clozapine were rated retrospectively by their treating psychiatrists on the basis of their case notes. RESULTS: CGI-S decreased significantly over time until last observation after a mean of more than 15 months. No patient deteriorated as measured by CGI-I. At last observation as many as ten of the 11 patients still on clozapine were classified as much to very much improved. The degree of custodial restriction at last observation showed improvement in 11 patients and no change in six. No serious adverse events were observed. CONCLUSION: A trial of compulsory treatment with clozapine showed this treatment to be feasible, effective, safe and well tolerated.