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71.
72.
Tahir MA Herrera RJ Khan AA Kashyap VK Duncan G Barna C Budowle B Rowold DJ Amjad M Sinha S 《Journal of forensic sciences》2000,45(6):1320-1323
Blood samples were collected from 115 individuals residing in the Pakistani state of West Punjab and 81 Bengali individuals residing in the state of East Bengal, India. These samples were analyzed for the loci HLA-DQA1, PM (LDLR, GYPA, HBGG, D7S8, and GC) and eight short tandem repeats: CSF1PO, TPOX, THO1, vWA, D16S539, D7S820, D13S317, and D5S818. Departures from Hardy-Weinberg (HWE) were observed in Punjabi population at LDLR, THO1, D13S317, D5S818, and D16S539 and at CSF1PO and THO1 in Bengali population. 相似文献
73.
The US Court of Appeals for the Federal Circuit has confirmedthat a patent claim may be invalidated for what was previouslyconsidered to be a minor technical defect: in essence, a dependentclaim is invalid if it is not a subset of the claim from whichit purports to depend. While Ranbaxy succeeded on this point,its generic Lipitor product was still held to have infringedPfizer's enantiomer patent, which expires on 24 March 2010,with pediatric exclusivity. 相似文献
74.
A lack of narrow dependent claims, which focus on the technicaladvance of the invention, meant that the main claim was heldinvalid as being obvious. 相似文献
75.
Duncan Ivison 《Political studies》1999,47(1):83-99
According to an essentially Hobbesian account of political order, the claims of cultural and national minorities within a state to some form of constitutional or institutional recognition are morally suspect and politically undesirable. Underlying this Hobbesian logic is a particular understanding of the relation between law and politics. 'Negative constitutionalism' is focused primarily on limiting the damage government can do. However the pursuit of constitutional minimalism runs up against the challenges presented by deeply diverse political communities. By investigating the manner in which Hobbes has been invoked in arguments concerning the relation between the rule of law and the 'politics of recognition', I argue (i) that the distinction between the rule of law and politics is fundamentally unstable, and (ii) that in invoking Hobbes, modern theorists have missed an important element of Hobbes's own argument—namely, his appreciation of this instability. As an example, I examine the way Hobbes is used in some of John Gray's recent writings on pluralism and liberalism. 相似文献
76.
Duncan Morrow 《政治学》1997,17(1):39-44
The unexpectedly early Austrian elections of 1995 resulted in the first setback for Jor Haider's dynamic far-right 'Freieitlichen' movement since he became party leader in 1986. The Austrian Social Democrats managed to overcome early inertia and mobilise the collective fear of many Austrians about the political and economic future and increase their parliamentary strength. Nevertheless, after the elections they used their strengthened position to introduce a programme of sharp cuts in the traditionally generous welfare budget which had been previously demanded by their opponents. 相似文献
77.
This paper provides an empirical appraisal of the influence ofpolitics on the evolution of unemployment rates in 13industrialized democracies (12 European Union countries andthe U.S.) from 1960 to 1999. We conduct new tests ofopportunistic and partisan business cycle models, using richerdata and more general specifications than previous studies. Incontrast to most previous studies, we pay particular attentionto the importance of labor market structure in conditioningthe influence of politics on unemployment. We also investigatethe relationship between political stability and economicstability. The results suggest the existence of partisan effects, withhigher unemployment rates prevailing under ``right'' partiesthan ``left'' parties. There is more support for ``rational''partisan models that embody transient partisan impacts thanfor models with permanent effects. We find evidence that unionpower is associated with higher average unemployment rates,but that centralized bargaining institutions tend to lowerunemployment rates. The evidence also suggests that morefragmented coalition governments are associated with higherunemployment rates than single party governments. 相似文献
78.
79.
This article examines an area of cost-benefit methodology which has come under increasing philosophical scrutiny in recent years: the appropriate treatment of individuals' preferences. We illustrate some of the difficulties involved in assessing preferences in the context of a concrete example: the evaluation of a rural water supply project in southern Haiti. Four problems in the application of cost-benefit principles are discussed: (1) how to count the social value of private water taps connected to homes if they are preferred for prestige reasons, (2) how to assess husbands' preferences concerning the time savings by wives who previously carried water from more distant sources, (3) how to count preferences based on a respondent's desire to support general community welfare, and (4) how to evaluate a water project when people's preferences may change after the new water system is installed. We argue that policy analysis will be improved by presenting philosophical arguments as to why some preferences should be included in the evaluation and others ignored. 相似文献
80.
THE INTERNAL AND EXTERNAL VALIDITY OF THE REGRESSION DISCONTINUITY DESIGN: A META‐ANALYSIS OF 15 WITHIN‐STUDY COMPARISONS 下载免费PDF全文
Duncan D. Chaplin Thomas D. Cook Jelena Zurovac Jared S. Coopersmith Mariel M. Finucane Lauren N. Vollmer Rebecca E. Morris 《Journal of policy analysis and management》2018,37(2):403-429
Theory predicts that regression discontinuity (RD) provides valid causal inference at the cutoff score that determines treatment assignment. One purpose of this paper is to test RD's internal validity across 15 studies. Each of them assesses the correspondence between causal estimates from an RD study and a randomized control trial (RCT) when the estimates are made at the same cutoff point where they should not differ asymptotically. However, statistical error, imperfect design implementation, and a plethora of different possible analysis options, mean that they might nonetheless differ. We test whether they do, assuming that the bias potential is greater with RDs than RCTs. A second purpose of this paper is to investigate the external validity of RD by exploring how the size of the bias estimates varies across the 15 studies, for they differ in their settings, interventions, analyses, and implementation details. Both Bayesian and frequentist meta‐analysis methods show that the RD bias is below 0.01 standard deviations on average, indicating RD's high internal validity. When the study‐specific estimates are shrunken to capitalize on the information the other studies provide, all the RD causal estimates fall within 0.07 standard deviations of their RCT counterparts, now indicating high external validity. With unshrunken estimates, the mean RD bias is still essentially zero, but the distribution of RD bias estimates is less tight, especially with smaller samples and when parametric RD analyses are used. 相似文献