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151.
Piket ER 《American journal of law & medicine》2012,38(1):7-62
National advisory committees have considered the obligations owed to research participants in the event of research-related injuries. These committees have repeatedly concluded that injured research participants are entitled to compensation for their injuries, that the tort system provides inadequate remedies, and that the United States should adopt no-fault compensation. But because the advisory committees have made no concrete proposals and have taken no steps toward implementing no-fault compensation, the United States continues to rely on the tort system to compensate injured research participants. This Article argues that recent legal developments and a transformation in the global research landscape make maintaining the status quo morally indefensible and practically unsustainable. Recent legal developments exacerbate the longstanding difficulties associated with the tort system as a method of compensation; nearly every injured research participant will have difficulty recovering damages, and certain classes of injured research participants--those in federal research and those abroad--are prevented from recovering altogether, resulting in substantial unfairness. In the past ten years, many of the countries substantially involved in research have mandated systematic compensation. By not mandating compensation, the United States has become a moral outlier and risks having its noncompliant research embargoed by foreign ethics committees, thereby delaying important biomedical advances. This Article examines alternative compensation mechanisms and offers a concrete no-fault compensation proposal built on systems already in place. The proposed system can be implemented in the United States and countries around the world to help harmonize various national compensation systems and to more equitably and effectively make those injured by research whole. 相似文献
152.
Gilchrist E Jongekrijg F Harvey L Smith N Barron L 《Forensic science international》2012,219(1-3):50-56
Gunshot residue (GSR) is commonly analysed in forensic casework using either scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX) or gas chromatography-mass spectrometry (GC-MS). Relatively little work has been reported on the post-discharge GSR content of non-metallic inorganic or low molecular weight organic anions to distinguish between different ammunition types. The development of an analytical method using suppressed micro-bore anion exchange chromatography (IC) is presented for the analysis of GSR. A hydroxide gradient was optimised for the separation of 19 forensically relevant organic and inorganic anions in <23min and sensitivities of the order of 0.12-3.52ng of anion detected for all species were achieved. Along with an optimised extraction procedure, this method was applied to the analysis of post-ignition residues from three selected ammunition types. By profiling and comparing the anionic content in each ammunition residue, the possibility to distinguish between each type using their anionic profiles and absolute weight is presented. The potential for interference is also discussed with respect to sample types which are typically problematic in the analysis of GSR using SEM-EDX and GC-MS. To the best of our knowledge this represents the first study on the analysis of inorganic anions in GSR using suppressed ion chromatography. 相似文献
153.
154.
ABSTRACT The increase in life expectancy for adults with learning disabilities has extended the caring role for their parents. This study examined the experiences of older parents who provide long-term care for their adult children with learning disabilities and how they conceptualise their quality of life. Data were collected using semi-structured interviews with 27 older parent carers from four London boroughs and were analysed using framework technique. Findings indicate that most parents appraised their quality of life positively and reported benefits, despite the challenges they had to negotiate daily. The benefits from caregiving, more so in later life, were: a connected family from shared caregiving; a sense of belonging; purposeful living; a reciprocal relationship with their adult children; and personal transformations from providing care that improved their quality of life. The challenges that participants regularly encountered were: multiple losses (sleep, career, identity and friends); the added stress of the government’s Personalisation Agenda of caring services; struggles for access to services; searching for a diagnosis; worry about future care and fear of abuse when carers are unable to continue in their role; unhelpful attitudes of health and social care professionals; and a lack of empathy from friends as well as the public towards people with learning disabilities. Caregiving and quality of life are inextricably linked and the difficulties that parents experienced were mainly associated with socio-structural barriers, rather than their children’s disabilities. Importantly, the findings inform the practice of social workers and others who support this unique group of carers by providing new insights into how caring impacts on quality of life over time and how best these parents’ needs can be met. This study makes a specific contribution to understanding the lived realities of older carers and extends current conceptualisations of caregiving and quality of life among older people. 相似文献
155.
Criminological studies have found that men’s and women’s pathways to imprisonment differ, with risk factors such as substance abuse, mental illness, socioeconomic circumstances and past victimisation more strongly associated with female prisoners. However, limited quantitative or longitudinal research exists on how the risk factors associated with female offending may have shifted over time. This article investigates the criminal careers and pathways to imprisonment of 6,042 women incarcerated in Victoria between 1860 and 1920, and the risk factors associated with subsequent recidivism. The findings suggest that, while many of today’s risk factors were present historically, there have been notable shifts across time. 相似文献
156.
Elizabeth F. Drexler 《亚洲研究》2018,50(3):395-421
Analyzing photos and narratives of the “widows’ battalion” in Aceh, Indonesia that appeared in international and local print media between 2000 and 2002, this article traces how images of female combatants initially provided evidence of a uniformed, armed ethno-nationalist movement motivated by past state violence and linked to historical legends of women involved in armed resistance to colonialism. Subsequently, the heroines were recast as immoral young women pursuing inappropriate sexual relationships with the occupying military. The problems of intelligence gathering, double agents, and the indeterminate zone of overlap in which male soldiers collaborated in the past were rewritten as a problem of sexual or intimate relations that violated religious and cultural norms. In Aceh, the affective power and complexity of women’s positioning as both victim and combatant is fueled by the invocation of the iconic heroines of the anticolonial resistance and ideas about international human rights. Images and narration of the widows’ battalion appear to champion female combatants past and present, but in fact, contribute to the consolidation of the power of male commanders and combatants in the resistance movement. Analyses of human rights photography must consider the affective power of images beyond engaging the empathy of distant spectators to consider their role in conflict dynamics. 相似文献
157.
Organic impurity profiling of fentanyl samples associated with recent clandestine laboratory methods
Steven G. Toske PhD Jennifer R. Mitchell MS James M. Myslinski PhD Andrew J. Walz PhD David B. Guthrie PhD Elizabeth M. Guest PhD Charlotte A. Corbett PhD Emily D. Lockhart MS 《Journal of forensic sciences》2023,68(5):1470-1483
Nearly a decade ago, fentanyl reappeared in the United States illicit drug market. In the years since, overdose deaths have continued to rise as well as the amount of fentanyl seized by law enforcement agencies. Research surrounding fentanyl production has been beneficial to regulatory actions and understanding illicit fentanyl production. In 2017, the Drug Enforcement Administration (DEA) began collecting seized fentanyl samples from throughout the United States to track purity, adulteration trends, and synthetic impurity profiles for intelligence purposes. The appearance of a specific organic impurity, phenethyl-4-anilino-N-phenethylpiperidine (phenethyl-4-ANPP) indicates a shift in fentanyl production from the traditional Siegfried and Janssen routes to the Gupta-patent route. Through a collaboration between the DEA and the US Army's Combat Capabilities Development Command Chemical Biological Center (DEVCOM CBC), the synthesis of fentanyl was investigated via six synthetic routes, and the impurity profiles were compared to those of seized samples. The synthetic impurity phenethyl-4-ANPP was reliably observed in the Gupta-patent route published in 2013, and its structure was confirmed through isolation and structure elucidation. Organic impurity profiling results for illicit fentanyl samples seized in late 2021 have indicated yet another change in processing with the appearance of the impurity ethyl-4-anilino-N-phenethylpiperidine (ethyl-4-ANPP). Through altering reagents traditionally used in the Gupta-patent route, the formation of this impurity was determined to occur through a modification of the route as originally described in the Gupta patent. 相似文献
158.
Norm Diffusion and Reputation: The Rise of the Extractive Industries Transparency Initiative 下载免费PDF全文
Transparency in the extractives sector is widely seen as an important tool for improving accountability and deterring corruption. Yet for those very reasons, it is a puzzle that so many governments in corruption‐prone countries have voluntarily signed up to greater scrutiny in this area by joining the Extractive Industries Transparency Initiative (EITI). We argue that EITI serves as a reputational intermediary, whereby reformers can signal good intentions and international actors can reward achievement. International and domestic actors thus utilize EITI to diffuse the norm of resource transparency and to advance reformist aims in a highly problematic policy area. 相似文献
159.
Jane Elizabeth Lavery 《Journal of Iberian and Latin American Studies》2016,22(3):197-213
As a writer whose fiction is known for its transgressive themes and forms, it is no surprise that the Mexican author Ana Clavel has continued to revel in such contraventions in her novella Las ninfas a veces sonríen (2012). In this article I seek to examine how these, also new transgressions, materialize in the novella specifically within a queer framework. The queer showcases Las ninfas’ exploration of “outlaw” sexual desires as well as the fantastical and intertextual genre-bending. By defying heteronormative sexual normalcy, Clavel is seen to challenge certain “givens” within (Mexican) society, whether these be religious, moral, sexual, or cultural, and thus creating a fascinating representation of society’s particular fears, anxieties, and disavowed desires. In the context of the female character’s sexual experiences, transgressive queereness can be understood by making reference to various theories including those of Kristeva’s abjection/uncanny and Creed’s/Braidotti’s monstrous feminine, whereby the female is positioned in terms of an ambiguous oscillation between unthreatening object of male desire, monstrosity, and celebratory female sexual agency. Ultimately by thus delving into outlawed “no-deseos”, Las ninfas can be posited as a prime example of a Barthesian text of “jouissance” which disrupts the reader’s pleasurable reading experience. 相似文献
160.
This paper explores Senate policy-making toward Israel from 1993–2002. Previous scholarship suggests that congressional policymaking toward Israel is heavily influenced by the ethnic and religious identification of both legislators and their constituents, not simply by legislators' abstract perceptions of the national interest. Other literature de-emphasizes the likelihood that constituent interests will affect Congressional foreign policy making. We test for an impact of both elite and constituent characteristics on Congressional support for Israel, using sponsorship–cosponsorship decisions in the 103rd–107th Congresses. Israel's strongest supporters in this period are shown to be Jewish, conservative, Republican, and evangelical senators. Notably, elite characteristics (partisanship, ideology, and religion) matter more than constituency factors, with the exception of the Jewish population in senators' home states. While Jewish and conservative senators have long been vocal supporters of Israel, evangelical and Republican senators have not historically taken such a strong pro-Israel stance; hence they are relatively new additions to the active pro-Israel coalition. Thus the pro-Israel coalition shows both continuity and change as it has broadened to include new partners. However, we suggest that this coalition is not necessarily stable and may undergo further evolution in the future. 相似文献