N. A. Graebner,R. D. Burns,and J. M. Siracusa,Reagan, Bush,Gorbachev: Revisiting the End of the Cold War

Faced with creating a grand strategy for American foreign policy in the post–Cold War world, the Clinton Administration launched the strategy of ‘Democratic Enlargement.’ This analysis makes two contributions to the existing literature on the topic. First, it investigates the role of Wilsonianism and the ‘Democratic Peace Thesis’ in the discourse of the strategy of ‘Democratic Enlargement’ based on public speeches with a focus on the relationship between democracy and security. Second, it utilises securitisation theory to analyse how Clinton’s Administration used the linkage of democracy and security to legitimise humanitarian interventions in Haiti and Kosovo. By addressing ‘Democratic Enlargement’ in security terms, the Administration securitised democracy promotion and, thereby, created a discourse that helped legitimise a gradual move towards a more militaristic foreign policy during Clinton’s presidency. This discourse offered arguments later utilised by the George W. Bush Administration.     

铅镉联合染毒对大鼠大脑皮质神经细胞的氧化损伤及NAC的保护效应

为研究铅、镉联合对新生大鼠大脑皮质神经细胞的脂质过氧化损伤及N-乙酰半胱氨酸(N-ace-tylcysteine,NAC)的保护效应,以体外培养的新生大鼠原代大脑皮质神经细胞为试验对象,分17个组进行了不同铅、镉浓度的染毒和保护试验,染毒时间为12 h.经超声波粉碎细胞后,测定神经细胞超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-Px)、乙酰胆碱酯酶(TChE)活性和丙二醛(MDA)含量.结果表明,与对照组比较,铅、镉单独染毒组GSH-Px、SOD和TChE活性随染毒越量的增加呈逐渐下降趋势(P<0.05),而CAT活性及MDA含量则呈升高趋势(P<0.05),两者之间具有明显的剂量一效应关系;铅、镉联合染毒对神经细胞GSH-Px、SOD、TChE、CAT活性和MDA含量的改变均较相应的铅、镉单独染毒更为明显,部分组间有显著差异(P<0.05);NAC保护组的MDA含量显著低于相应的染毒组(P<0.05),SOD、GSH-Px、TChE和CAT活性不同程度地高于相应的染毒组,但部分组间差异不显著(P>0.05).铅、镉联合对新生大鼠大脑皮质神经细胞的氧化损伤表现协同毒性效应,NAC可以提高神经细胞的抗氧化能力,对铅、镉及其联合暴露所致的脂质过氧化损伤有一定的保护作用,但保护作用不明显.     

精神分析与公共行政:从弗洛伊德到戴蒙德

在传统公共行政学的组织理论中,一个基本的理论前提就是假设人类的行为是理性的,因而对组织的研究总是局限于研究基于人类理性所产生的规范和制度.而自从弗洛伊德创立精神分析方法以来,很多的学者开始运用这一方法来解释组织的行为,创立了精神分析的组织理论.其中,戴蒙德就是著名的代表.精神分析方法在组织理论研究中的运用,拓宽了公共行政研究的视野和思路.但同时也把组织理论从传统发展到了另一个极端,那就是过于强调人类行为的非理性,使得对组织的研究易于陷入不可知的状态。可见,精神分析方法对于公共行政学是有意义的。     

Chemical signature of ecstasy volatiles by comprehensive two-dimensional gas chromatography

A method for ecstasy volatiles 'signature' analysis based on two-dimensional gas chromatography separation and time-of-flight mass spectrometry detection (GC×GC-TOFMS) is presented. Organic impurity volatiles were extracted by head space solid phase microextraction (HS-SPME). The final column phase choice of the four different column combinations tested was a low-polarity 5% phenyl polysilphenylene-siloxane coupled with a polyethylene glycol phase, which best displayed the complex impurity profile. Second dimension ((2)D) retention time reproducibility was found to be about 1% RSD, and area reproducibility of SPME sampling was just over 5% RSD for compounds with S/N ratio of about 100. High similarity of TOFMS spectra of impurities was obtained against commercial MS libraries. 16 components from the two-dimensional profiles were selected for comparison of the 24 ecstasy tablets, most of which proved to be benzodioxole derived compounds. All tablets were correctly classified in eight groups according to their post-tabletting characteristics, when appropriate data pre-treatment was applied. Principal component analysis revealed clustering of samples according to the country of origin. Samples from Macedonia were elevated in N-formyl-MDMA and N-acetyl-MDMA while samples from Australia were elevated in 3,4-methylenedioxypropane and 3,4-methylenedioxyacetophenone. Furthermore, three components were found to be unique for one of the source countries. The additional separation of components on the (2)D column, increased response due to modulation, high acquisition rate with full mass spectra using TOFMS detection, and MS deconvolution extend the possibility of detecting additional markers and route-specific components, especially of low abundant, polar components.     

A Sequence Analysis of Nonverbal Behaviour and Deception

The ability to correctly interpret nonverbal communication (NVC) is an important ability in everyday interactions, which may use NVC techniques to identify the concealment of information. In the present study, a novel approach was used to understand NVC. Behaviour sequence analysis identified specific sequences of behaviours that indicate psychological distress caused by deception. The study involved the analysis of 55 videos of real criminals and high-power individuals that were filmed fabricating statements, which were later exposed as being untruthful at the time of being filmed. In addition, 53 clips of criminals making truthful statements were also analysed as a contrast group. Results indicated clear differences between honest and deceptive responses, such as furrowing of eyebrows in the deceptive sequences occurring more often than honest statements. In addition, sequences of behaviours were shown in the present data set, which could indicate a new method for analysing NVC and detecting psychological distress caused by deception. The possible implications and applications for police and forensic investigation are also outlined.     

Do we need warm leaders? Exploratory study of the role of voter evaluations of leaders’ traits on turnout in seven European countries

Previous research on leader effects has focused exclusively on the impact of voters’ evaluations of leaders on vote choice, disregarding possible effects on the prior step of deciding whether or not to turn out to vote. In line with the personalisation of politics thesis, leaders have a higher impact among dealigned voters. Previous studies have demonstrated that leader effects are stronger among voters who voice their dealignment – namely party switchers. However, the potential impact of leaders among those who exited (i.e., who have abstained) is still unstudied. Could leaders have a mobilisation effect and therefore trigger turnout decisions? What characteristics of party leaders are more relevant in this regard? This article is the first comparative study to examine how the evaluation of party leaders’ traits influences voter turnout in general elections. The work incorporates data from election studies across seven countries with different social contexts (Portugal, Spain, Ireland, Germany, United Kingdom, Italy and Hungary). Characteristics of leaders were grouped into two dimensions – competence and warmth – in accordance with the stereotype content model and relevant studies on leaders’ traits evaluation. Multiple binary logistic regression models were performed to analyse the predictive power of competence and warmth on turnout, controlling for sociodemographic, political ideology variables and voters’ past political behaviour. Results reinforce the personalisation of politics theory, showing the utmost relevance of warmth personality traits of leaders in voter turnout decisions. Competence personality traits were found to be relevant only in some situations. Interaction effects were also demonstrated between warmth evaluations and identifying with a right-wing party as well as past political behaviour with both warmth and competence.     

A novel platform for the modular integration of forensic assay setup and medium- to high-throughput purification of nucleic acids

With its extraction and assay setup modules, the QIAsymphony^® provides a highly flexible solution for processing forensic samples in a medium- to high-throughput scale. We tested the sensitivity of extraction, precision of sample processing, and accuracy of automated assay setup of this integrated system. Results attest to QIAsymphony's ability to isolate DNA from a spectrum of common forensic samples and process these samples without cross-contamination. Furthermore, accurate assay setup for downstream applications, like PCR, make this system highly suited for enhancing laboratory workflow.     

Model United Nations and Deep Learning: Theoretical and Professional Learning

This article demonstrates that the purposeful subject design, incorporating a Model United Nations (MUN), facilitated deep learning and professional skills attainment in the field of International Relations. Deep learning was promoted in subject design by linking learning objectives to Anderson and Krathwohl’s (2001 Anderson, Lorin W., and David R. Krathwohl (eds.). 2001. A Taxonomy for Learning, Teaching, and Assessing: A Revision of Bloom’s Taxonomy of Educational Objectives. New York: Longman. [Google Scholar]) four levels of knowledge or cognition: factual, conceptual, procedural, and metacognitive. Students demonstrated improvement in all four areas; however, this article focuses on outcomes in the conceptual and metacognitive realms as these were where students showed the most growth. In the conceptual realm, the subject aimed to increase students’ capacity to apply international relations theories. Students tended to utilize the traditional theories of realism and liberalism; however, their explanations and applications of these theories showed deep learning. In the metacognitive realm, students were able to analyze their own negotiation styles and to explain how it influenced their approach to the Model UN, thus demonstrating strong professional skills development and metacognitive growth. Learning was enhanced by the use of open access online subject materials and online communications. The subject was designed and run in a context where simulations in teaching politics and international relations are not common.