Fatal cocaine interactions: a review of cocaine-related deaths in Bexar County, Texas

Although cocaine is a widely abused illicit substance that is known to cause death, deaths due to its use appear to occur in a minority of those who use it. This report was designed to review drug-related deaths due to cocaine, and the concomitant use of other drugs/medications. A retrospective review of drug deaths at the Bexar County Medical Examiner's Office in San Antonio, Texas, was undertaken for cases where cocaine was one of the drugs implicated in causing death. Analysis was performed comparing the concentrations of cocaine and benzoylecgonine present and the absence or presence of other drugs. The data obtained showed that cocaine was toxic over a large range with deaths occurring at concentrations ranging from 0.01 to 78 mg/L. Analyses also indicated an increased lethality when cocaine is used in combination with ethanol, heroin, opiates, and antidepressant/antipsychotic medications, which is consistent with previous reports and research. Antihistamine data showed that there may be relationship between increased toxicity and co-ingestion, although more research is necessary.     

Airway obstruction by laryngeal masses in sudden and homicidal deaths

We present two cases of autopsy detection of laryngeal masses with medico-legal implications. The first is a 56-year-old man who died suddenly of asphyxia due to upper airway obstruction caused by a large glosso-epiglottic retention cyst and glottic oedema. Hypothesis of medical liability was raised, due to delayed tracheotomy as the result of repeated failed attempts at oral intubation by various physicians. Difficult oral intubation due to the presence of a laryngeal mass in an asphyxiating subject requires rapid tracheotomy. The second case deals with a 43-year-old woman who died of asphyxia due to airway obstruction, as a result of injury of a cavernous laryngeal haemangioma after homicidal manual strangulation, with severe haemorrhagic infiltration of the surrounding soft tissues. Damage to laryngeal/hypopharyngeal masses should be considered as a possible sign of manual strangulation, as well as neck skin bruises/abrasions and laryngeal haemorrhages.     

The mediational role of values in linking personality traits to civic engagement in Italian youth

In recent decades, given new forms of political participation, the involvement of young people in the civic domain begins to be a focus of many studies. The present study examined the role of personality traits and personal values in the prediction of civic engagement (CE) in Italian youth ranging in age from 19 to 29 years old involved in an ongoing longitudinal study. The multidimensionality of a scale tapping CE has been demonstrated with the examination of confirmatory factor analysis. Structural equation modeling corroborated a mediational model in which benevolence fully mediated the relationship of the traits of agreeableness and openness with civic associationism, whereas power fully mediated the relationship of the traits of agreeableness and openness with political associationism. In this mediational model men reported higher levels of power than women, whereas women reported higher levels of agreeableness and openness traits. Since basic personal traits have been identified as the root of any behavioral tendency and values have been recognized as the more flexible and changeable variables, future interventions aimed to foster CE in youth could be designed considering the strength relationship between the examined dimensions in the present study.     

Media Exposure, Current and Future Body Ideals, and Disordered Eating Among Preadolescent Girls: A Longitudinal Panel Study

Internalization of the thin body ideal is considered by many to account for the relationship between media exposure and disordered eating among girls and young women, but almost all supporting research has employed adolescent and adult samples. Using longitudinal panel survey data collected from 257 preadolescent girls at 2 points in time 1 year apart, we tested relationships between self-reported television and magazine exposure at wave 1 and current (prepubescent) and future (postpubescent) body ideals and disordered eating at wave 2. Controlling age, race, perceived body size, and body ideals and disordered eating measured at wave 1, television viewing at wave 1 predicted increased disordered eating and a thinner postpubescent body ideal at wave 2. In contrast, none of the media variables predicted a thinner prepubescent body ideal at wave 2. These findings suggest that the thin-ideal internalization construct needs refinement to enhance its developmental sensitivity.

“大学英语”精品课程建设：以“口语”为特色

根据《大学英语课程教学要求》,本文描述了以“口语”为特色,集课堂、英语寝室、计算机网络、校园文化等“四维”为系统的大学英语精品课程建设模式,要在教学改革创新中保留并丰富“口语领先”这一多年形成的传统智慧。     

The Content Analysis of the Russian Federal and Regional Basic Legislation on the Cultural Policy

The content-analysis of the Russian federal and regional basic legislation on the cultural policy has indicated a need in a deep revision of all existing regulatory legal acts, which support the state cultural policy implementation towards building a universal terminology and vesting the functions on the cultural policy implementation in the government as opposed to the statement of the departmental specific approach to the culture.     

Testing an Age-old Adage: Can Autopsy Findings be of Assistance in Differentiating Opioid Versus Cardiac Deaths?

Given the common occurrence of both opioid and cardiovascular deaths, and the concomitant use of opioids in those with cardiac disease, the present study was undertaken to see whether the old adage of using the triad of cerebral and pulmonary edema and bladder fullness to suggest an opioid death could be used to differentiate deaths due to opioid toxicity from deaths due to cardiac disease. Brain weight, lung weight, and bladder fullness were compared among opioid-related deaths, cardiac deaths, and a control population. It was found that opioid-related deaths were more likely to have heavy lungs, a heavy brain, and a full bladder, while cardiac-related deaths had smaller volumes of urine in the bladder and heavier hearts. In conjunction with a thorough investigation, these findings may be useful to forensic pathologists when determining whether a death is opioid-related, especially in the setting of concomitant cardiac disease.