Limitations in assessment of mucosal healing in inflammatory bowel disease

An emerging parameter to define the effectiveness of new therapeutic agents in clinical trials,and by extension,for use in day-to-day clinical practice has been labeled mucosal healing.It has been hypothesized that complete healing of the intestinal mucosa in inflammatory bowel diseases should result in reduced disease complications,reduced hospitalization and reduced surgical treatment.By implication,the natural history of inflammatory bowel disease might then be altered. Measurement of mucosal healing,how...     

Genetic Polymorphisms of 15 STR Loci in Gansu Hui Population

The short tandem repeat （STR） markers are widely used in human identification and paternity testing in the field of forensic geneticsm. Recent re- searches on polymorphic STRs have led to their applications to population genetics, forensic DNA database, human individual identification, paternity testing, genetic mapping, disease linkage analysis, archaeology and potential inference of the ethnic o- rigin of an individual.     

Kuwait's economy,the economic status of the GCC in general and bilateral relations between the GCC and SADC

Focusing more on South Africa's international cultural‐political‐economic strengths and weaknesses than on current domestic affairs, as it moves away from apartheid, this article examines the new South Africa's chances for ascent (development) or descent (underdevelopment) within the world system. Politically, the State will remain weak by international standards. Economically, it is in decline, largely because it is uncompetitive internationally; and these negative trends well pre‐date the unrest and sanctions of the mid‐1980s. It is concluded that the new South Africa will be fortunate to maintain its present position in the medium‐term.     

Forensic Epidemiologic and Biomechanical Analysis of a Pelvic Cavity Blowout Injury Associated with Ejection from a Personal Watercraft (Jet‐Ski)

Jet‐propelled personal watercraft (PWC) or jet‐skis have become increasingly popular. The means of propulsion of PWC, which is a jet of water forced out of small nozzle at the rear of the craft, combined with a high risk of falling off of the seat and into close proximity with the water jet stream, raise the potential for a unique type of injury mechanism. The most serious injuries associated with PWC falls are those that occur when the perineum passes in close proximity to the jet nozzle and the high‐pressure water stream enters the vaginal or rectal orifice. We describe the forensic investigation into a case of an anovaginal “blowout” injury in a passenger who was ejected from the rear seat position of a PWC and subsequently suffered life‐threatening injuries to the pelvic organs. The investigation included a biomechanical analysis of the injury mechanism, a summary of prior published reports of internal pelvic injuries resulting from PWC falls as well as other water sports and activities, and a comparison of the severity of the injuries resulting from differing mechanisms using the New Injury Severity Score (NISS). The mean (±standard deviation [SD]) NISS values for reported PWC injuries [not including the NISS of 38 in this case study] were 11.2 (±9.5), while the mean value for reported water‐skiing falls was half that of the PWC group at 5.6 (±5.2). It was concluded that the analyzed injuries were unique to a PWC ejection versus other previously described non‐PWC‐associated water sport injuries. It is recommended that PWC manufacturers help consumers understand the potential risks to passengers with highly visible warnings and reduce injury risk with revised seat design, and/or passenger seat “deadman” switches.     

Universities and the teaching of forensic sciences to lawyers—a note *

This article presents the findings of the survey conducted among business and accountancy students of the Nanyang Business School, Singapore, on the teaching of business law. The article is organised in three main sections. Section 1 formulates the framework for the research by outlining the three basic approaches adopted across many jurisdictions for the legal education of business students—the traditionalist ("black‐letter law"), the environmentalist and mixed approaches. Section 2 briefly describes the survey questions drawn up in the light of four principal objectives that, according to legal educators, the teaching of business law should achieve. Section 3 presents and examines the findings. The article concludes that law teaching at the Nanyang Business School conforms to the traditional approach. The author accordingly makes recommendations for the transformation of current teaching and assessment medthods: an injection of a great deal of “environmental” content and context‐based education; more use of actual and current cases, practical examples and a link to the business environment.     

A Theory of Terrorist Leadership (and its Consequences for Leadership Targeting)

States often target terrorist leaders with the belief that the leader's death or capture will cause the terrorist organization to collapse. Yet the history of this strategy of “leadership targeting” provides a mixed record—for every example of effectiveness, there are similar examples of ineffectiveness. The central question of this article is: what makes a terrorist leader important? Specifically, what does a terrorist leader do that no one else can do (or do as well) for the organization? To answer this question, I develop a theory of terrorist leadership that argues that leaders might potentially perform two main functions: they can provide inspiration and/or operational direction (or not for both). I also theorize as to how and why the provision of these functions changes over time as the organization itself changes. The consequences for leadership targeting flow naturally from this theory—when leaders provide these functions to the organization, leadership targeting is most likely to be effective. Case studies of Algeria, Peru, and Japan offer insights into why some cases of leadership targeting were effective and why others were not. The conclusion extends this model with an analysis of al-Qaeda's prospects after the death of bin Laden.