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21.
Hugh James Freeman 《党史博采》2010,(1)
An emerging parameter to define the effectiveness of new therapeutic agents in clinical trials,and by extension,for use in day-to-day clinical practice has been labeled mucosal healing.It has been hypothesized that complete healing of the intestinal mucosa in inflammatory bowel diseases should result in reduced disease complications,reduced hospitalization and reduced surgical treatment.By implication,the natural history of inflammatory bowel disease might then be altered. Measurement of mucosal healing,how... 相似文献
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Michael D. Freeman Ph.D. M.P.H. Todd M. Everson Ph.D.c. M.P.H. Sean S. Kohles Ph.D. 《Journal of forensic sciences》2013,58(1):237-244
Jet‐propelled personal watercraft (PWC) or jet‐skis have become increasingly popular. The means of propulsion of PWC, which is a jet of water forced out of small nozzle at the rear of the craft, combined with a high risk of falling off of the seat and into close proximity with the water jet stream, raise the potential for a unique type of injury mechanism. The most serious injuries associated with PWC falls are those that occur when the perineum passes in close proximity to the jet nozzle and the high‐pressure water stream enters the vaginal or rectal orifice. We describe the forensic investigation into a case of an anovaginal “blowout” injury in a passenger who was ejected from the rear seat position of a PWC and subsequently suffered life‐threatening injuries to the pelvic organs. The investigation included a biomechanical analysis of the injury mechanism, a summary of prior published reports of internal pelvic injuries resulting from PWC falls as well as other water sports and activities, and a comparison of the severity of the injuries resulting from differing mechanisms using the New Injury Severity Score (NISS). The mean (±standard deviation [SD]) NISS values for reported PWC injuries [not including the NISS of 38 in this case study] were 11.2 (±9.5), while the mean value for reported water‐skiing falls was half that of the PWC group at 5.6 (±5.2). It was concluded that the analyzed injuries were unique to a PWC ejection versus other previously described non‐PWC‐associated water sport injuries. It is recommended that PWC manufacturers help consumers understand the potential risks to passengers with highly visible warnings and reduce injury risk with revised seat design, and/or passenger seat “deadman” switches. 相似文献
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John C. Freeman 《The Law teacher》2013,47(1):24-27
This article presents the findings of the survey conducted among business and accountancy students of the Nanyang Business School, Singapore, on the teaching of business law. The article is organised in three main sections. Section 1 formulates the framework for the research by outlining the three basic approaches adopted across many jurisdictions for the legal education of business students—the traditionalist ("black‐letter law"), the environmentalist and mixed approaches. Section 2 briefly describes the survey questions drawn up in the light of four principal objectives that, according to legal educators, the teaching of business law should achieve. Section 3 presents and examines the findings. The article concludes that law teaching at the Nanyang Business School conforms to the traditional approach. The author accordingly makes recommendations for the transformation of current teaching and assessment medthods: an injection of a great deal of “environmental” content and context‐based education; more use of actual and current cases, practical examples and a link to the business environment. 相似文献
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Michael Freeman 《Terrorism and Political Violence》2014,26(4):666-687
States often target terrorist leaders with the belief that the leader's death or capture will cause the terrorist organization to collapse. Yet the history of this strategy of “leadership targeting” provides a mixed record—for every example of effectiveness, there are similar examples of ineffectiveness. The central question of this article is: what makes a terrorist leader important? Specifically, what does a terrorist leader do that no one else can do (or do as well) for the organization? To answer this question, I develop a theory of terrorist leadership that argues that leaders might potentially perform two main functions: they can provide inspiration and/or operational direction (or not for both). I also theorize as to how and why the provision of these functions changes over time as the organization itself changes. The consequences for leadership targeting flow naturally from this theory—when leaders provide these functions to the organization, leadership targeting is most likely to be effective. Case studies of Algeria, Peru, and Japan offer insights into why some cases of leadership targeting were effective and why others were not. The conclusion extends this model with an analysis of al-Qaeda's prospects after the death of bin Laden. 相似文献
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J M Freeman 《Journal of health politics, policy and law》1986,11(2):285-296
Standard ethical approaches to decision-making which are based on rights, duties, obligations, beneficence, or best interests often seem inadequate or insufficient when applied to the individual infant, as in the case of Baby Jane Doe. A process approach which takes account of moral theory, but which allows tolerance, within limits, for a possible range of decisions, would appear to offer more reasonable decisions. However, any decision must be based on good facts and accurate prognosis. Pending the availability of medical records on Baby Jane Doe, judgment of the decisions made at Stony Brook must be suspended. 相似文献
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