Responding to the global tobacco industry: Canada and the Framework Convention on Tobacco Control

Abstract: In a continuing quest to build and defend world markets for tobacco products, tobacco companies have long been involved in international cooperation and information‐sharing through their own international corporate networks, as well as through national and international industry trade associations. This is evidenced in tobacco industry corporate documents now freely available on the internet. In order to institute effective tobacco control policy, policy‐makers needed to become equally astute at sharing information across national boundaries and at considering the cross‐national implications of policy and legislation. The World Health Organization has been instrumental in developing the Framework Convention on Tobacco Control (FCTC), and Canada has played an important part in this effort. The FCTC contains both demand‐reduction provisions and supply‐side provisions intended to reduce tobacco use worldwide. As a signatory to the FCTC, Canada has pledged to adhere to these provisions, thereby providing Canadian public administrators with effective tools to reduce tobacco use and its associated health burden both nationally and internationally. Sommaire: En cherchant continuellement à développer et à défendre les marchés mondiaux pour les produits du tabac, les sociétés productrices de tabac sont impliquées depuis longtemps dans la coopération internationale et le partage d'informations par le biais de leurs propres réseaux de sociétés internationales et d'associations professionnelles nationales et internationales. C'est ce qui ressort des documents des sociétés productrices de tabac auxquels on peut accéder librement sur Internet. Afin d'instituer une politique efficace de contrôle du tabagisme, les décideurs politiques ont dù devenir astucieux quant au partage d'informations et à l'étude des répercussions transnationales des politiques et des lois. L'Organisation mondiale de la santé a fortement contribuéà l'élaboration de la Convention‐cadre sur la lutte contre le tabagisme (CCLCT), et le Canada a joué un rôle important sur ce plan. La CCLCT contient à la fois des dispositions relatives à la réduction de la demande et d'autres relatives à l'offre qui visent à réduire la consommation de tabac dans le monde entier. En tant que pays signataire de la CCLCT, le Canada s'est engagéà respecter ces dispositions, fournissant ainsi aux administrateurs publics canadiens des outils efficaces pour réduire la consommation de tabac et le fardeau sur la santé qui lui est associéà l'échelle nationale et internationale.     

Determination of MDMA, MDA, MDEA and MBDB in oral fluid using high performance liquid chromatography with native fluorescence detection

This paper describes the analytical methodology for the determination of MDMA, MDA, MDEA and MBDB in oral fluid. After a liquid–liquid extraction, the analysis was carried out by high performance liquid chromatography (HPLC), with fluorescence detection. The detector wavelength was fixed at 285 nm for excitation and 320 nm for emission. The mobile phase, a mixture of phosphate buffer (pH = 5) and acetonitrile (75:25), and the column, Kromasil 100 C8 5 μm 250 mm × 4.6 mm, allowed good separation of the compounds in an isocratic mode in only 10 min. The method was validated and showed good limits of detection (2 ng/mL) and quantitation (10 ng/mL) for all the amphetamine derivatives. No interfering substances were detected. A stability study of these compounds in oral fluid stored at three different temperatures (−18, 4 and 20 °C) over 10 weeks was conducted, showing a time-dependent degradation of the four compounds.     

Significance of functional and nutritive pulmonary circulation for vital reactions in the form of embolisms

The functional and nutritive circulation in the lungs is connected by anastomoses between the pulmonary and bronchial arteries. The anastomoses have the structure of blocked arteries from which arteriovenous anastomoses proceed to the peribronchial plexus. The pulmonary artery is provided with a flow impulse by the anastomoses, and oxygen-containing blood is admixed with the venous blood, thus forming an "aortalization" in the lungs. By diverting the bloodstream, venous blood can reach the bronchial artery. The peculiarities of the lung circulation are important for vital reactions in the form of macro- and microembolisms. Macroembolisms prove the functionality of the system if branches of the pulmonary artery are closed before the arteries are blocked. A hemorrhagic infarction either arises or does not arise, and the hemorrhagic infarction cannot exceed a certain limit. A microembolism is over and above the anastomoses. If the microembolism is greater, pressure in the arteria pulmonaris can cause blood from the pulmonary artery to overflow into the bronchial artery. Because arteriovenous anastomoses arise from the blocked arteries, microemboli can now reach the systemic circulation. Thus, the system described can explain the passage of microemboli into the systemic circulation, avoiding the capillaries of the lungs; on the other hand, larger microembolisms can prove the functionality of the system.     

The state action doctrine and the Local Government Antitrust Act: the restructured public hospital model

This Article analyzes the development and complexities of the antitrust state action doctrine and the Local Government Antitrust Act as these doctrines apply to both "municipalities" and private entities. The restructuring of a public hospital is used as a model to facilitate the antitrust analysis. The restructuring model, which typically involves the leasing of a hospital facility by a public entity to a private nonprofit corporation, offers the unique opportunity to compare the different standards employed under the state action doctrine and the Local Government Antitrust Act. As a practical matter, the Article provides a framework for a public hospital to evaluate the impact of corporate restructuring on its antitrust liability exposure and to develop strategies to minimize antitrust risks.     

The development of drug trade and drug control in the Netherlands: a historical perspective

Drug trade is widely seen as a phenomenon rather new to the Netherlands. However, at the beginning of the 20th century the Dutch pharmaceutical industries were already extensively involved in the production of both opiates and cocaine, and they went on exporting large quantities of these drugs after the Opium Act (1919) took force. Until the 1960s, arrests were not at all common, and these largely affected minority groups like Chinese opium smokers and black marijuana users. Since then, drug control efforts have increased by leaps and bounds. At first, cannabis was the main target; then the focus turned to heroin, and that was later joined by cocaine. This paper traces the history of the drug trade and drug control in the Netherlands, with emphasis on their development in Amsterdam. The conclusion is reached that, in spite of drastic changes in both drug trade and drug control, certain ideologies, constructs and strategies have remained remarkably stable.