Identification of 2‐(ethylamino)‐1‐(4‐methylphenyl)‐1‐pentanone (4‐MEAP), a New “Legal High” Sold by an Internet Vendor as 4‐Methyl Pentedrone

Online vendors are offering a new legal high, 4‐methylpentedrone (4‐MPD). Information for potential users provided by internet vendors of 4‐MPD includes incorrect structures and nonexistent CAS numbers. A sample of 4‐MPD was obtained and analyzed using GC‐MS, NMR, and LC‐EIS. The fragmentation data from the GC‐MS and LC‐EIS produced an M‐1 ion that suggested the molecular mass was 219 amu, rather than 205 amu as calculated for 4‐methylpentedrone. The difference in molecular mass corresponded to the addition of a methyl group. Based on the mass and fragmentation pattern, two standards were synthesized, 2‐(ethylamino)‐1‐(4‐methylphenyl)‐1‐pentanone and 1‐(4‐methylphenyl)‐2‐(propylamino)‐1‐butanone. The synthesis involved bromination of the appropriate ketone followed by the reaction with ethylamine or propylamine. Based on the NMR data and unique fragmentation patterns produced by these molecules, the sample was identified as 2‐(ethylamino)‐1‐(4‐methylphenyl)‐1‐pentanone, not 4‐methylpentedrone.     

The Impact of Federalism on the Organization of Canadian Foreign Policy

The international activities of Canadian provinces—mainlyAlbert, British Columbia, Ontario, and Québec—challengeconventional concepts of sovereignty and the federal view ofa national monopoly in foreign policy. These provincial activitieshave become more important since the early 1970s and have yieldedoutcomes in the field of foreign policy that would not haveoccurred otherwise. Provinces engage in international activitiesfor a number of reasons. They have the capacity, jurisdictionalobligation, and political desire to do so. Economic necessity,especially the international economic environment, is importantmotivation. Both conflict and cooperation with Ottawa also encourageprovincial involvements in international activities. Occasionally,foreign governments invite such activity as well. Present trendscoupled with the constitutional division of responsibilitiesin Canada suggest that territorial transgovernmentalism willhave greater consequences for Canadian foreign policy, therebygiving to Canada's international presence a character similarto the complexities and contradictions of the country's domesticmosaic.     

Variation of the electorate: Veto and purge

In the paradigm social choice problem, there is a fixed set of alternatives and a fixed set of voters. This essay considers variations of the electorate when some subset of voters has a special voice on some subset of alternatives. We formalized such a situation by means of the veto function. We focus on stable veto functions, exhibit a stable liberal social choice function and promotion mechanism, and investigate a notion of stability for groups whose membership itself is the social state.     

Adolescents’ Experiences of Victimization: The Role of Attribution Style and Generalized Trust

Positive attribution style, negative attribution style, and generalized peer trust beliefs were examined as mediators in the relationship between adolescents’ peer victimization experiences and psychosocial and school adjustment. A total of 280 (150 female and 130 males, M_age = 13 years 4 months, SD_age = 1 year 1 month) adolescents completed measures of peer victimization, global self-worth, depressive symptoms, social confidence, school liking, loneliness, attribution styles, and generalized trust beliefs. Multigroup path analysis revealed that: (a) negative attribution style mediated the relationship between cyber victimization and school liking and depressive symptoms for males and females; (b) positive attribution style mediated the relationship between cyber victimization, school liking, global self-worth, and depressive symptoms for females; and (c) generalized peer trust beliefs mediated the relationship between social victimization, depressive symptoms, social confidence, and loneliness for females. Consequently, attribution style and generalized trust beliefs differentially influence the relationship between peer victimization and adjustment.