Expressions of IL -1α, IL -1β and IL -13 mRNA in Lung Tissue and Serum of Rats Drown in Fresh WaterCSCD

Objective: To detect the changes of (interleukin, IL)-1α, IL-1βand IL-13 mRNA in lung tissue and serum of drown rats, and to explore the potential value for the diagnosis of drowning in forensic practice. Methods: Eighteen SD rats were randomly divided into drowning group, blank control group and myocardial infarction group (as control group). The serum of right ventricular, the inferior lobe of right lung and the myocardium were taken from the rats in different groups. The expressions of IL- 1α, IL-1βand IL-13 mRNA in the lung tissue and the serum of right ventricular were detected by TaqMan probe method. Results: The expression differences of IL-1α, IL-1βand IL-13 mRNA in lung tissue between drowning group and blank control group, myocardial infarction group were not statistically significant (P>0.05). The expression of IL-1βand IL-13 mRNA in serum of right ventricular increased (P<0.05). The expression differences of IL-1α, IL-1βand IL-13 mRNA in serum between blank control group and myocardial infarction group were not statistically significant (P>0.05). Conclusion: The changes of cytokines IL-1βand IL-13 mRNA in the serum of right ventricular of drown rats are statistical significance, which are highly correlated with drowning. © 2018 by the Editorial Department of Journal of Forensic Medicine.     

What Difference Do Polarisation Measures Make? An Application to China

In recent years there has been much discussion of the difference between inequality and polarisation. The vast literature on inequality is held to miss out key features of distributional change, which are better described as changes in polarisation. Axioms have been proposed which capture some of these differences, and measures of polarisation, as distinct from inequality, have been suggested. The theoretical distinctions proposed in this literature are indeed interesting. But do the newly proposed measures of polarisation give different results in comparing societies over time? We address these questions for China, where dramatic increases in inequality and polarisation have been much discussed in the literature. We find that, contrary to theoretical expectation, the new measures of polarisation do not generate very different results from the standard measures of inequality. The paper ends by considering a different approach to polarisation which might better conform to the policy concerns expressed in the specific context of China.     

Information Exchange,Headquarters Economy and Financial Centers Development: Shanghai,Beijing and Hong Kong

Over the past several years, China has consistently maintained economic growth and at the same time emerged as a new global giant in the international arena, despite the distractions caused by the global financial crisis, which was triggered by the US Sub-prime Mortgage Crisis of 2007 and the recent bond crisis that emerged in the European Union in 2011. Concurrent with China's growing interaction with the global economy and robust growth of its domestic economy, competition for the status of national and even international financial centers in the region has become fierce. This study focuses on a ‘local’ examination of internal conditions for the emergence and growth of Chinese financial centers over the next 10–20 years. Cities contending for the top slot in the roster of Chinese cities, like Beijing, Shanghai and Shenzhen, are striving to become international financial centers and are trying to compete with Hong Kong. This study investigates the development potentials, future prospects and division of functions between different financial centers within China regarding Hong Kong, Beijing and Shanghai, with special reference to the role of information and locations of MNCs' regional headquarters.     

Primary study of vascular endothelial growth factor immunohistochemical staining in the diagnosis of early acute myocardial ischemia

The expression of vascular endothelial growth factor (VEGF) in the model of rat early acute myocardial ischemia was studied by Strept-Avidin-Biotin-Peroxidase Complex (SABC) immunohistochemical staining. After ligating the anterior descending branch of the left coronary artery, an initial rapid (30min) positive expression of VEGF in myocardial ischemic areas was observed, the intensity of positive expression of VEGF increased with the continuation of myocardial ischemia. After 5h infarction, the strongly positive myocytes of SABC-VEGF staining were predominantly limited to perimyocardial infarction areas. No positive expression of VEGF was found in the control group. These findings suggested that SABC-VEGF method could give a sensitive, specific, simple and objective morphologic evidence to the diagnosis of sudden cardiac death caused by acute early myocardial ischemia.     

Allele frequencies for nine STR loci in Beijing Chinese

Allele frequencies for nine STR loci namely, D3S1358, HUMvWA, HUMFIBRA/FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820 were obtained from a sample of 198 unrelated Chinese in Beijing, China.     

Yin and Yang: Sina Weibo and the Chinese State

The new element in governance is social media. Inexorably, its fertile networks of shared information shift power from authorities to citizens and amateurs, including to the “unknown” experts in the “dorm rooms and edges of society” who drive innovation. Tweets may bust trust and undermine authority, but can social media also be a tool for building consensus through deliberation and negotiation among interests? When it comes to governance, is crowd‐sourcing any better than populism at generating collective intelligence instead of disruptive “dumb mobs?” Can networks aid the self‐administration of society, or does that take institutions with governing authority? In this section, leading Silicon Valley entrepreneurs, technologists and network theorists from Google, Microsoft and the MIT Media Lab join with political scientist Francis Fukuyama and top thinkers from Asia to address these issues.     

Developing a Spatial-Temporal Method for the Geographic Investigation of Shoeprint Evidence

Abstract:  This article examines the potential of a spatial-temporal method for analysis of forensic shoeprint data. The large volume of shoeprint evidence recovered at crime scenes results in varied success in matching a print to a known shoe type and subsequently linking sets of matched prints to suspected offenders. Unlike DNA and fingerprint data, a major challenge is to reduce the uncertainty in linking sets of matched shoeprints to a suspected serial offender. Shoeprint data for 2004 were imported from the Greater London Metropolitan Area Bigfoot database into a geographic information system, and a spatial-temporal algorithm developed for this project. The results show that by using distance and time constraints interactively, the number of candidate shoeprints that can implicate one or few suspects can be substantially reduced. It concludes that the use of space-time and other ancillary information within a geographic information system can be quite helpful for forensic investigation.     

Determination of drug levels and the effect of diazepam on the growth of necrophagous flies of forensic importance in southeastern Brazil.

Larvae of Chrysomya albiceps (Wiedemann) and Chrysomya putoria (Wiedemann) (Diptera: Calliphoridae) were reared on tissues from rabbits administered twice the lethal dosage of diazepam in order to study the effects of this drug on the development of these two species. The rabbits were given 50mg of diazepam via ear vein infusion. From 18 to 54h, larvae feeding on tissues containing the drug developed more rapidly than larvae from the control colony for both fly species. The time required for pupariation and adult emergence was significantly greater for colony fed on tissues from diazepam dosed rabbits than for the control ones. These differences are significant for they are large enough to alter the estimate of postmortem interval based on fly development. The presence of diazepam could be detected through gas chromatography-mass spectrometer (GC-MS) in all rabbit samples and in almost all diptera samples in this experiment.     

三种方法计算气胸CT影像的肺萎陷程度比较

目的探讨临床经验法、手工边界勾画法和软件自动分析法在基于CT影像的气胸致肺萎陷程度计算上的优劣,从而推荐一种客观科学高效的肺萎陷程度计算方法。方法通过三种方法分别计算54例气胸患者的肺萎陷百分比,比较三种方法在计算效率、结果的相关性、准确性、稳定性等方面的差异。结果临床经验法、软件自动分析法与目前公认的手工边界勾画法的结果间存在线性相关(P<0.01),软件自动分析法的准确性更高;在5级及3级分类法中,三种方法之间存在显著一致性,软件自动分析法与手工边界勾画法在百分比判定上的一致性更好;单侧气胸的肺萎陷百分比的一致率高于双侧气胸;同时,软件自动分析法在计算结果的高效性、稳定性等方面具有优势。结论软件自动分析法可以解决现有CT影像的肺萎陷程度计算方法中效率低和稳定性欠佳的问题,且具有准确性高、可操作性强的特点,适合在法医临床实践中广泛应用。     

论中国实学

本文系统论述了中国实学的内涵及其主流和核心,中国实学的起点和终点,中国实学的现代转化.