Maintaining the high-tech edge: Governmentindustry technology transfer and the federal laboratory system in California

One of the important resources to any state, such as California, is the technology that is available from the many federally operated and/or funded laboratories within its borders. In this age of technology a state needs to take advantage of applications of modern technology and innovative exploitation of human and natural resources. This article illuminates the importance of the Federal Government research laboratories. Many examples are presented to support the argument that the Federal Government research laboratories can be and often are substantial contributors to the storehouse of technology that finds its way to the private sector and public sector. Several types of technology transfer are discussed, i.e. primary technology, secondary applications, mission related, technical assistance and cooperative. In addition the article discusses the structure and logic of the Federal Laboratory Consortium for Technology Transfer (FLC). The legislaltion that has helped to make the FLC effective is discussed. Included in the discussion are insights of how the FLC operates and how the private sector and public sector may use the FLC in order to locate process, product and service technology.     

Reponse to Freeman: the Stony Brook perspective

The author, affiliated with the State University of New York at Stony Brook, responds to John M. Freeman's comments on his medical center's treatment of "Baby Jane Doe." He discloses details of the infant's anomalies not previously available to the public or to Dr. Freeman. Newman defends the prognosis given to Baby Jane's parents by several specialists, and the counseling offered them by professionals familiar with her condition.     

An unusual shotgun injury pattern produced by an intermediate target

Discharge of a shotgun with a shotgun casing in its muzzle as a "dust cover" produced a pattern of injuries suggestive of combined intermediate- and distant-range wounds.     

Spleen and portal lymphnode pathology in fatal drug addiction

Spleen and portal lymphnode sections from 86 drug addicts submitted for medico-legal autopsy at the Institute of Forensic Medicine in Copenhagen in the year 1979 were studied together with tissue sections from 24 "normal" persons. In 70% of the drug addicts the spleen weight was more than 200 g, and in 71% portal lymphnode hyperplasia was found. Birefringent foreign material was found in spleen tissue of drug addicts in 72% and in portal lymphnode tissue in 44%. Signs of antigen stimulation in both spleen and portal lymphnode tissue evaluated by the number of germinal centre and plasma cells were found in more than 80% of the drug addicts compared with about 20% of the "normal" persons. The results were related to anamnestic information of duration of drug abuse, to the spleen weight, to the occurrence of birefringent material and to the liver changes. Examination of lysozyme and immunoglobulin containing cells using the indirect preoxidase technique was performed in a total of 72 cases of spleen tissue, 59 cases of portal lymphnode tissue from drug addicts, 24 cases of spleen tissue and 18 of portal lymphnode tissue from "normal" persons. Lysozyme, IgM and IgG containing cells were found significantly more often among drug addicts than "normal" persons. The results indicate that the splenomegalia and the portal lymphnode hyperplasia often found in drug addicts are caused by continuous antigen stimulation due to repeated injections of various antigens.