Increased risk of fatal intoxication and polypharmacy among psychiatric patients at death

Patients suffering from psychiatric disorders have an excess mortality and a shorter life span expectancy compared to the general population. Furthermore, they are treated with multiple drugs and are known to have an increased risk of drug abuse. In this study, we aimed at investigating the pharmaceutical drug and drug of abuse profiles of the deceased included in the Danish prospective autopsy‐based forensic study on psychiatric patients, SURVIVE. Using the postmortem systematic toxicological analysis results, we identified 129 different consumed compounds in our population (n = 443). Polypharmacy (≥5 compounds) was detected in 39.5% of the deceased. Deceased with a psychiatric diagnosis or who died from a fatal intoxication had significantly more compounds at the time of their death compared to having either no psychiatric diagnosis or another cause of death, respectively. Evidence of drug abuse was present, as 29.8% of our total population had consumed either methadone or illicit drugs of abuse, excluding tetrahydrocannabinol. Of those deceased with a psychiatric diagnosis, 33.6% had either consumed methadone or illicit drugs of abuse, a greater number than those without a psychiatric diagnosis. Fatal intoxication was the most frequent cause of death (40.6%) with methadone as the major intoxicant. Here, we found that those without a psychiatric diagnosis had fewer fatal pharmaceutical drug intoxications compared to the psychiatric diagnosis groups. Our findings add further context to understanding the excess mortality of psychiatric patents, since there is an increased occurrence of fatal intoxication, polypharmacy, and drug abuse in this population.     

Politics and white collar crime: Explaining government intervention in the Savings and Loan Scandal

The Savings and Loan Scandal of the 1980s was the biggest crime ever perpetrated in the United States. While several studies have examined the causes of the crime (e.g., deregulation, increase of insurance coverage to $100,000, fluctuations in the economic markets, greed), few scholars to date have studied state intervention in the industry after the crime had been committed. We explore the questions of when and how state managers intervene in the actions of the powerful by supplementing state theory with the literature on the social construction of social problems. Revised version of a paper presented at the annual meeting of the American Society of Criminology, Miami, November 1994. The authors would like to thank the College of Criminal Justice of Sam Houston State University for financial support in searching newspaper data bases and Henry Pontell for comments on an earlier version of this paper.     

States and Common Pool Resources

The neo-institutionalist theory on the management of common pool resources by states in terms of international regimes is based on dubious assumptions about states as players. If one starts from alternative assumptions about interaction between asymmetrical players and the advantages of opportunistic behaviour, then it is easier to account for the collective action difficulties in a regime such as the Helsinki Commission (HELCOM), which handles the environmental problems in the Baltic Sea region.     

Canada's Foreign Intelligence Interview Program, 1953-90

Canada's Interview Program, established in 1953, was a modest overt human intelligence collector conducting voluntary debriefings of persons with knowledge of ‘denied areas’. Interviews focused on East European industrial capabilities and orders of battle information. Initially housed with intelligence at National Defence, the Interview Program moved to External Affairs in 1968, where it remains.     

Objectives, Characteristics and Outcomes of University Licensing: A Survey of Major U.S. Universities

This paper describes results of our survey of licensing at 62 research universities. We consider ownership, income splits, stage of development, marketing, license policies and characteristics, goals of licensing and the role of the inventor in licensing. Based on these results we analyze the relationship between licensing outcomes and both the objectives of the TTO and the characteristics of the technologies. Patent applications grow one-to-one with disclosures, while sponsored research grows similarly with licenses executed. Royalties are typically larger the higher the quality of the faculty and the higher the fraction of licenses that are executed at latter stages of development. Sponsored research is more likely to be included in a license if the new technology is at an early stage of development or if the TTO evaluates it as important. We find that additional disclosures generate smaller percentage increases in licenses, and those increases in licenses generate smaller percentage increases in royalties.     

First Amendment potluck

This essay argues that the marketplace‐of‐ideas metaphor for law is inadequate to deal with contemporary problems in free expression because many of the entailments of the metaphor are destructive of communication and community. After a review of how metaphors work in the world and the law, the essay reviews the history of the marketplace metaphor, critiques the metaphor and its entailments, and makes a case for a potluck supper metaphor that would be more helpful in resolving contemporary conflicts over freedom of expression.     

DAGGERS,RIFLES AND DYNAMITE: ANARCHIST TERRORISM IN NINETEENTH CENTURY EUROPE

Initially the anarchists did not call for terrorism, but by the 1880s, it erupted as the result of harsh socio-economic conditions in Europe and America, regional and national traditions of social warfare and justified regicide, government repression of more peaceful and organized forms of protest and labor activity, the spellbinding examples of the Paris Commune and the assassination of Tsar Alexander II, the invention of dynamite and anarchist incitement to ‘propaganda by the deed’. These ignited chain reactions of social protest, repression and revenge. While the number of assassinated heads of state and government, and of monarchs of major countries was unprecedented, the anarchists, outside of Spain, killed relatively few people. Nonetheless, the anarchists’ desire for dramatic signs of vindication, the authorities’ and the public's fears of a vast anarchist conspiracy and the media's hunger for sensational news combined to create the mirage of a powerful terrorist movement sweeping through nations and across the world.     

Compelled without direction: Compulsory voting and party system spreading

Much of the current literature on compulsory voting (CV) examines its effects by simulating complete turnout. We argue that these studies do not capture the full effects of CV, as there is something qualitatively different about compulsory voting rules as compared to only increasing turnout. Furthermore, CV and turnout have important, yet unexplored, interactive effects. To test this argument, we look at governments in 43 countries over the 1990–2006 period. Nine of these countries have some form of CV. We examine the effect of CV on the ideological position and range of governments, left party seat share, and the effective number of parties. We find that high turnout in the presence of CV laws spreads out the distribution of voters and leads to an increase in the effective number of parliamentary parties and a larger ideological range of governments. These results have important implications for how we study CV and its consequences for party strategy.     

Esophageal injury in fatal rear-impact collisions

Neck injuries resulting from motor vehicle collisions (MVC), often referred to as whiplash trauma and injury, often demonstrate little or no evidence of significant tissue damage. In rare instances, however, serious injury to the anterior neck organ injuries can result from such trauma. The present study describes esophageal injury associated with rear-impact collisions, based on a unique case report, review of the scientific literature and a query in the National Automotive Sampling System (NASS) database of the US National Highway Traffic Safety Administration. The Medline search and present case study totaled five cases of rear-impact collision-related serious esophageal injury (laceration or rupture). In the four published cases all patients survived, whereas in the presented case study, the patient died due to mediastinitis and sepsis. The NASS query revealed an additional three cases out of a total of 55,926 investigated crashes. All three cases were associated with fatalities. Although no anatomical or bioengineering studies have presented data on the behavior of the esophagus during rear-impact whiplash loading, sudden tensile and/or compressive forces is the likely explanation of injury, often in combination with a local fracture of a vertebral body. In these 8 cases significant esophageal injury carried a substantial (50%) risk of mortality. Clinicians should be aware of the potential for significant complications in the whiplash trauma-exposed patient who complains of chest pain, mid-thoracic pain, discomfort in the neck and throat, respiratory distress, or hoarseness. For those forensic specialists involved in whiplash cases these study results highlight the need to consider esophageal injuries as a rare but potential consequence of whiplash trauma.