Highly sensitive screening method for nitroaromatic, nitramine and nitrate ester explosives by high performance liquid chromatography-atmospheric pressure ionization-mass spectrometry (HPLC-API-MS) in forensic applications

A highly sensitive screening method based on high performance liquid chromatography atmospheric pressure ionization mass spectrometry (HPLC-API-MS) has been developed for the analysis of 21 nitroaromatic, nitramine and nitrate ester explosives, which include the explosives most commonly encountered in forensic science. Two atmospheric pressure ionization (API) methods, atmospheric pressure chemical ionization (APCI) and electrospray ionization (ESI), and various experimental conditions have been applied to allow for the detection of all 21 explosive compounds. The limit of detection (LOD) in the full-scan mode has been found to be 0.012-1.2 ng on column for the screening of most explosives investigated. For nitrobenzene, an LOD of 10 ng was found with the APCI method in the negative mode. Although the detection of nitrobenzene, 2-, 3-, and 4-nitrotoluene is hindered by the difficult ionization of these compounds, we have found that by forming an adduct with glycine, LOD values in the range of 3-16 ng on column can be achieved. Compared with previous screening methods with thermospray ionization, the API method has distinct advantages, including simplicity and stability of the method applied, an extended screening range and a low detection limit for the explosives studied.     

A Dutch perspective: the limits of lawful euthanasia

Dutch author Ubaldus de Vries reviews the current state of the euthanasia law in the Netherlands. The legislation, enacted in 2001, creates a medical exception that allows for euthanasia in cases where patients experience "hopeless and unbearable suffering." A brief history of the Dutch approach to euthanasia is set forth, case law is reviewed, and the unique role of the doctor is examined in seeking to understand the extent of one's right to euthanasia in the Netherlands. Because the courts must determine what constitutes "hopeless and unbearable suffering," Professor de Vries analyzes the judicial interpretation of "suffering" and concludes that judicial interpretation has reached its limits, and thus by implication, the limits of lawful euthanasia have been reached.     

Drinking behavior,drinking attitudes,and attachment relationship of adolescents

In this article the connection between the drinking behavior and drinking attitudes of adolescents in relation to their attachment relationship with their parents is examined. The Family Episode Rating Task (FERT) was used, which was developed to measure the attachment relationship; it measures four patterns of parent-adolescent attachment. An Alcohol Questionnaire was used to measure the quantity and frequency of alcohol use, the amount of problem drinking, and the drinking attitudes of adolescents. It was hypothesized that anxiously attached adolescents have a greater risk of developing damaging drinking habits. One hundred sixty-one adolescents participated, all of them students in Grades 7, 9, and 11 of a high school. By means of an analysis of variance it was demonstrated that the Attitude scale's drinking to facilitate social contact was significantly related to the quality of the attachment relationship with the parents: this reason for drinking was mentioned most frequently among adolescents who were anxiously attached.Received Ph.D. at the same university. Currently studying psychological aspects of excessive alcohol intake.Received Ph.D. at the Catholic University, Nijmegen. Currently involved in stress management training.     

Gelatine lifting, a novel technique for the examination of indented writing

The limitations of the examination of indented writing impressions using electrostatic detection are often paper related. Paper types such as glossy paper, paper of high basis weight, and lithography or gravure-printed papers often give rise to problems resulting in a decrease in sensitivity or a lack of detection altogether. In this paper, a novel technique for the examination of indented writing is presented, which is in a sense complimentary to the technique of electrostatic detection as it is especially suitable for glossy-coated and printed paper types and can in some instances also deal with paper types of higher basis weight. Indented writing grooves will normally contain more particles than the surrounding nonindented areas due to damage of the surface layer resulting in a build-up of filler powder. The method presented uses black gelatine lifter slabs to lift the paper dust image off the surface of the paper. This image can quite easily be photographed using near-to-coaxial lighting. The gelatine lifting method outperforms oblique lighting for the detection of indented writing and is almost as sensitive as electrostatic detection if compared on the types of paper where both perform well. The main advantage of this new technique is, however, that it is especially suitable for those types of paper where electrostatic detection fails and is therefore a welcome addition to the range of methods available to a forensic document examiner for the examination of indented writing.     

Study of the diagnostic value of iron in fresh water drowning

The aim of our study was to test the diagnostic value of iron (Fe) in fresh water drowning by investigating the postmortem levels of hemodilution in drowning cases compared to control cases. Twenty-six typical fresh water drowning cases were selected from 128 immersion cases autopsied in our Department of Forensic Pathology between 1998 and 2004. The exclusion criteria were a long postmortem interval and other causes of death than drowning. For all selected cases, the diagnosis of drowning was based on the presence of autopsy findings and positive diatom test. A control population of 12 cases was also selected. For each drowning and control case, iron blood levels were measured in the left ventricle (LV) and right ventricle (RV) of the heart. The mean difference of iron concentration (RVFe-LVFe) between the drowning group and the control group was statistically compared. Furthermore, iron measurements were performed in 19 drowning cases showing advanced putrefaction. The mean difference of iron concentration was significantly higher in the drowning cases compared with controls (P<0.001). All drowning cases showed hemodilution. No overlap was found in the RVFe-LVFe levels between the two groups. Resuscitation attempts seemed to have no effect on the results. In cases of drowning showing advanced putrefaction, the iron test was not reliable because biochemical iron measurement was often prevented by no sufficient blood in the heart or postmortem clots. In conclusion, according to our results, iron seems to be a good biochemical marker in fresh water drowning with a short postmortem interval.     

Impact of stress and mitigating information on evaluations, attributions, affect, disciplinary choices, and expectations of compliance in mothers at high and low risk for child physical abuse

The objective is to know if high-risk mothers for child physical abuse differ in their evaluations, attributions, negative affect, disciplinary choices for children's behavior, and expectations of compliance. The effect of a stressor and the introduction of mitigating information are analyzed. Forty-seven high-risk and 48 matched low-risk mothers participated in the study. Mothers' information processing and disciplinary choices were examined using six vignettes depicting a child engaging in different transgressions. A four-factor design with repeated measures on the last two factors was used. High-risk mothers reported more hostile intent, global and internal attributions, more use of power assertion discipline, and less induction. A risk group by child transgression interaction and a risk group by mitigating information interaction were found. Results support the social information-processing model of child physical abuse, which suggests that high-risk mothers process child-related information differently and use more power assertive and less inductive disciplinary techniques.     

Harriton, Waller And Australian negligence law: is there a place for wrongful life?

Following the decision by the Supreme Court of New South Wales in Harriton and Waller, the controversial action for wrongful life has been thrown back into the public spotlight. This article examines the legal and public policy dilemmas arising from a wrongful life claim in light of the Court of Appeal's reasons for its decision in the jointly heard cases of Harriton (by her tutor) v Stephens; Waller (by his tutor) v James; Waller (by his tutor) v Hoolahan (2004) 59 NSWLR 694 and analyses whether there is a sound doctrinal basis for recognising the claim within the Australian tort system. It will be argued that each of the legal elements comprising the claim fall squarely within the traditional tort framework and that public policy considerations favouring recognition of the claim outweigh those raised against it.