Observation of tri-allelic patterns in autosomal STRs during routine casework

We report three cases of tri-allelic patterns observed during routine forensic casework on 5964 Belgian residents. These individuals had been typed for the following 15 autosomal STRs: CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, vWA, FGA, TH01, TPOX, D2S1338 and D19S433.The first example of a tri-allelic pattern had the genotype 13;15;16 for the D8S1179 locus. In the second observation there was 16;21;22 pattern for the D18S51 locus. The third case had the alleles 10;11;13 also for D18S51.All cases belonged to the Type I tri-allelic pattern, with three uneven peaks, the sum of the heights of both smaller peaks equalling the height of the tallest peak.Three cases in 5964 typed individuals is a frequency for tri-allelic patterns in autosomal STRs of 0.05%.     

Unusual suicide with a chainsaw

Described here is a case of suicide with the use of a chainsaw. A female suffering from schizophrenia committed suicide by an ingenious use of a chainsaw that resulted in the transection of her cervical spine and spinal cord. The findings of the resulting investigation are described and the mechanism of suicides with the use of a chainsaw is reviewed. A dry bone study was realized to determine the bone sections, the correlation between anatomic lesions and characteristics of chainsaw. The damage of organs and soft tissues is compared according to the kinds of chainsaw used.     

Fatal intoxication due to tramadol alone: case report and review of the literature

Poisoning may also lead to both coma and multiple organ failure, also in youngsters without a known major medical history. As not all toxic agents are routinely screened when a poisoning is suspected, it is useful to consider less frequently encountered poisons in certain cases. We describe the occurrence of asystole and multiple organ failure which occurred in a young man after a suspected tramadol overdose. The tramadol concentration on admission in the ICU was indeed 8 microg/ml (mg/l), far above the therapeutic range. Subsequently, the patient developed severe acute liver failure, finally leading to death. Post-mortem toxicology did not reveal any other poison responsible for this unfavourable course as only very high serum and tissue tramadol and desmethyltramadol concentrations were found. Only a few fatal poisonings attributable to tramadol alone, as observed in our case, have been reported. An overview of these cases is presented.     

新生产力观与可持续发展

可持续发展观是针对传统发展模式的弊端而提出的新发展战略。它要求经济发展与人口、资源和环境相协调,实现人与自然相和谐。新生产力观是可持续发展战略的必然要求,它强调以人为本,人是生产力发展的最终目的,在生产力发展过程中实现人与自然的统一。同时新生产力观也为可持续发展提供智力支持和观念保证。     

Issue yield,campaign communication,and electoral performance: a six-country comparative analysis

Abstract

This article develops and tests a model that explains election outcomes on the basis of party strategy. It employs a new comparative dataset linking representative mass surveys from six European countries with Twitter analysis of campaign activity. The expectation is that parties whose issue agendas exploit electoral opportunities while avoiding risks will be rewarded at the polls. These risks and opportunities are modelled using issue yield, a general framework summarising public support, electoral alignments, and party credibility. Empirically, the article traces a three-step process: (1) the configuration of electoral risks and opportunities (which is captured through public opinion surveys) guides party communication (measured with Twitter data), and to the degree that (2) parties design their campaigns strategically (identified through issue yield), this in turn (3) improves their electoral performance (measured using official statistics). The analysis explains some of the most salient election outcomes of recent years.     

Gas chromatographic-mass spectrometric analysis of buflomedil hydrochloride in biological samples after acute intoxication.

Two cases of acute intoxication of buflomedil hydrochloride are reported. The analysis of this compound was performed by an Extrelut extraction followed by a gas chromatographic-mass spectrometric determination. Analytical parameters of linearity, reproducibility and specificity were satisfactory.     

文化性的缺失—论课程的文化锁定现象

课程起源于化传承的需要，传递、复制、再生产社会化是学校课程唯一不变的使命。在课程发展中形成了特定的化锁定现象。它造成了课程应具有的自的化品性及其所必然引发的内在的、独立的价值标准与宗旨的消解。课程成了现实社会主流化的“代言人”。它具有诠释、粉饰及原样传递的职责，却无反思、批判、创新的品质。学校教育的工具品性、灌输与训练机制、教育教学理论的学术品质等，都是课程化锁定现象所造成的化性缺失的必然结果。揭示课程化性缺失的病理表征，是使课程由化的工具存在转变为化的主体存在的重要前题。