The application of amino acid racemization in the acid soluble fraction of enamel to the estimation of the age of human teeth

The main objectives of the European project "Collaborative Harmonization of Methods for Profiling of Amphetamine Type Stimulants" (CHAMP) funded by the sixth framework programme of the European Commission, included the harmonization of MDMA profiling methods and the creation of a common database in a drug intelligence perspective. In the preliminary stages of this project, the participating laboratories analysed the physical characteristics, the chemical composition and the organic impurities of MDMA tablets, using the previously harmonized methods. The aim of the present work was to apply statistical treatments to the recorded data in order to evaluate their potential in the fight against drug trafficking. Comparable working procedures were applied on the different types of data. The first part of this article deals with organic impurities data, while the second part focuses on the potential of the physical characteristics. Organic impurities data were recorded by a harmonized Gas Chromatography/Mass Spectrometry (GC/MS) method previously developed. Statistical analysis provided a selection of pertinent variables among the 46 organic impurities identified in the chromatograms. Correlation coefficients were used to yield separation between populations of samples coming from the same synthesis batch and samples coming from different batches. It was shown that correlation measurements based on Pearson and cosine functions applied to the data pre-treated by normalisation to the sum of peak responses followed by the square root provided an excellent discrimination between the two populations. The statistical methods applied to organic impurities profiles proved to be excellent techniques to differentiate samples from different batches and to highlight operational links between samples.     

PREVENTION PROGRAMS FOR DIVORCED NONRESIDENT FATHERS

Divorced nonresident fathers are a promising target for preventive efforts to assist families after divorce. The research literature suggests that such programs should focus both on the frequency and the quality of the child's contact with the father, as well as the quality of postdivorce mother–father relations. Dads For Life (DFL) is the program for this target group with the most convincing evidence of preventive effects. This eight-week program centers on professionally made videos. It was tested in a randomized trial with 214 families. In comparison to control families, children in families in which the father participated in DFL had significantly lower internalizing problems. The preventive impact of DFL was strongest for the most troubled youngsters.     

The application of amino acid racemization in the acid soluble fraction of enamel to the estimation of the age of human teeth

Estimation of age-at-death for skeletonised forensic remains is one of the most significant problems in forensic anthropology. The majority of existing morphological and histological techniques are highly inaccurate, and show a bias towards underestimating the age of older individuals. One technique which has been successful in forensic age estimation is amino acid racemization in dentine. However, this method cannot be used on remains where the post-mortem interval is greater than 20 years. An alternative approach is to measure amino acid racemization in dental enamel, which is believed to be more resistant to change post-mortem. The extent of amino acid racemization in the acid soluble fraction of the enamel proteins was determined for modern known age teeth. A strong correlation was observed between the age of the tooth and the extent of racemization. No systematic bias in the direction of age estimation errors was detected. For the majority of teeth analyzed, the presence of dental caries did not affect the results obtained. In a minority of cases, carious teeth showed a higher level of racemization than would be expected given the age of the individual. These results indicate that amino acid racemization in enamel has the potential to be used in age estimation of skeletal remains.     

Correlates of depressive symptoms in adolescents

The relationship between a number of social and cognitive variables and depressive symptomatology was evaluated in a sample of public middle-school and high-school students. The variables measured included stressful life events, locus of control, causal attributions, and means-ends problem-solving abilities. Higher levels of depression were found to be associated with a more external locus of control and a tendency to attribute outcomes to causes which are internal, stable, and global. Parental divorce and socioeconomic status were also found to be associated with higher levels of depression. No relationship was found to exist between either amount of life stress or problem-solving ability and depression. The implications of these results for delineating the underlying dimensions of depression in adolescents are discussed.Previously Dr. Siegel was in the Department of Clinical Psychology at the University of Florida. Received his Ph.D. from Case Western Reserve University in 1975. Major interest is stress reactivity and coping processes in children and adolescents.Clinical psychology intern at the Dallas V.A. Medical Center and doctoral student in clinical psychology at the University of Missouri-Columbia. Major interest is adolescent psychopathology and self-esteem.     

HUNTER‐GATHERER COLLABORATIVE PRACTICE

This article describes the development of a practice group based on a hunter‐gatherer model, with the mission of providing high quality collaborative divorce services, with an emphasis on protecting children and divorcing partners, and expanding access to middle‐ and lower‐income families. The practice group professional disciplines include law, mental health divorce coaching, co‐parent coaching, financial analysis, and case administration. These professionals have collectively associated their individual practices to address challenges facing their collaborative practices. With common purpose, the practice group builds skills, generates client base, nurtures trust, and lays a common knowledge base. Collaborative divorce teams formed from its members serve divorcing families with efficient, cost‐conscious, interest‐based negotiation processes that protect children and help parties productively move on with their lives.     

Long-term intracerebral inflammatory response after traumatic brain injury

Epidemiological and pathological studies suggest that head injury is a significant risk factor for subsequent neurodegeneration and cognitive decline in later life. The precise mechanisms for the development of post-traumatic neurodegenerative change are unclear but we hypothesize that persistence of inflammatory processes in the brain may play a key role and that some individuals are more susceptible to such changes based on their genetic make-up. In support of this hypothesis we present evidence of persistent elevated microglial activity in long-term survivors of head injury and the suggestion of an association between the extent of this activity and interleukin-1 genotype.     

NEGOTIATING TECHNOLOGICAL CHANGE IN THE COMMONWEALTH BANKING CORPORATION

Abstract: In May and June 1981 Automatic Telling Machines (ATMs) were introduced into sixty-one branches of the Commonwealth Banking Corporation in New South Wales, Victoria and the ACT. In contrast to union bans which had been imposed on ATMs in the private banking sector, the Commonwealth Bank Officers' Association (CBOA) actively supported the use of this new technology. After outlining the industry industrial relations system this paper examines the three-way process of negotiations, involving the union, management and the federal government, which led to the introduction of ATMs. The terms of the agreement reached — a 19 day working month, early voluntary retirement after age 55 and a joint consultative committee on technological change in return for supports for ATMs — are analysed and the factors which contributed to the absence of industrial conflict during the negotiations are discussed.