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31.
Recent advances in single nucleotide polymorphisms (SNPs) research have raised the possibility that these markers could replace the forensically established short tandem repeats (STRs). In this work, we compare STRs and SNPs applicability for kinship investigation in terms of expected informative content and probability of occurrence of "difficult cases" (when isolated Mendelian incompatibilities between alleged father and child are found). Since SNPs have a much lower mutation rate than STRs, these difficulties were expected to occur less frequently if SNPs were used instead of STRs. The purpose of this paper is to make some simulations allowing the estimation of how often such difficult cases are expected to occur using both types of markers and how serious can be their impact in routine work. Our results demonstrate that a battery based exclusively on SNPs matching the informative power of current STR kits would be prone, if applied to routine paternity investigation, to the occurrence of cases where the statistical evidence would be inconclusive. We infer that the introduction of a SNP based strategy, as a substitute to the now classical STR approach poses statistical problems that must be carefully evaluated.  相似文献   
32.
Allele frequencies of sixteen autossomal short tandem repeats (STRs), D3S1358, VWA, D16S539, D8S1179, D21S11, D18S51, TH01, FGA, D5S818, D13S317, D7S820, TPOX, CSF1PO, Penta D, Penta E (included in the PowerPlex 16 kit), and the SE33 (PowerPlex ES Monoplex System SE33) were determined in a sample of 200 healthy unrelated individuals from the north of Portugal.  相似文献   
33.
A large body of research clearly demonstrates that adolescents use technology to a staggering degree and that they are one of the main groups that are vulnerable to online victimization. However, the study of cyber-stalking, which is a form of cyber-harassment victimization, has been limited to the adult population and has resulted in some controversy regarding whether fear is a definitional criterion for this phenomenon. In Portugal, the study of cyber-stalking among adolescents is limited, as it is not yet a target of scientific research, public politics or social attention. The current study assessed the cyber-stalking victimization of 627 Portuguese adolescents (12- to 16-years-old). The prevalence of victimization, the cyber-victim’s profile, cyber-stalking dynamics, the cyber-stalker’s profile, parental cyber-involvement and adolescents fear reporting were analysed. The majority of the current sample admitted to having been the victim of cyber-stalking at some point in their life, and nearly half of the adolescents reported experiencing fear after the victimization. A logistic regression model was developed to predict fear reporting. Consistent with previous research, the results indicated that fear is strongly associated with female victims and shed light on the self-perception of online risk and a number of parental involvement practices. Being the target of 1) messages of exaggerated affection, 2) persistent cyber-stalking or 3) older cyber-stalkers was also associated with fear. These results underscore the importance of understanding fear as a complex emotion that results from the interaction of different variables. Thus, it is critical to adopt fear as a key criterion of the cyber-stalking definition. Implications for social, educational, political and judicial practices are also discussed.  相似文献   
34.
Allele frequencies for seven STRs (CD4, CSF1PO, F13A01, FES/FPS, MBPB, TH01, TPOX) were estimated from samples (sized between 300 and 940) of unrelated individuals born in North Portugal.  相似文献   
35.
Self‐embedding behavior (SEB) is the repeated insertion of sharp objects, such as needles or pins, into the soft tissues of abdomen, limbs, and other body parts. In this study, two cases of SEB were reported and the scientific worldwide literature reviewed. Thirty‐two cases of SEB were identified through systematic searches in the main bibliographic databases. Mean age was 35 years (SD = 8.97). Just over two‐thirds of the patients were female. Although the number of embedded objects could be as high as 200, major clinical and surgical complications were uncommon and mortality was null. Patients with SEB presented three major diagnoses: psychotic (25%), personality (21.9%), and factitious (28.1%) disorders. The practice of SEB largely went undetected as the patients themselves did not bring it to the attention of family members or physicians and usually denied they have engaged in SEB. A high level of suspicion is required to avoid a missed diagnosis.  相似文献   
36.
The impact of phylogeographic information on mtDNA forensics has been limited to the quality control of published sequences and databases. In this work we use the information already available on Eurasian mtDNA phylogeography to guide the choice of coding-region SNPs for haplogroup H. This sub-typing is particularly important in forensics since, even when sequencing both HVRI and HVRII, the discriminating power is low in some Eurasian populations. We show that a small set (eight) of coding-region SNPs resolves a substantial proportion of the identical haplotypes, as defined by control-region variation alone. Moreover, this SNP set, while substantially increasing the discriminating efficiency in most Eurasian populations by roughly equal amounts, discloses population-specific profiles.  相似文献   
37.
38.
Schumpeterian growth theory stresses the role of structural change in long run growth. Countries which increase the share of technology-intensive sectors in their economic structures benefit more from technological learning and innovation. In addition, they are more able to respond to changes in the international markets and to compete in sectors whose demand grows at higher rates. The paper compares Brazil (and to a lesser extent the CIBS group of countries) from the point of view of the direction and intensity of structural change. It is suggested that structural change has been relatively weak in Brazil and that this has been associated with a less dynamic growth performance since the 1980s.  相似文献   
39.
The Parceria (Partnership) Project is a Brazilian intervention program designed for mothers with an intimate partner violence (IPV) history. Its short term goal is to teach parenting skills to abused women, and in the long term, to prevent behavioral problems in their children. The objective of this pilot study was to evaluate the feasibility of the Parceria Project with mothers of children who had experienced multiple forms of maltreatment (poly-victimization), as it was expected that most of the mothers would also have a history of IPV. Seventeen Brazilian mothers took part in this intervention. They completed several types of evaluation. The intervention program using a cognitive-behavioral model took place in each family’s home. All mothers completed the intervention and evaluated the project positively. The study showed that it is feasible to conduct interventions with families who face severe psychosocial risk such as family violence.  相似文献   
40.
The government of Fernando Henrique Cardoso (1995–2002) redistributed a surprising amount of land to Brazil's landless. Assessing that reform, this study argues that an adequate appreciation of land redistribution must transcend the debate about the number of beneficiaries and place the reform in the larger context of state policies toward land and agriculture. It then asks to what extent such policies under Cardoso represented the dismantling of past state practices in the countryside. Although the Cardoso administration enacted some significant and democratizing changes, it missed other opportunities to benefit the rural poor, and its policies essentially maintained the agricultural model of the past two decades.  相似文献   
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