Cocaine and benzoylecgonine excretion in humans.

Maximal urinary excretion of unchanged cocaine occurred within 2 h of the intranasal absorption of 1.5 mg/kg body weight of cocaine hydrochloride, and diminished rapidly thereafter. Excretion of benzoylecgonine was maximal 4 to 8 h following administration of the drug and diminished slowly over an interval of several days. Peak cocaine and benzoylecgonine concentrations observed were 24 and 75 microgram/ml, respectively. Benzoylecgonine/cocaine ratios were too varied to allow estimation of cocaine concentrations from benzoylecgonine concentration data or vice versa. Benzoylecgonine concentrations generally exceeded the corresponding cocaine values by a wide margin, but excretion of free cocaine in the absence of benzoylecgonine was observed in one subject. Cocaine was generally detected for only approximately 8 h, and for a maximum of 12 h, whereas benzoylecgonine was generally detected by chromatographic or enzyme immunologic assays for 48 to 72 h. Benzoylecgonine was positively identified in urine by raidoimmunoassay for 96 to 144 h after dosing.     

The war‐making state and privatisation

States, created with the central purpose of defending national independence, resist the process of macro‐economic reform since it appears to limit their power to pursue this aim. The states of the former Centrally Planned Economies were marked out by their extreme subordination to the military drive, so the resistance to reshaping the ‘war‐making state’ into a ‘market‐facilitating state’ is considerable. The transition tends to be halted where the old structures of central control are ended without markets supplying alternative imperatives — a ‘rent‐seeking state’ is created. These themes are examined in relationship to privatisation of state owned enterprises in four countries: Russia, China, Vietnam and the Ukraine.     

Issues of fairness in recruitment processes: A case study of local government practice

Since the 1980s local government recruitment practices have been characterised by the development of procedures designed to promote fairness in employee selection. This article examines recruitment practice in one local authority in terms of its effectiveness in providing fairness in selection and questions its ability to meet the changing demands being placed on recruitment processes. A central argument is that an emphasis on developing recruitment procedures to demonstrate equality of treatment can overlook important social psychological factors. It concludes that although a highly structured approach to employee selection has real advantages in meeting the requirements of equal opportunities it can, paradoxically, result in negative perceptions about its fairness and effectiveness.     

Support and Opposition for Invading Iraq: Did the President's Speech Make a Difference?

Utilizing data from the annual San Antonio Survey, this research addresses the issue of support and opposition to invading Iraq among respondents randomly selected from Bexar County, Texas. Data were collected prior to and after President Bush addressed the nation on October 7, 2002, seeking broad citizen support for his plan, allowing us to ascertain whether or not his speech impacted the attitudes of potential voters. Our results indicate that the President's speech, along with the extensive media coverage about it, was effective in gaining support for his proposal to invade Iraq. A multivariate logistic regression analysis also displayed that the speech still had a significant impact even after controlling for confidence in the president, political orientation, race, ethnicity, nativity, and socio-demographic context. The findings suggest support for earlier research indicating that the impact of presidential speeches could boost the approval of a policy, in particular, if the speech occurred during his first term of office, was considered a “major” speech, was devoted to one important topic, and its primary focus was on foreign policy. Under these conditions, such a speech portrays the president as a strong leader.