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排序方式: 共有755条查询结果,搜索用时 15 毫秒
131.
In this paper, we evaluate the effects of a large-scale and continuing place-based policy in China. In 1994, the Chinese central government designated 592 counties as National Poor Counties (NPC), which have been receiving preferential treatment in several aspects. Our identification strategy exploits a discontinuous criterion for determining a county’s eligibility of the programme. We find that the NPC programme failed to foster local economic growth. Further investigation suggests that local capture is partly responsible for this failure. Our findings yield important policy implications that, in countries with limited local accountability, place-based policies characterised by decentralised implementation are not always a blessing. 相似文献
132.
Allele frequencies of 10 STR loci in Koreans 总被引:1,自引:0,他引:1
Allele frequencies for the 10 STR loci, D6S1043, D9S925, D7S821, D4S2368, D21S2055, GATA193A07, D12S391, D10S2326, D15S822 and D18S51 were obtained from a sample of 217-310 unrelated Koreans. In this study, 2 out of the 10 loci did not meet Hardy-Weinberg expectation. The combined probability of identity for 10 loci tested was 4.93 x 10(-14). 相似文献
133.
Chang Hua Wong Seok Hwee Koo George Qiongze She Paul Chui Edmund Jon Deoon Lee 《Forensic Science International Supplement Series》2009,192(1-3):53-55
We analyzed the coding regions of the cardiac calcium-handling genes, ryanodine receptor 2 (RyR2) and calsequestrin 2 (CASQ2) for genetic variants in a healthy Chinese population (n = 95) and in a cohort of 28 sudden unexplained death victims. Mutations in RyR2 and CASQ2 have been shown to alter calcium homeostasis during excitation–contraction coupling and predispose individuals to fatal cardiac arrhythmias. The genetic screening was accomplished by denaturing high-performance liquid chromatography and DNA sequencing methods. Genetic analysis revealed the following non-synonymous genetic variations: two reported RyR2 polymorphisms; 5654G>A (G1885E) and 5656G>A (G1886S), two reported CASQ2 polymorphisms; 196A>G (T66A) and 226G>A (V76M) and one novel CASQ2 mutation; 529G>C (E177Q). The functional significance of the novel CASQ2 mutation has not been evaluated and characterized. This study shows that multiple genetic variations of the RyR2 and CASQ2 genes exist in the two study populations. The inter-individual genetic variability may underlie the different susceptibility of individuals to developing ventricular tachycardia. The research results will be valuable for which future work involving clinical and forensic samples can be based upon to distinguish potential disease-associated mutations from common polymorphisms. 相似文献
134.
Dennis Y. Wang Chien-Wei Chang Nicola J. Oldroyd Lori K. Hennessy 《Forensic Science International: Genetics Supplement Series》2009,2(1):113-114
Forensic databasing laboratories routinely analyze blood or buccal cell samples deposited on FTA® paper. Prior to PCR amplification of the STRs, the FTA® samples must undergo multi-step sample purification protocols to remove the PCR inhibitors present within the sample and from the FTA® paper. The multi-step sample purification protocols are laborious, time-consuming and increase the potential for sample cross-contamination.To eliminate the need for DNA purification, we conducted studies to optimize the PCR buffer and thermal cycling parameters to allow for direct amplification of STRs from blood or buccal samples on FTA® paper. We evaluated the effect of various factors on the DNA profile including: FTA® disc size, blood sample load variation, and buffer formulation. The new STR assay enables the direct amplification of DNA from single source samples on FTA® discs without sample purification. The new STR assay improves the workflow by eliminating tedious steps and minimizing sample handling. Furthermore, the new STR assay reduces cost by eliminating the need for purification reagents and expensive robots. 相似文献
135.
我国收入分配差距快速扩大问题探析 总被引:2,自引:0,他引:2
收入分配差距过大,不利于经济发展与消费增长,影响民族团结,动摇党的执政基础,增加改革的成本,引发信仰危机.政府须加快税法建设,调节高收入;加快工资制度改革,扩大中等收入阶层;加快法律制度建设,取缔非法收入;加快取消束缚农民的制度,加大对农民、农业、农村的支持力度.加快调整财政支出结构,增加社会保障支出;加快市场法制化规则化,完善市场体系等,以缩小收入分配差距,促进社会和谐. 相似文献
136.
论已确认事实的预决力 总被引:1,自引:0,他引:1
已确认事实的预决力既不同于裁判的既判力,也有别于"争点效"和"争点排除规则",其是我国民事诉讼法确立的一项具有独特内涵的制度。然而,由于我国民事诉讼法未明确预决力的条件和范围,从而致使司法实践中法院的做法各不相同,这种状况一方面有损法院判决的一致性、权威性,也与确立预决力制度的初衷相违背,因此,民事诉讼法的修改应明确预决力的条件和范围。实践中,法院应根据已确认事实的不同具体认定其不同的预决力。 相似文献
137.
Yung-Po Liaw Po-Wen Wang Chiu-Chin Huang Chia-Ming Chang Wen-Chung Lee 《Journal of forensic sciences》2008,53(1):199-202
The paper aims to show the different suicide mortality rate between 1997-1998 and 2000-2001 in Nantou County of Taiwan with earthquake on September 21 (often referred to as the "9-21 earthquake") in 1999. In additional, it also identifies the preventive strategies for the high-risk suicide population. The age-standardized mortality rates for suicide in Nantou County were calculated for the years 1997-1998 and 2000-2001. The suicide standardized mortality ratio (SMR for townships in Nantou were calculated by "type of township" as the standard rate). There is a statistically significant difference in male suicide rates for the years prior to the earthquake (1997-1998) when pooled and compared to the suicide rates for the years after the earthquake (2000-2001). The rate for four age groups (under 25, 25-44, 45-64, 65 and above) all increased, yet all but one (the group of age 45-64) was not statistically significant. The male SMR has slightly increased after the 9-21 earthquake. Yet there are no statistical significances in most townships, except in Kaohsiung and Puli after the 9-21 earthquake. The Kaohsiung SMRs were 1.36 (95% CI: 0.54-2.80) before the earthquake (1997-1998) and 2.01 (95% CI: 1.04-3.52) after the earthquake (2000-2001). The SMRs before and after the earthquake in the Puli Township were 1.51 (95% CI: 0.95-2.29) to 1.56 (95% CI: 1.03-2.27). This study suggests that monitoring high-risk population, especially males or 45-64 years of age who experienced the highest statistically significant suicide rate in this study. The study provides support for providing both the psychological restoration program and, to the extent feasible, financial support for the unemployed as useful public health strategies for suicide prevention in Taiwan. 相似文献
138.
目的为了得到可经载体连接表达、并只由抗体可变区构成的单链抗体基因而进行本实验.方法经扩增得到的鼠抗人转铁蛋白抗体轻、重链可变区基因经凝胶电泳分离、离心柱纯化及定量,同能柔性折叠的一段短连接肽基因一起进行扩增拼接反应,而后在含限切酶位点的引物指导下扩增引入限切酶SfiI和NotI的酶切位点识别序列,产物以电泳鉴定、纯化和定量,再分别用SfiI和NotI酶切消化,最后再柱纯化.结果得到了携带可与载体连接的粘性末端的鼠抗人转铁蛋白单链抗体基因.结论两个不同的基因通过两端含互补序列的第三个基因片断可只经过扩增而无需DNA连接酶的作用而连接起来.对于抗体基因可由此而产生新的轻重链基因的组合,有可能产生性能更优异的抗体. 相似文献
139.
改革完善党的执政体制是一项艰巨复杂的系统工程。在我国现实国情、党情条件下,党的执政体制构成国家政治体制的核心与支柱。执政体制改革本质上是社会主义政治制度的自我完善。必须坚持以马列主义、毛泽东思想、邓小平理论和"三个代表"重要思想为指导,全面贯彻落实科学发展观,按照科学执政、民主执政、依法执政的目标和要求,自觉探讨共产党执政规律,直面现实、勇于创新,积极稳妥地改革完善党的执政体制。 相似文献
140.
常艳 《国家检察官学院学报》2008,16(6):56-60
法的价值是法和法律制度的重要因素和特质,也是法学理论中的难点问题.法律实践和法学理论的许多同题都需要研究法的价值问题,而法的价值的研究方法制约着法的价值研究的深入.只有通过认识主体与客体之阃的关系,坚持主体需要的客观性、阶级性和社会性,采用从主体需要入手的方法,才能正确认识和诠释法的价值问题. 相似文献