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571.
Wyman JF Dean DE Yinger R Simmons A Brobst D Bissell M Silveira F Kelly N Shott R Ohr J Howard R Lewis B 《Journal of forensic sciences》2011,56(3):694-699
Drug levels in decomposed individuals are difficult to interpret. Concentrations of 16 drugs were monitored in tissues (blood, brain, liver, kidney, muscle, and soil) from decomposing pigs for 1 week. Pigs were divided into groups (n = 5) with each group receiving four drugs. Drug cocktails were prepared from pharmaceutical formulations. Intracardiac pentobarbital sacrifice was 4 h after dosing, with tissue collection at 4, 24, 48, 96, and 168 h postdosing. Samples were frozen until assay. Detection and quantitation of drugs were through solid phase extraction followed by gas chromatograph/mass spectrometer analysis. Brain and kidneys were not available after 48 h; liver and muscle persisted for 1 week. Concentration of drugs increased during decomposition. During 1 week of decomposition, muscle showed average levels increasing but concentrations in liver were increased many fold, compared to muscle. Attempting to interpret drug levels in decomposed bodies may lead to incorrect conclusions about cause and manner of death. 相似文献
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Like dispute resolution practitioners in other arenas, organizational ombudspeople face profound challenges in dealing with the issue of neutrality. For ombuds, it is useful to view neutrality as composed of three major dimensions: the definition or terms of reference for the position; its institutional location; and the interactions of the ombuds within the organization. The authors analyze each of these conditions, and offer advice on how ombudspeople can maintain and enhance their neutrality. 相似文献
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Can Physician-Assisted Suicide Be Regulated Effectively? 总被引:1,自引:0,他引:1