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Pregnancy among adolescents, and especially among low-income adolescents, represents a high-risk situation from multiple points of view. When compared to data for the population at large, obstetrical outcome is worsened, subsequent educational attainment is poor, social prognosis is guarded, and repeat unwanted pregnancies are common. The surviving infants, similarly have relatively high incidences of medical and developmental problems. In recent years, comprehensive interdisciplinary programs have been organized to offer more meaningful help to these individuals. The present report describes the authors' 5-year experience with one early intensive program. Considerable medical, educational, and social successes have been noted. The results are especially striking when contrasted with the authors' current experience with an improving but still more fragmented and less successful program. Findings concerning infant development and the mother-infant interaction are also noted. Finally, issues related to the achievement of successes and the persistence of problems after provision of more adequate comprehensive services are discussed.This study was supported in part by Grant No. 03-H-000-079-03-0, Maternal and Child Health Service, H.S.M.H.A., H.E.W.While on the faculty of the State University of New York, College of Medicine at Syracuse, was a founder and the first medical director of the YMED program.Specialty is Developmental Psychology, and research interests concern infant and early child development and the effects of children on parents. While on the faculty of Cornell University, served as a consultant to the YMED program.Project director of the high-risk program.While on the faculty of the State University of New York, College of Medicine at Syracuse, was obstetrical director of the YMED program.  相似文献   
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Noonan D 《Newsweek》2000,136(13):22-30
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Three homicides and one attempted homicide by choking in which apparent signs of throttling were present on the skin of the neck are described. The victims wore slender necklaces which were pressed against the skin by the hands of the perpetrator, causing transverse hematomas and cutaneous abrasions. The following criterious are typical for simulated signs of throttling: similarity to objects on the neck, incomplete course around the neck, absence of coarctation of the soft tissues, no lesions of subcutaneous structures.  相似文献   
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We describe a method for obtaining specific and reproducible deoxyribonuclease I (DNase I) typing from liquid semen. Isoelectric focusing of the enzymes on polyacrylamide gel (IEF-PAGE, pH 3.5-5) was accomplished using a 0.5-mm thick gel. The separated isozymes were visualized by a new activity staining method, dried agarose film-overlay (DAFO). Pretreatment of semen samples with neuraminidase markedly enhanced the isozyme-band resolution and sensitivity. The method was simple and reliable, with high resolution and sensitivity. The DNase I types in semen samples were correlated with the types found in corresponding blood and urine samples. DNase I typing could therefore provide an additional discriminant characteristic in the forensic examination of semen.  相似文献   
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