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31.
George Anderson 《Canadian public administration. Administration publique du Canada》1996,39(4):469-488
Abstract: Senior officials in the federal public service are giving new attention to the need to strengthen policy capacity and this article draws heavily on the work of a task force of federal officials. Four themes run through the article: there is a strong, but neglected, managerial dimension to policy work; the greatest weakness in the current system is dealing with longer-term and strategic issues, especially of a horizontal nature; policy managers need to pay more attention to how to work with and support the external policy community; leadership at the most senior levels of the public service is critical for strengthening policy capacity. Policy management within departments is examined in terms of seven broad policy functions and organizational arrangements. Policy management across government is examined in terms of the role of central agencies and the special problems of horizontal coordination, including the conditions promoting coordination and the machinery of interdepartmental relations. The importance of the personnel dimension of policy work is underlined, with consideration of policy generalists, policy managers and policy specialists. Finally, relations with the policy research community and the provinces are examined. Sommaire: Les dirigeants de la Fonction publique fédérale s'intéressent davantage maintenant à la nécessité de renforcer la capacité d'élaboration des politiques, et le présent article s'appuie largement sur les travaux d'un groupe de travail composé de fonctionnaires. L'article illustre quatre thèmes: le travail d'élaboration de politiques comporte un aspect de gestion très marqué, mais négligé; la plus grande faiblesse du système actuel réside dans sa façon d'aborder les questions stratégiques et à long terme, surtout celles de nature horizontale; il faut que les administrateurs de politiques cherchent davantage à collaborer avec les organes délibérants extérieurs et à leur fournir leur appui; il incombe aux plus hauts dirigeants de la Fonction publique d'avoir le leadership si Ton veut renforcer la capacité d'élaboration de politiques. On examine la gestion des politiques dans les ministères par rapport à sept grandes fonctions des politiques et aux arrangements organisationnels. On étudie la gestion des politiques dans tout le gouvernement en fonction du rôle des organismes centraux et des problèmes particuliers de la coordination horizontale, notamment les conditions favorables à la coordination et le mécanisme des relations interministérielles. On souligne l'importance de l'aspect personnel dans le travail d'élaboration et on mentionne les généralistes, les administrateurs et les spécialistes des politiques. On aborde pour finir les relations avec le milieu de la recherche sur les politiques et avec les provinces. 相似文献
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Validation of a 16-locus fluorescent multiplex system 总被引:24,自引:0,他引:24
Krenke BE Tereba A Anderson SJ Buel E Culhane S Finis CJ Tomsey CS Zachetti JM Masibay A Rabbach DR Amiott EA Sprecher CJ 《Journal of forensic sciences》2002,47(4):773-785
STR multiplexes have been indispensable for the efficient genotyping of forensic samples. The PowerPlex 16 System contains the coreCODIS loci, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, CSF1PO, FGA, THOI, TPOX, vWA, the sex determinant locus, amelogenin, and two pentanucleotide STR loci, Penta D and Penta E. This multiplex satisfies the locus requirements for most national databases and is the most efficient currently available system due to its single PCR amplification. To provide the groundwork for judicial acceptance, including the publication of primer sequences, and to evaluate laboratory-to-laboratory variation, a developmental validation for casework on this commercially available system was performed in 24 laboratories and produced the following conclusions. Amplification was reliable on a variety of thermal cyclers and product could be analyzed on either an ABI PRISM 310 Genetic Analyzer or an ABI PRISM 377 DNA Sequencer. Genotyping using single source samples was consistent between 0.25 and 2 ng of input DNA template with a few laboratories obtaining complete genotypes at 0.0625 ng. However, heterozygote allele imbalance (<60% peak height balance) caused by stochastic effects was observed at a rate of 13% with 0.125 ng DNA and 22% at 0.0625 ng DNA. Mixture analyses were done using a total of 1 ng of DNA template. Most alleles were detected in mixtures of 4 to 1 and some minor alleles were detected in mixtures of 19 to 1. Optimum amplification cycle number was dependent on the sensitivity of the detection instrument used and could also be adjusted to accommodate larger amounts of DNA on solid supports such as FTA paper. Reaction conditions including volume, annealing temperature, and concentrations of primer, AmpliTaq Gold, and magnesium were shown to be optimal yet robust enough to withstand moderate variations without affecting genotype analysis. Environmental, matrix and standard source analyses revealed an ability to obtain complete genotypes in all sample types except those exposed to 80 degrees C for 12-48 days. Finally, comparison of genotype results from the PowerPlex 16 System with other commercially available systems on non-probative reference and forensic samples showed consistent results. 相似文献
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This paper examines a number of demographic aspects in congressional districts and states that played important roles in a series of Congressional votes on environmental issues in 2000. These characteristics include urbanization or population density, education, income, race, and employment. Our findings are mixed. While we find some evidence (at least in Senate votes) that population density is a positive predictor of “pro-environment” votes, we also find that things commensurate with the Environmental Kuznets Curve such as income, education, and lifestyle also play an important role in environmental voting. 相似文献
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The purpose of the pilot study was to examine the interrelationship between social support, risk-level, and safety actions for 2 groups of suicidal adolescents (50 attempters and 50 ideators), who had presented for an acute assessment at an outpatient mental health service. A social support model was proposed in which it was thought that information related to patients' social support would impact upon the types of risk-level and safety actions made by clinicians. Data was collected from a total of 100 patient files, utilizing the acute assessment reports (e.g., reports assessing risk of self-harm). Findings show that groups differed significantly on indices of negative support severity, positive support, and risk-level. Limited support was found for the proposed social support model. Limitations and implications for future research are discussed. 相似文献
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