Partial Agonist Therapy in Schizophrenia: Relevance to Diminished Criminal Responsibility

Abstract: Pathological gambling (PG), classified in the DSM‐IV among impulse control disorders, is defined as inappropriate, persistent gaming for money with serious personal, family, and social consequences. Offenses are frequently committed to obtain money for gambling. Pathological gambling, a planned and structured behavioral disorder, has often been described as a complication of dopamine agonist treatment in patients with Parkinson’s disease. It has never been described in patients with schizophrenia receiving dopamine agonists. We present two patients with schizophrenia, previously treated with antipsychotic drugs without any suggestion of PG, who a short time after starting aripiprazole, a dopamine partial agonist, developed PG and criminal behavior, which totally resolved when aripiprazole was discontinued. Based on recent advances in research on PG and adverse drug reactions to dopamine agonists in Parkinson’s disease, we postulate a link between aripiprazole and PG in both our patients with schizophrenia and raise the question of criminal responsibility.     

Classification Improvements in Automated Gunshot Residue (GSR) Scans

Classification of particles as gunshot residues (GSRs) is conducted using a semiautomatic approach in which the system first classifies particles based on an automatic elemental analysis, and then, examiners manually analyze particles having compositions which are characteristic of or consistent with GSRs. Analyzing all the particles in the second stage is time consuming with many particles classified by the initial automated system as being potentially GSRs excluded as such by the forensic examiner. In this paper, a new algorithm is developed to improve the initial classification step. The algorithm is based on a binary tree that was trained on almost 16,000 particles from 43 stubs used to sample hands of suspects. The classification algorithm was tested on 5,900 particles from 23 independent stubs and performed very well in terms of false positive and false negative rates. A routine use of the new algorithm can reduce significantly the analysis time of GSRs.     

A social and political profile of Canadian legislators, 1996

This research note provides an overview and an update on the social and political backgrounds of all elected Canadian legislators at the federal and provincial/territorial levels of government in 1996. For provincial/territorial legislators data are presented by electoral jurisdiction, and for all legislators by level of government and political party. Relatively few differences in social characteristics were found between the two levels although there were some variations by province, territory and party. Business, education and law are the three most prevalent occupations, although the latter has declined among legislators over time. There is little movement of members from the provincial to the federal level. The most common political experience of both groups lies in municipal governance. Over time women have increased their share of seats at both levels. Even in a polity such as Canada with high rates of legislative turnover at both federal and provincial/territorial levels and with new parties emerging, most changes in social and political experience backgrounds proceed incrementally.     

Books received

Dependency under Challenge: The Political Economy of the Commonwealth Caribbean. Edited by Anthony Payne and Paul Sutton. Manchester: Manchester University Press, 1984. Pp.xii + 294. £25. ISBN 0 7190 0970 7.

The International Crisis in the Caribbean. By Anthony Payne. London: Croom Helm, 1984. Pp.iii + 177. £14.95. ISBN 0 7099 2052 0.

Grenada: Revolution and Invasion. By Anthony Payne, Paul Sutton and Tony Thorndike. London: Croom Helm, 1984. Pp.x + 233. £17.95. ISBN 0 7099 2080 6.

The Three Worlds: Culture and World Development. By Peter Worsley. London: Weidenfeld &; Nicolson, 1984. Pp.xiv + 409. £16.95 and £8.95. ISBN 0 297 783467 and 78356 4.

Agriculture, Poverty and Freedom in Developing Countries. By Eric Clayton. London: Macmillan, 1984. Pp.x + 277. £15 and £6.95. ISBN 0 333 36100 8 and 36101 6.

Understanding Green Revolutions: Agrarian Change and Development Planning in South Asia. Edited by Tim P. Bayliss‐Smith and Sudhir Wanmali. Cambridge: Cambridge University Press, 1984. Pp. x + 384. £30/$59.50. ISBN 0 521 24942 2.

Kritsman and the Agrarian Marxists. Edited by Terry Cox and Gary Littlejohn. London: Frank Cass, 1984. Pp. 149. £18.50. ISBN 0 7146 3237 6.

The Defense of Community in Peru's Central Highlands: Peasant Struggle and Capitalist Transition, 1860–1940. By Florencia E. Mallon. Princeton, NJ: Princeton University Press, 1983. Pp. xiv + 384. £28.20 and £12.60. ISBN 0 691 07647 2 and 10140; X.

Miners, Peasants and Entrepreneurs: Regional Development in the Central Highlands of Peru. By Norman Long and Bryan Roberts. Cambridge: Cambridge University Press, 1984. Pp.x + 288. £25. ISBN 0 521 24809 4.

The New Bourgeoisie and the Limits of Dependency: Mining, Class and Power in ‘Revolutionary’ Peru. By David G. Becker. Princeton, NJ: Princeton University Press, 1983. Pp.xxviii + 368. £30.20 and £8.60. ISBN 0 691 07645 6 and 0 691 02213 5.

The Pharmaceutical Industry and Dependency in the Third World. By Gary Gereffi. Princeton, NJ: Princeton University Press, 1983. Pp.xiii + 292. £21.60 and £8.65. IBSN 0 691 09401 2 and 02828 1.

Law and Policy of Producers’ Associations. By D.E. Pollard. Oxford: Clarendon Press, 1984. Pp.xii + 372. £30. ISBN 0 19 825480 6.

Inequalising Trade? A Study of Traditional North/South Specialisation in the Context of Terms of Trade Concepts. By John Spraos. Oxford: Clarendon Press in cooperation with UNCTAD, 1983. Pp.ix + 169. £15. ISBN 0 19 828458 6.

Reality and Rhetoric: Studies in the Economics of Development. By P. T. Bauer. London: Weidenfeld &; Nicolson, 1984. Pp.viii + 184. £11.95. ISBN 0 297 78335 1.

Critique and Anti‐Critique: Essays on Dependence and Reformism. By Andre Gunder Frank. London: Macmillan, 1984. Pp.xiii + 336. £20 and £7.95. ISBN 0333 37122 4 and 37123 2.

Participation of the Poor in Development. Edited by Benno Galjart and Dieke Buijs. Leiden: Leiden Development Studies No.2, 1982. Pp.325. NP.

Studies in Rural Participation. Edited by Amit Bhaduri and Md. Anisur Rahman. New Delhi: Oxford &; IBH Publishing Co., 1982. Pp. vii + 229. Rs.85.

Evaluating Population Programs: International Experience with Cost‐effective Analysis and Cost‐benefit Analysis. Edited by Ismail Sirageldin, David Salkever and Richard W. Osborn. London: Croom Helm; New York: St. Martin's Press, 1983. Pp.xxxi + 534. £19.95. ISBN 0 7099 2393 7.

Development Planning Models. Edited by S. Bhagwan Dahiya. 2 vols. New Delhi: Inter‐India Publications, 1982. Pp.xxiv + 392 + xxiv + 270. $60 the set.

Appropriate Products, Employment and Technology: Case‐Studies on Consumer Choice and Basic Needs in Developing Countries. Edited by Wouter van Ginneken and Christopher Baron. London: Macmillan, 1984. Pp. xi + 260. £25. ISBN 0 333 35302 1.

Education and Income Determination in Kenya. By Arne Bigsten. Aldershot, Hants: Gower, 1984. Pp.vii + 156. £14.50. ISBN 0 566 00703 7.

The Impending Crisis in Kenya: The Case for Land Reform. By Diana Hunt. Aldershot, Hants: Gower, 1984. Pp.viii + 314. £17.50. ISBN 0 566 00713 4.

Ibn Khaldun: The Birth of History and the Past of the Third World. By Yves Lacoste. London: New Left Books and Verso, 1984. Pp. 214. £20 and £5.95. ISBN 0 86091 084 9 and 789 4.     

Policy entrepreneurs and post-conflict cross-border cooperation: a conceptual framework and the Israeli–Jordanian case

What is the role of policy entrepreneurs in shaping the dynamics which normalize relationships between neighboring countries after the formal resolution of conflict? This article suggests a conceptual framework to understand the influence of policy entrepreneurs on public policy regarding cross-border interaction in post-conflict border regions. We analyze the motivations, preferences and strategies of local players which design given realities in the border region. We propose a typology of the various policy entrepreneurs active in the post-conflict border region. The theoretical framework is used in the analysis of the Israeli–Jordanian border region since the peace treaty of 1994.     

Waging War on Poverty: Poverty Trends Using a Historical Supplemental Poverty Measure

Using data from the Consumer Expenditure Survey and the March Current Population Survey, we provide poverty estimates for 1967 to 2012 based on a historical supplemental poverty measure (SPM). During this period, poverty, as officially measured, has stagnated. However, the official poverty measure (OPM) does not account for the effect of near‐cash transfers on the financial resources available to families, an important omission since such transfers have become an increasingly important part of government antipoverty policy. Applying the historical SPM, which does count such transfers, we find that trends in poverty have been more favorable than the OPM suggests and that government policies have played an important and growing role in reducing poverty—a role that is not evident when the OPM is used to assess poverty. We also find that government programs have played a particularly important role in alleviating child poverty and deep poverty, especially during economic downturns.     

Regret,Reconciliation, and Restorative Justice: Introduction to a Special Issue of Social Justice Research

Social Justice Research -     

The Ethics of Respect in Negotiation

Negotiation Journal -     

The Special Case of Pesticides: Science and Regulation

Pesticide regulation is a data-intensive activity that is strongly controlled at the federal level. The pesticide law FIFRA controls pesticide sale, use, and disposal. Normal use of pesticides is excluded under RCRA and CERCLA. There are approximately 1,000 pesticide active ingredients with highly diverse functions ranging from insecticides to disinfectants and pheromones (insect sex attractants). There is a relatively large database on many pesticides, which helps reduce uncertainty in risk assessments. Witnesses subject to Daubert should be familiar with the data as well as the computer models designed for pesticides. “Inert” ingredients that are formulated with the pesticide active ingredients can become issues in torts cases. Federal courts have ruled both in favor and against FIFRA preemption, i.e., the ability of a plaintiff to seek relief in a torts case may be blocked by FIFRA. Golf course permitting provides a special land use whereby fundamental pesticide risk and regulatory issues are debated at the level of local planning and zoning commissions.