On identification problems requiring linked autosomal markers

This paper considers identification problems based on DNA marker data. The topics we discuss are general, but we will exemplify them in a simple context. There is DNA available from two persons. There is uncertainty about the relationship between the two individuals and a number of hypotheses describing the possible relationship is available. The task is to determine the most likely pedigree. This problem is fairly standard. However, there are some problems that cannot be solved using DNA from independently segregating loci. For example, the likelihoods for (i) grandparent–grandchild, (ii) uncle–niece and (iii) half-sibs coincide for such DNA data and so these relations cannot be distinguished on the basis of markers normally used for forensic identification problems: the likelihood ratio comparing any pair of hypotheses will be unity.Sometimes, but not in the examples we consider, other sources of DNA like mtDNA or sex chromosomes can help to distinguish between such equally likely possibilities. Prior information can likewise be of use. For instance, age information can exclude alternative (i) above and also indicate that alternative (iii) is apriori more likely than alternative (ii).More generally, the above problems can be solved using linked autosomal markers. To study the problem in detail and understand how linkage works in this regard, we derive an explicit formula for a pair of linked markers. The formula extends to independent pairs of linked markers. While this approach adds to the understanding of the problem, more markers are required to obtain satisfactory results and then the Lander–Green algorithm is needed. Simulation experiments are presented based on a range of scenarios and we conclude that useful results can be obtained using available freeware (MERLIN and R).The main message of this paper is that linked autosomal markers deserve greater attention in forensic genetics and that the required laboratory and statistical analyses can be performed based on existing technology and freeware.     

Gender differences in police officers' attitudes: Assessing current empirical evidence

Research on attitudinal differences between female and male police officers has burgeoned since the 1980s, producing a rich albeit at times contradictory legacy. Focusing on quantitative studies published after 1990, this current study reviewed empirical results regarding attitudinal differences between female and male police officers. A comprehensive search of the literature yielded thirty-three articles where gender was used either as an independent or control variable in multivariate regression analysis. A general finding was that officer gender has only a weak effect on officers' attitudes toward community policing, the community and neighborhood residents, job satisfaction, and domestic violence. There was some limited evidence showing that male and female officers differ in their attitudes toward the police role and stress. The limitations of this research are pointed out, and the directions for future research are identified.     

A review of the historical use and criticisms of gait analysis evidence

The use of gait analysis is a well-established facet of practice for many professions and a fundamental aspect of clinical practice. In recent times, gait analysis evidence has emerged as a new area of forensic practice. As its use has continued to spread and develop, the area of work has come under close scrutiny and subsequent criticism. The purpose of this paper is to examine the historical use of gait analysis evidence and consider the criticisms of this work. Through the use of the historical records of cases within the public domain it has been determined that gait analysis as evidence was first presented in court over 175?years ago, although it has only been utilized by experts in more recent times. The quality of analysis underpinning such evidence has been variable, and has been undertaken by both non-expert and expert witnesses. The work undertaken by expert witnesses appears to have been both non-scientific and scientific in nature, though there is limited reporting of cases involving scientific approaches. Given the variation in the quality of the methodologies utilized, there is the potential for confusion within the courts, where it may be difficult for the judge or jury to determine the appropriate weight that can be attributed to the evidence. It is concluded that future publications should explore the scientific basis of forensic gait analysis to evaluate standards, reliability and validity, as well as reporting the methodologies utilized in relevant cases in the field. It is also recommended that courts consider in greater depth an expert's theoretical approach and experience prior to admitting their evidence. The publication of ‘Forensic gait analysis: a primer for courts’, although limited in some aspects of its consideration of practice, is a welcome addition to the information available for guidance.     

The Uncovered Set and the Limits of Legislative Action

Ivan Jeliazkov Department of Economics, University of California, Irvine,Irvine, CA Itai Sened Department of Political Science, Washington University in St. Louis, St. Louis, MO We present a simulation technique for sorting out the size,shape, and location of the uncovered set to estimate the setof enactable outcomes in "real-world" social choice situations,such as the contemporary Congress. The uncovered set is a well-knownbut underexploited solution concept in the literature on spatialvoting games and collective choice mechanisms. We explain thissolution concept in nontechnical terms, submit some theoreticalobservations to improve our theoretical grasp of it, and providea simulation technique that makes it possible to estimate thisset and thus enable a series of tests of its empirical relevance.     

Risk of suicide ideation associated with problem-solving ability and attitudes toward suicidal behavior in university students

The present paper investigates the risk of lifetime suicide ideation associated with problem-solving ability and attitudes toward suicidal behavior in a sample of 328 university students (41% male, 59% female). The response rate was 77% based on the total number of students registered for the relevant courses. A series of questions assessed lifetime suicide ideation, while problem solving and attitudes toward suicide were measured using the Self-Rating Problem Solving scale and four subscales of the Suicide Opinion Questionnaire, respectively (McLeavey, 1986; Domino et al., 1989). Almost one-third of the students surveyed had lifetime suicide ideation. Both genders were similar in terms of their suicide ideation history, problem solving, and attitudes toward suicidal behavior with the exception that male students were more in agreement with the attitude that suicidal behavior lacks real intent. Compared with 2% of nonideators and ideators, one in four planners reported that they would more than likely attempt suicide at some point in their life. Greater agreement with the attitude that suicidal behavior is normal was associated with significantly increased risk of being an ideator, as was poor problem solving and less agreement with the attitude that suicidal behavior is associated with mental illness.     

The hand that rocks the cradle

This essay responds to Donald Hope's proposal that a woman's right to reproductive choice under the U.S. Constitution should end after she has been pregnant for eight weeks, because before that point science shows the developing embryo lacks human form, while after that point the fetus possesses physical characteristics that make it uniquely human. Hope's line purporting to determine when the fate of developing life becomes a matter of public concern rather than a strictly private decision is drawn both too early and too late. Eight weeks is too early because it imposes coerced motherhood on those least able to bear it while impugning the moral integrity of all women, and it is too late because this rule measures the value of human life by the utility of our physical features. Instead, no line need be drawn at all; the state can give effect to its concern for developing human life by valuing and supporting mothers who make it possible.