Postmortem changes in the level of calcium pumping adenosine triphosphatase in rat heart sarcoplasmic reticulum

The activity of calcium pumping adenosine triphosphatase (Ca2+-ATPase) in cardiac sarcoplasmic reticulum plays a pivotal role in myocardiac contraction-relaxation. The Ca2+-ATPase activity is controlled by phosphorylation and dephosphorylation of a sarcoplasmic reticulum protein "phospholamban" in response to neurotransmitters and drugs. To clarify the role of Ca2+-ATPase in the development of cardiac rigor mortis, we examined the changes of cardiac rigidity and cardiac sarcoplasmic reticulum Ca2+-ATPase activity up to 5 h after the decapitation of rats. Fifteen minutes after decapitation, the rats showed a cardiac rigidity on left ventricles. After 30 min, rigidity was obvious over the whole heart. After 1 h, the rigidity reached a high degree which was maintained for the rest of the observation period. On the other hand, the Ca2+-ATPase activity controlled by phosphorylation and dephosphorylation of phospholamban did not change for the whole observation period (5 h). Another Ca2+-ATPase activity representing the total amount of Ca2+-ATPase in sarcoplasmic reticulum gradually decreased. The data suggest that no significant phosphorylation or dephosphorylation of phospholamban occurs for a short time, at least for 5 h, after death and that the Ca2+-ATPase tends to relax the myocardium against the development of cardiac rigor mortis.     

Adolescents’ Engagement in Ethnic Harassment: Prejudiced Beliefs in Social Networks and Classroom Ethnic Diversity

Research on ethnic victimization to date has done little to identify the reasons why adolescents victimize their peers due to their ethnic background. To address this limitation, we examined: (1) the extent to which prejudiced attitudes within adolescents’ close and larger social networks determine their engagement in ethnic harassment, and (2) the extent to which classroom ethnic diversity plays a role in any such link. Our sample included 902 Swedish adolescents (M _age ?=?14.40, SD?=?.95; 50.3% girls). We found that Swedish adolescents who held negative attitudes toward immigrants or who were surrounded by prejudiced peers were more likely to be involved in ethnic harassment, particularly in classrooms with high ethnic diversity. Adolescents in classrooms with a high anti-immigrant climate were more likely to harass their immigrant peers. These findings suggest that prejudiced beliefs in youth social networks put young people at risk of engaging in ethnic harassment, particularly in ethnically diverse classrooms.     

The Development of Future Orientation is Associated with Faster Decline in Hopelessness during Adolescence

Hopelessness is implicated in multiple psychological disorders. Little is known, however, about the trajectory of hopelessness during adolescence or how emergent future orientation may influence its trajectory. Parallel process latent growth curve modelling tested whether (i) trajectories of future orientation and hopelessness and (ii) within-individual change in future orientation and hopelessness were related. The study was comprised of 472 adolescents [52% female, 47% Caucasian, 47% received free lunch] recruited at ages 12–13 who completed measures of future orientation and hopelessness at five annual assessments. The results indicate that a general decline in hopelessness across adolescence occurs quicker for those experiencing faster development of future orientation, when controlling for age, sex, low socio-economic status in addition to stressful life events in childhood and adolescence. Stressful childhood life events were associated with worse future orientation at baseline and negative life events experienced during adolescence were associated with both an increase in the trajectory of hopelessness as well as a decrease in the trajectory of future orientation. This study provides compelling evidence that the development of future orientation during adolescence is associated with a faster decline in hopelessness.     

Intergovernmental Agreements in Contemporary Russia

ABSTRACT

The paper discusses the evolution and current forms of agreements between federal, regional and municipal governments, as well as between the constituent units of the Russian Federation and municipalities. It analyses the problems and prospects of using these regulatory instruments. The purposes of this paper are to examine the current context of making intergovernmental agreements in Russia, to provide a comprehensive vision of contemporary state of this instrument of shaping intergovernmental relations, and to assess the prospects for their further practical use in the Russian Federation.     

Cognitive Vulnerabilities to Depression for Adolescents in Single-Mother and Two-Parent Families

Although research consistently suggests that adolescents in single-mother families are at increased risk for depression, the mechanisms that explain this relationship are unclear. In a community sample of adolescents (N?=?368; ages 12–16; 50?% female; 50?% White) and their mothers (42?% single), adolescents completed measures of depressive symptoms, rumination, and depressogenic inferential style at baseline and two yearly follow-ups. Mothers reported on stressful events that occurred in the child’s life from birth until baseline. Adolescents raised by single mothers, relative to partnered mothers, experienced more childhood stressors and higher rumination levels at 1-year follow-up. Additionally, higher rumination mediated the relationship between single motherhood and greater youth depressive symptoms at the 2-year follow-up. Clinical implications and developmental considerations are discussed.     

Organizational Citizenship Levels of Physicians in Public Hospitals

The aim of this study is to define organizational citizenship levels of physicians working in public hospitals. The population of the study consists of the physicians employed in the hospitals run by the Ministry of Health in Istanbul. The Organizational Citizenship Level Scale was used for the collection of data. It was found that the participants’ organizational citizenship levels were the highest in the “conscience” subsection and the lowest in the “praising the organization” subsection. Findings of this study provide clear information for the decision-makers and hospital managers in developing working conditions of physicians in public hospitals.     

Government and Corruption: Scylla and Charybdis

Using public sector employment and corruption perception data for 72 countries across the world, this article demonstrates that despite common notion countries with “smaller” governments do not tend to have lower corruption. Under general assumptions, one can demonstrate that there is an optimal size of public sector employment corresponding to the highest capital intensity. The model has several implications: lower optimal sizes of governments for labor intensive countries and higher sizes for capital intensive ones, possibility to reduce corruption paying a cost of suboptimal output, and a higher “price” of an oversized government for labor intensive countries.     

“一带一路”背景下两岸能源合作的政策选择

"一带一路"战略的提出为深化两岸合作提供了契机。依照"一带一路"战略的要求,结合两岸在能源领域的共同利益诉求,积极在能源领域展开合作,不仅保障两岸能源安全,还将为两岸实现宽领域、深层次的合作奠定基础。本文从两岸能源发展现状的对比出发,讨论了能源合作所能解决的地缘区域问题,分析了两岸加强资源勘探开发、技术合作研发、贸易市场拓展等具体合作路径的收益。融入21世纪海上丝绸之路,台湾与大陆将可进一步扩大合作,形成利益共同体,一起分享全球的商机。     

Lifestyles/Routine Activities and Bullying among South Korean Youths

Research on bullying has been conducted primarily in the United States and other western cultures, with less attention paid to the magnitude and sources of the problem in eastern cultures. Framed within lifestyle/routine activities theories, we examined a random sample of 3,121 South Korean middle-school students in order to assess the main effects of factors reflecting guardianship, target suitability, and exposure to motivated offenders on a youth’s risk of being bullied by groups of juveniles. Latent growth curve modeling was used to estimate both cross-sectional and longitudinal effects on self-reported victimizations involving “collective” bullying. Findings and their theoretical implications are presented.     

东盟争端解决机制的兴起、演进与启示

东盟争端解决机制自1996年正式形成以来,已历经1996年的《争端解决机制议定书》、2004年的《东盟促进争端解决机制议定书》和2010年的《东盟宪章争端解决机制议定书》三次变化。东盟争端解决机制的成因在于东盟区域一体化目标的推动以及“东盟方式”固有的制度缺陷。东盟争端解决机制的演进动因在于1996年的《争端解决机制议定书》缺乏操作性以及“规则导向”型争端解决机制在全球范围的兴起。东盟争端解决机制的三次变革可在争端解决机制的价值走向、模式选择及修正时机上给中国构建区域经贸争端解决机制提供一定的启示与借鉴。