Valence Politics and Equilibrium in Spatial Election Models

Spatial models of two-party or two-candidatecompetition almost never have pure-strategy Nashequilibria when the issue space has more than onedimension. This paper shows that the introduction ofvalence issues can create conditions where equilibriaexist, even in a multidimensional setting. We derivesufficient conditions for the existence of equilibria,and characterize the spatial locations of twocompeting parties or candidates when such equilibriaexist. The party with the advantage on the valencedimension will generally take a moderate position onthe positional issues. We consider the implications ofthese results for public perceptions of the parties,incumbency advantages, and realigning elections.     

Real-time forensic DNA analysis at a crime scene using a portable microchip analyzer

An integrated lab-on-a-chip system has been developed and successfully utilized for real-time forensic short tandem repeat (STR) analysis. The microdevice comprises a 160-nL polymerase chain reaction reactor with an on-chip heater and a temperature sensor for thermal cycling, microvalves for fluidic manipulation, a co-injector for sizing standard injection, and a 7-cm-long separation channel for capillary electrophoretic analysis. A 9-plex autosomal STR typing system consisting of amelogenin and eight combined DNA index system (CODIS) core STR loci has been constructed and optimized for this real-time human identification study. Reproducible STR profiles of control DNA samples are obtained in 2 h and 30 min with ≤0.8 bp allele typing accuracy. The minimal amount of DNA required for a complete DNA profile is 100 copies. To critically evaluate the capabilities of our portable microsystem as well as its compatibility with crime scene investigation processes, real-time STR analyses were carried out at a mock crime scene prepared by the Palm Beach County Sheriff's Office (PBSO). Blood stain sample collection, DNA extraction, and STR analyses on the portable microsystem were conducted in the field, and a successful “mock” CODIS hit was generated on the suspect's sample within 6 h. This demonstration of on-site STR analysis establishes the feasibility of real-time DNA typing to identify the contributor of probative biological evidence at a crime scene and for real-time human identification.     

Counting the costs of HIV and AIDS to civil-society organisations

HIV threatens the survival of many civil-society organisations (CSOs) in Africa. While we know the range of potential costs to such groups, we lack a detailed picture of the extent of the impact. This article highlights important findings from exploratory research in Malawi. Respondents perceived that overall performance in the four CSOs studied declined by an average 20 per cent because they were working in a context of high HIV prevalence. Yet the CSOs' workplace response to this threat was very limited, and they remain highly vulnerable to future impact. We consider why the CSOs have not been more proactive, and we recommend that donor policy should help partners to respond to the epidemic and enable them to remain effective.     

House organ

“A vast, depopulated coutry; a low density of automobiles, which are propelled by a type of gas with little sulphur; windy cities with no thermal inversions; a fairly recent genocide of dissident intellectuals and political activists; an even more recent economic collapse; a fragmented and quarrelsome left; a current government economic policy which assures stability at the price of decreased wagest less job security and increased unemployment — all these ingredients serve to suggest that red-green politics are not exactly booming in Argentina.“