全文获取类型
收费全文 | 296篇 |
免费 | 8篇 |
专业分类
各国政治 | 15篇 |
工人农民 | 12篇 |
世界政治 | 19篇 |
外交国际关系 | 14篇 |
法律 | 185篇 |
政治理论 | 58篇 |
综合类 | 1篇 |
出版年
2023年 | 2篇 |
2022年 | 3篇 |
2021年 | 1篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 11篇 |
2017年 | 16篇 |
2016年 | 12篇 |
2015年 | 13篇 |
2014年 | 13篇 |
2013年 | 37篇 |
2012年 | 14篇 |
2011年 | 10篇 |
2010年 | 16篇 |
2009年 | 18篇 |
2008年 | 17篇 |
2007年 | 12篇 |
2006年 | 11篇 |
2005年 | 7篇 |
2004年 | 9篇 |
2003年 | 6篇 |
2002年 | 7篇 |
2001年 | 8篇 |
2000年 | 11篇 |
1999年 | 3篇 |
1998年 | 2篇 |
1997年 | 1篇 |
1996年 | 2篇 |
1995年 | 1篇 |
1994年 | 2篇 |
1993年 | 3篇 |
1992年 | 1篇 |
1991年 | 1篇 |
1990年 | 4篇 |
1989年 | 3篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 3篇 |
1984年 | 1篇 |
1981年 | 1篇 |
1980年 | 2篇 |
1979年 | 3篇 |
1977年 | 1篇 |
1974年 | 2篇 |
1973年 | 1篇 |
1970年 | 2篇 |
1963年 | 1篇 |
排序方式: 共有304条查询结果,搜索用时 15 毫秒
71.
72.
73.
Klaus von Lampe 《Trends in Organized Crime》2016,19(1):106-109
74.
75.
Advances in pharmacogenomic research and increasing industry interest in personalized medicine have important implications for the way that orphan drug policies are interpreted and applied. Concerns have been raised about the potential impact of pharmacogenomics and new genomic technologies on our understanding of how disease categories are delineated, and subsequently, how the concept of rare disease should be defined for the purposes of orphan drug policies. This article considers whether orphan drug legislation can be drafted in a way that will maximize benefits and minimize concerns relating to the impact of pharmacogenomics on orphan drug research and development. After reviewing the issues that may arise at the intersection of orphan drug policies and pharmacogenomics, this article will discuss the potential impact of pharmacogenomics at two critical points: orphan designation and approval of the drug product. At each of these points, the relevant aspects of current US orphan drug legislation are examined, focusing on the extent to which recent amendments may address concerns that have been raised previously. This analysis will then provide the foundation for a critical review and recommendations regarding the proposed new Canadian orphan drug framework. 相似文献
76.
Klaus von Lampe 《Trends in Organized Crime》2013,16(2):258-263
77.
Chu M Gerostamoulos D Beyer J Rodda L Boorman M Drummer OH 《Forensic science international》2012,215(1-3):28-31
Oral fluid (OF) has become a popular specimen to test for presence of drugs, particularly in regards to road safety. In Victoria, OF specimens from drivers have been used to test for the presence of methylamphetamine (MA) and Δ(9)-tetrahydrocannabinol (THC) since 2003 and 3,4-methylenedioxy-N-methylamphetamine (MDMA) since 2006. LC-MS/MS has been used to test the most recent 853 submitted OF specimens from Victoria Police for 31 drugs of abuse including those listed in the Australian Standard AS4760-2006. At least one proscribed drug was detected in 96% of drivers, of which MA was the most common (77%), followed by THC (42%), MDMA (17%) and the combination of all three (3.9%). Opioids were detected in 14% of drivers of which 4.8% were positive for 6-acetylmorphine and 3.3% for methadone. The incidence of the opioids tramadol (1.2%) and oxycodone (1.1%) were relatively low. Cocaine (8.0%) was as commonly detected as benzodiazepines (8.0%), and was almost always found in combination with MA (7.9%). Samples positive to benzodiazepines were largely due to diazepam (3.5%) and alprazolam (3.4%), with only 0.2% of drivers combining the two. Ketamine was also detected in 1.5% of cases. While the incidences of the proscribed drugs itself are concerning, it is clear that many drivers are also using other drugs capable of causing impairment. 相似文献
78.
Drummer OH Kourtis I Beyer J Tayler P Boorman M Gerostamoulos D 《Forensic science international》2012,215(1-3):14-17
In mid 2009 Victoria introduced compulsory drug testing of blood taken from all injured drivers taken to hospital. Δ(9)-Tetrahydrocannabinol (THC), methylamphetamine (MA) and 3,4-methylenedioxy-methylamphetamine (MDMA) are prohibited and if drivers are positive to any amount an automatic penalty is enforced. Laboratory screens were conducted on preserved blood using ELISA testing for cannabis metabolite and methylamphetamines and a fully validated LC-MS/MS method for 105 drugs including THC, amphetamines, opioids, benzodiazepines, antidepressants and antipsychotics and a number of other psychoactive substances using a minimum of two transitions per drug. Conventional GC-testing for ethanol was used to screen and quantify the presence of alcohol. 1714 drivers were tested and showed alcohol in 29% (≥ 0.01 g/100mL) and drugs in 35%. The positive rate for the three drugs prohibited by legislation was 12.5%. The prevalence of THC, MA and MDMA was 9.8%, 3.1%, and 0.8%, respectively. The range of THC concentrations in blood was 2-42 ng/mL (median 7) of which 70% had a concentration of 10 ng/mL or higher. The range of concentrations for MA and MDMA was 0.02-0.4 and 0.03-0.3mg/L (median for both drugs was 0.05 mg/L). Drugs of any type were detected in 35% of cases. The other drugs were largely prescribed drugs such as the antidepressants (9.3%) and benzodiazepines (8.9%). Neither 6-acetylmorphine nor cocaine (or benzoylecgonine) was detected in these cases. 相似文献
79.
Patrick von Maravic 《Policy Sciences》2012,45(2):153-168
How can scientists acquire an adequate level of knowledge on phenomena whose actors actively conceal their activities? Social phenomena such as terrorism, sects, corruption, Mafia organizations, drug dealers, or government intelligence agencies actively guard their secrecy, conceal their activities, decide who is allowed (not) to know, and have no interest in being observed or understood by others. The article discusses the consequences of researching difficult-access problems for doing multi-method research. In an ideal?Ctypical approach, we distinguish between social problems that can be easily accessed and those that are difficult to access or non-accessible. To distinguish the two, we define characteristics that eventually lead to the conclusion that scientific inquiry that follows the conventional paradigm of professionalism, transparency, and replicable research reaches its limits when confronted with the active resistance of phenomena that do not like to be observed, understood, or critically approached. From this flows, the necessity to think about interdisciplinary, collaborative, and investigative modes of research that come with various prices. 相似文献
80.
Klaus von Lampe 《Trends in Organized Crime》2013,16(4):438-440