Immundefiziente Labortiere im System des Tierschutzrechts

Natur und Recht - Zucht und Haltung immundefizienter Labortiere wurden bislang nicht als Tierversuch gewertet, soweit die Tiere mit an Sicherheit grenzender Wahrscheinlichkeit nicht aufgrund des...     

Economic Elites and Support for Housing Affordability Policy: How a Housing-Health Belief Matters

Political Behavior - To investigate economic elites’ housing policy preferences and test the attitudinal, contextual, political, and economic conditions that drive support for affordable...     

Non-compliance by design: Moribund hard law in international institutions

States often create international institutions that impose legally binding rules on member states, and then do not even attempt to enforce these rules. Why? In this article, we present a game-theoretic model of moribund hard law in international institutions. We show that if some states face domestic pressure to negotiate a hard law treaty, their incentive to insist on hard law in the negotiations is maximized when less enthusiastic states expect that the hard law will probably not be enforced. Domestic proponents of hard law reward states for negotiating a hard law treaty, while states that oppose hard law can accept it because they expect no enforcement. As a form of informal governance, moribund hard law allows non-compliance by design.     

Time-resolved hair analysis of MDMA enantiomers by GC/MS-NCI

The aim of the study was to determine the enantioselective disposition of 3,4-methylenedioxymethamphetamine (MDMA) and other amphetamine-type stimulants (ATS) in segmented hair specimens of self-declared ecstasy abusers, who took part in a double-blind placebo-controlled six-way crossover study during approximately 7 weeks, during which they received a 75 and a 100 mg dose of racemic MDMA twice. Hair specimens were washed and cut into pieces of 2 cm length. After digestion and solid phase extraction, the enantiomers were derivatized with a chiral agent (2S,4R)-N-heptafluorobutyryl-4-heptafluorobutoyloxy-prolyl chloride, developed at the authors laboratory and quantified by gas chromatography coupled to mass spectrometry operating in the negative chemical ionization mode. Most of the hair specimens that were tested positive for MDMA showed a predominance of the (R)-enantiomer. The R/S ratios of MDMA varied between 1.02 and 2.75 and total concentrations ranged from 0.1 to 20.1 ng/mg. The enantiomers of its metabolite 3,4-methylenedioxyamphetamine (MDA) were also quantified in most hair segments. The R/S ratios of MDA varied between 0.60 and 1.60, while the concentrations of the enantiomers ranged from 10 to 160 pg/mg hair. When segmental analysis was performed on single hair specimens, no inversion of the R versus S ratios of MDMA and MDA was observed. The predominance of (R)-MDMA in hair was in accordance with those already published for other matrices. Furthermore, both enantiomers of amphetamine (AM) were also detected in hair segments of four volunteers and the R/S ratios ranged from 1.00 to 1.47.     

Organised crime threat assessments: a critical review

Since the beginning of the 21st century, several national and international government agencies have initiated organised crime threat assessments. Additionally, a few scholars have published methods to assess the risks and threats of organised crime. These governmental bodies and scholars claim that their reports and methods can demonstrate that certain forms of organised crime are more threatening than others and thus help policy-makers set strategic priorities. In this article I discuss these claims by examining the reliability and validity of the operational definitions of the key concepts used, such as organised crime, threat and risk. This examination reveals that most reports and methods provide insufficient detail—and sometimes even no details at all—to guarantee the reliability and validity of their operational definitions. The search for validity is made particularly difficult by the ambiguity surrounding the concepts of organised crime, threat and risk, while the concept of cost is less problematic. Moreover, establishing what constitutes a threat is at its core a normative decision that cannot be left to intelligence analysts or scientists alone. The challenge ahead lies in acknowledging the normative framework of organised crime threat assessments and within that framework maximising the reliability and validity of the operational definitions of key concepts and related measuring instruments.     

Wachsende Lohnungleichheit in Deutschland

Based on the thesis of growing overall inequality in the German society, this paper discusses changes in the inequality of wages for the period between 1998 and 2006. Our objective is to identify differences in real wage growth for various occupational classes. The theoretical foundation of the article is based on economic as well as sociological concepts. With regard to recent findings of labor economists, one could postulate that market forces driven by technological changes and the corresponding growth in the relative demand for highly-skilled labor have led to an increase in wage inequality (skill-biased technological change, SBTC). In contrast, a structural theory approach, based on the work of Aage B. Sørensen, would argue that increasing wage inequality is due to changes in the extent to which certain labor market groups are able to generate rents. For the empirical analysis, data from the German Socio-Economic Panel (GSOEP) and data from the BIBB/IAB-Survey are used. Our results show that people in lower occupational classes belong to the losers of the general income dynamics in Germany between 1998 and 2006. Moreover, the inclusion of a broad variety of characteristics of the occupational position reveals that the growth of wage inequality in Germany can be explained by skill-biased technological changes, but also by changes in rent generating processes.     

Eisenhower, the British and the security of Hong Kong, 1953-60

This article is an examination of Hong Kong's importance within British-American security arrangements in the Far East during the presidency of Dwight D. Eisenhower. Archival evidence indicates that the Eisenhower Administration accepted a greater deal of commitment to the defence of Hong Kong during the 1950s — a period of significant hostility between the United States and the People's Republic of China. To understand this policy evolution in the broader context, this study evaluates the differences in British and American attitudes towards China during the 1950s and the effect of this on US policy towards Hong Kong.     

Deliberate self-harm and suicide attempt in custody: distinguishing features in male inmates' self-injurious behavior

Self-injurious behavior involving deliberate self-harm and suicide attempts by inmates while under custodial authority is a major problem for prisons and jails (prevalence, legal obligation for suicide prevention, and stress for officers). The differentiation of "serious" vs. "non-serious" and often manipulative suicide attempts as distinct phenomena, each with its own clinical features, is controversially discussed in current literature and a challenge for every diagnostician. If distinct clinical presentations and histories can be observed, an estimation of the seriousness of each act of self-injurious behavior can be simplified, whereby appropriate treatment of the individual case becomes possible. The aim of the study was to find differences between self-injurious behavior of "low seriousness" (i.e. low lethality and low suicidal intent) and of "high seriousness". Therefore, inmates showing self-injurious behavior were divided into subgroups of deliberate self-harm and suicide attempters on the basis of the act's intent and lethality. This was followed by a comparison of the clinical presentations of the individual inmates constituting the subgroups. Hence, 49 inmates showing self-injurious behavior were interviewed and tested with a variety of instruments (SCID-I and II, PCL-R, BDI-II, BHS, BSS, SIS, etc.), and their prison and health files were examined. The results indicate significant correlations between seriousness and some demographic, prison-related variables as well as different measures of depression. Negative, but nonsignificant correlations could be observed with regard to cluster B personality disorders. The PCL-R total score as well as PCL-R factor 1 showed a statistical trend for negative correlations with measures of seriousness. Inmates showing deliberate self-harm and suicide attempters seem to differ in a number of ways. Implications on how the individual prisoner should be treated are discussed.     

Hydrogen: Fueling EU-Morocco Energy Cooperation?

The war in Ukraine and the looming threat of climate change are driving the strategic need to diversify sources of energy, including renewables. Therefore, the European Union aims to develop energy relations with non-EU member states, and Morocco has become a key priority. Both Brussels and Rabat are pursuing ambitious green policies and cooperation initiatives, including on hydrogen. Drawing on theories of international institutions and political economy, this article analyzes hydrogen-related relationship patterns and explains demand and supply factors as drivers of institutionalized energy cooperation. We examine the EU's hydrogen approach and development, its relations with Morocco, and the political interests of both sides. Our analysis shows that the complex interdependencies in the evolving EU-Morocco hydrogen relations indicate that demand can be met by supply. However, challenges remain, including the need to deepen the partnership and prepare the market for commercial hydrogen production.