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61.
Evaluating the discriminating power of amino acid ratios on distinguishing dark colored hair samples
Timothy Yaroshuk MS Robert H. Powers PhD Alyssa L. M. Marsico PhD 《Journal of forensic sciences》2023,68(2):416-424
Human hairs are one of the most commonly encountered items of trace evidence. Currently, conventional methods for hair analysis include microscopic comparison and DNA analysis (nuclear and mitochondrial). Each approach has its own drawbacks. Hair proteins are stable and offer an alternative to DNA testing, as demonstrated with proteomics for distinguishing humans. However, proteomics is complicated and requires identifying peptides to remain intact following harsh sample preparation methods. Alternatively, the actual amino acid content of a hair sample may also offer important identifying information and actually requires proteins and peptides to be broken down completely rather than remaining intact. This study evaluated the discriminating power of using hair amino acid ratios to differentiate hair samples from 10 unrelated individuals with dark colored hair. Hair proteins were digested, derivatized, and analyzed using gas chromatography–mass spectrometry. Amino acid ratios were calculated for each individual and comparisons using ANOVA and post-hoc pairwise t-test with Bonferroni correction were made with amino acid ratios for individuals. Overall, out of the 45 possible pairwise comparisons between all hair samples, 38 (84%) were differentiable. Out of the 36 possible pairwise comparisons between brown haired individuals, 32 (89%) were considered differentiable using univariate statistics. Multivariate statistics were also attempted but, overall, univariate models were sufficient for exclusionary purposes. These results indicate that amino acid ratio analysis can potentially be used as an exclusionary method using hair if DNA analysis cannot be performed, or to corroborate conclusions made following microscopic analysis. 相似文献
62.
Sandra E. Rodriguez-Cruz PhD 《Journal of forensic sciences》2023,68(5):1555-1569
Illicit fentanyl has flooded the United States' drug market, increasing the risk of overdose and poisonings throughout the general population and accidental exposure among law enforcement officers confiscating the increasing number of seizures. Fentanyl test strips (FTS) are used to obtain presumptive information about the presence of fentanyl in a suspected sample. However, their adoption by law enforcement personnel and seized-drug analysts has been limited because most products are advertised for urine testing, not for assays using water solutions. This study presents an evaluation of four commercial FTS: Rapid Response from BTNX, Inc.; T-Dip Fentanyl (FTY) Urine Dip Cards obtained from Amazon.com ; Premier BioDip FYL10 from Premier Biotech Inc.; and MobileDetect Fentanyl strips from DetectaChem, Inc. Performance characteristics curves were used to compare the products' sensitivity, showing that all can reliably detect fentanyl in aqueous solutions at concentrations below 1 μg/mL, with some of the tests able to reliably detect the drug at 200 ng/mL. A stability study demonstrates the performance of all four FTS brands was only slightly affected after 30 days of storage at two extreme environmental conditions. Fentanyl-related substances are also evaluated using the Rapid Response FTS, which showed high cross-reactivity with para-fluorofentanyl and acetylfentanyl, but lower with ortho-chlorofentanyl, carfentanil, and 4-ANPP. Users should be aware that FTS may give false-negative results even when potentially dangerous levels of carfentanil are present. When testing other common drugs, adulterants, and diluents frequently encountered in seized tablets, concentration-dependent results were obtained and multiple instances of false positives were recorded. 相似文献
63.
64.
Christopher R. Berry Barry C. Burden William G. Howell 《American journal of political science》2010,54(1):1-17
While many scholars have focused on the production of legislation, we explore life after enactment. Contrary to the prevailing view that federal programs are indissoluble, we show that programmatic restructurings and terminations are commonplace. In addition, we observe significant changes in programmatic appropriations. We suggest that a sitting congress is most likely to transform, kill, or cut programs inherited from an enacting congress when its partisan composition differs substantially. To test this claim, we examine the postenactment histories of every federal domestic program established between 1971 and 2003, using a new dataset that distinguishes program death from restructuring. Consistent with our predictions, we find that changes in the partisan composition of congresses have a strong influence on program durability and size. We thus dispel the notion that federal programs are everlasting while providing a plausible coalition-based account for their evolution. 相似文献
65.
2007年6月,美韩双方签署了《美韩自由贸易协定》。美韩之间为什么要签署该协定?该协定对两国国内分别产生了哪些影响?该协定为何至今没能获得美国国会的通过?针对上述问题,本文结合美国贸易政策理论,从体系、国家和社会三个层面对其进行了分析。《美韩自由贸易协定》的签署及其实施,在体系层面上将会为双方带来经济、政治和战略上的多重收益,而在社会层面上却产生了不同的反应。尽管由于国内经济困难和利益集团的掣制使得协定的通过还面临不小的阻力,但基于协定所蕴含的重要价值和两国政府对此认识的高度一致,协定获得通过只是时间上的问题。 相似文献
66.
东亚-北美经济失衡与再平衡分析 总被引:1,自引:0,他引:1
本文从国别结构和产品结构分析了20世纪90年代以来东亚—北美经济失衡的变化,认为美国贸易逆差不断扩大是其对外产业转移的结果,东亚地区贸易顺差与日俱增是其承接产业转移的结果。其中,东亚内部再次产业转移导致中国顺差迅速膨胀。为了实现东亚—北美经济再平衡,美国需要采取一些措施扩大出口,控制过度的信贷消费,并对美元采取更加负责的政策;东亚地区需要努力实现由外需驱动型向内需驱动型增长方式的转变,加快产业调整与升级,并把产业链向其他地区延伸。 相似文献
67.
绿色增长正在成为世界谋求经济社会可持续发展的重要经济模式,各国都在寻求实现绿色增长的发展战略。1997亚洲金融风暴、2008年以来的世界性经济衰退促使积极探索经济转型新路的韩国加快了战略转型的步伐。韩国政府为此提出并开始实施“低碳绿色增长战略”,制订并发表了“绿色增长国家战略与五年计划”以及相关的法规,详细阐述了韩国推进这一战略计划的长远规划、战略目标、实施计划、政策措施等,并建立了从中央到地方的组织实施机构。韩国积极推动的绿色增长战略充分揭示了其未来经济发展的基本方向,意在谋求实现经济增长方式的转变、构建未来经济长期稳定发展的新增长模式和动力。 相似文献
68.
Elizabeth M. Hammond Melissa A. Berry Dario N. Rodriguez 《Legal and Criminological Psychology》2011,16(2):242-252
Purpose. The purpose of this study was to examine the influence of rape myth acceptance, belief in a just world, and sexual attitudes on attributions of responsibility in a date rape scenario. We predicted that people higher in rape myth acceptance and those who more strongly believed in a just world, as well as those who held more conservative sexual attitudes, would attribute greater blame to the accuser than to the accused. Methods. One hundred seventy‐two undergraduates from a medium‐sized, Catholic university in the USA read a hypothetical date rape scenario and completed the Rape Myth Acceptance Scale, the Just World Scale, the Sexual Attitudes Scale, and a Judgment Questionnaire constructed for the current study. Results. Rape myth acceptance mediated the relationship between gender and judgments of responsibility for the accused and the accuser. Men were more likely to endorse rape myths and, consequently, assign less responsibility to the accused and more responsibility to the accuser than women. Conclusions. Pre‐existing beliefs regarding the nature of rape and the circumstances surrounding it may bias attributions of responsibility in date rape cases. There may be utility in addressing whether jurors hold such beliefs prior to the start of a trial. 相似文献
69.
70.
This article undertakes a detailed examination of the practical desirability and legal validity of arbitration clauses under the Nigerian legal regime. This involves navigating through provisions of the relevant Rent Control and Recovery of Premises Law. Areas of incompatibility (including those bordering on jurisdiction, penal provisions and enforcement of awards) between the latter law and arbitration clauses are then discussed. Finally, recommendations are made to the effect that the Rent Control and Recovery of Premises Law should be amended. 相似文献