Identification of ten corticosteroids in human hair by liquid chromatography-ionspray mass spectrometry

This paper describes a screening procedure based upon high-performance liquid chromatography-ionspray mass spectrometry for the identification of ten corticosteroids in human hair: triamcinolone, prednisolone, prednisone, methylprednisolone, cortisone, cortisol, beta- and dexamethasone, flumethasone and beclomethasone. Hair strands were washed in methylene chloride, pulverized in a ball mill and 50 mg of the powdered hair were incubated in 1 ml Soerensen buffer, pH 7.6 for 16 h at 40 degrees C, in presence of 50 ng cortisol-d3 used as internal standard. Purification of the incubation medium was achieved on SPE C18 Isolute extraction columns. The eluates were evaporated to dryness and resuspended in 30 microliters MeOH before analysis by HPLC-IS-MS in positive and negative modes of detection. The validation parameters were found satisfactory for a corticosteroid screening procedure. The correlation coefficient of the calibration curve ranged from 0.939 to 0.997, showing linearity between 0.1 and 10 ng/mg, excepted for beclomethasone which was between 0.2 and 10 ng/mg. Extraction recovery at 4 ng/mg ranged from 43.2 to 85.7%. Repeatability (CV values) at 4 ng/mg ranged from 6.1 to 17.5%. The limits of detection ranged from 0.03 to 0.17 ng/mg for a signal-to-noise ratio of 2. The detection of prednisone and beclomethasone in three hair specimens obtained from forensic and clinical cases have documented corticosteroids incorporation into human hair.     

‘Fanm Se Poto Mitan’: Haitian Woman,the Pillar of Society

In this paper Marie-Jose N'zengou-Tayo draws on a variety of sources, both historical and contemporary, to describe the journey of Haitian women from nineteenth-century post-War of Independence, to present-day Haitian society.The paper is divided in two sections. In the first, the author traces a brief social history of women, quoting anthropological and sociological studies from the 1930s to the 1970s. She begins with rural peasant women noting their significant involvement in farming, marketing and in the internal food trade sector. The development of polygamy and common law unions as the most common form of conjugal union is seen as a practical response to survival in rural Haiti. The author notes the major impact on women's lives of continued political upheavals, violent repression, rural degradation and migration to the cities. Opportunities for employment in a deprived urban setting, and women's initiatives in income generating are also described under the Duvalier regimes. A brief overview of the lives of the middle class is included, although there is a paucity of research in this area available to the author. Violence against women is a regular threat facing domestic workers, and a means of repression used by the state against women across classes.In the second section N'Zengou-Tayo addresses the literary representation of Haitian women by both female and male Haitian writers. The paper examines how female writers have developed subversive narrative strategies to shape a female identity in order to break away from the stereotypes portrayed in men's writing.N'Zengou-Tayo concludes that the tremendous contribution of Haitian women to their society has neither been recognized nor documented. Despite this, the resilience of Haitian women, whether in their daily lives or in their writing, has enabled them to make strides towards improving their lives.     

The electoral budget cycle

This article begins with a review of the now substantial literature on the thesis that polticians manipulate governmental outputs so as to favor their chances of reelection. It concludes that while this “electoral cycle” thesis was initially overstated by its proponents, it retains more plausibility than recent critics have allowed. This conclusion is then demonstrated through an analysis of expenditures by the ten provincial governments in Canada between 1951 and 1984.     

Assassination and the law: A policy memorandum

Normally, assassination is a crime under international law. Yet there are rare, residual circumstances where it may be not only permissible but law enforcing. Insofar as international law is part of United States law, assassination might—in these very extraordinary circumstances—not be unlawful. Drawing on the explicit expectations of international law and the natural law foundations of U.S. municipal law, this article acknowledges that assassination must always be impermissible as an instrument of Realpolitik, but that in a world that continues to confront innocent populations with terrible harms (terrorism, war, genocide) assassination does have a proper place. Throughout this examination, philosophical and jurisprudential perspectives are fused with both pertinent tactical considerations and utilitarian calculations.     

Globalisation,civil society,and the multilateral system

This paper analyses the significance and scope of globalisation, focusing on its implications for the autonomy of national actors, on the one hand, and on the new demands that global governance imposes upon multilateral action, on the other. It is argued that the current form of globalisation is in fact compatible with some degree of autonomous coordinated social action outside the realm of the market. This allows us both to differentiate between the realities and mystification (i.e. ideology) that underlie the concept of globalisation and to reject the standard discourse and economic therapy offered by certain international organisations to developing countries. If globalisation does not rule out the possibility of autonomous nationallevel action, it also establishes the basis for more solid and effective multilateral action. The factors that support the need for such action in the future are analysed; action that responds to demands for greater management of international public assets, and to calls for more effective global governance. The article ends by identifying the essential characteristics of such a multilateral system if it is to meet the needs arising from a new international reality.     

SEM/EDS analysis and characterization of gunshot residues from Brazilian lead-free ammunition

The exposition to heavy metal-rich airborne due to fire practicing has forced to the development of heavy metal-free environmental ammunition primers all over the world. Here we characterize the GSR elements present in the Brazilian lead-free ammunition produced by Companhia Brasileira de Cartuchos (CBC) and commercialized by MagTech in the U.S. and Europe under the name CleanRange centerfire cartridges. Both first and second generations of CleanRange in calibers 9 mm Luger, .40 S&W, .380 AUTO and .38 SPL were analyzed and compared to regular Brazilian CBC ammunition by scanning electron microscopy/energy dispersive spectroscopy. Differences in composition and morphology of GSR particles from the two generations of CleanRange were observed. The first generation ammunition (found in Europe) presented spherical particles, being strontium the only unique element detected. The second generation (found in the U.S.) produced irregular particles composed mostly by potassium, aluminum, silicon and calcium. We can conclude that identification of GSR derived from CBC second generation lead-free ammunition in suspects' hands may be impossible without the addition of a distinct metallic taggant in the primer composition by the manufacturer.     

Criminal Justice in a Democracy: Towards a Relational Conception of Criminal Law and Punishment

This article starts from the observation that in classical Athens the discovery of democracy as a normative model of politics has been from the beginning not only a political and a legal but at the same time a philosophical enterprise. Reflections on the concept of criminal law and on the meaning of punishment can greatly benefit from reflections on Athenian democracy as a germ for our contemporary debate on criminal justice in a democracy. Three main characteristics of the Athenian model will be analysed: the self-instituting capacity of a democracy based on participatory and reflective citizenship, political power as the capacity of citizens for co-operating and co-acting with others, and the crime of hubris as one of the key issues in Athenian criminal law. These analyses will lead to the conclusion that one of the key issues of a democratic legal order lies in its capacity of recognizing the fragility of the human condition and of developing workable and effective standards of justice in that context. A relational conception of criminal law and punishment, based on proportionality, reflexivity, mutual respect and responsibility fits best with a democracy under the rule of law.