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Managing incidental findings in human subjects research: analysis and recommendations. 总被引:8,自引:8,他引:0
Susan M Wolf Frances P Lawrenz Charles A Nelson Jeffrey P Kahn Mildred K Cho Ellen Wright Clayton Joel G Fletcher Michael K Georgieff Dale Hammerschmidt Kathy Hudson Judy Illes Vivek Kapur Moira A Keane Barbara A Koenig Bonnie S Leroy Elizabeth G McFarland Jordan Paradise Lisa S Parker Sharon F Terry Brian Van Ness Benjamin S Wilfond 《The Journal of law, medicine & ethics》2008,36(2):219-48, 211
No consensus yet exists on how to handle incidental findings (IFs) in human subjects research. Yet empirical studies document IFs in a wide range of research studies, where IFs are findings beyond the aims of the study that are of potential health or reproductive importance to the individual research participant. This paper reports recommendations of a two-year project group funded by NIH to study how to manage IFs in genetic and genomic research, as well as imaging research. We conclude that researchers have an obligation to address the possibility of discovering IFs in their protocol and communications with the IRB, and in their consent forms and communications with research participants. Researchers should establish a pathway for handling IFs and communicate that to the IRB and research participants. We recommend a pathway and categorize IFs into those that must be disclosed to research participants, those that may be disclosed, and those that should not be disclosed. 相似文献
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Hon. Joseph V. Kay 《Family Court Review》2010,48(3):401-402
Editor's note on the 5th World Congress on Family Law and Children's Rights held in Halifax Nova Scotia, August 23–26, 2009 相似文献
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Veysey Bonita M. Steadman Henry J. Morrissey Joseph P. Johnsen Matthew Beckstead Jason W. 《Law and human behavior》1998,22(2):205-215
The prevalence of serious mental illnesses in jail populations is significantly greater than in the general population. Identifying individuals who warrant psychiatric evaluations is important and benefits correctional staff as well as detainees. One widely used screening instrument intended for this task is the Referral Decision Scale (RDS). This paper reviews the development and validation of the RDS. Using data from a multisite study which assessed postrelease outcomes for detainees with mental illness, various types of validity are addressed. The results confirm that the RDS has some inherent characteristics that seriously limit its practical application as a screening instrument for use by correctional staff. 相似文献
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Suad Joseph 《Citizenship Studies》1999,3(3):295-318
The mechanisms which underpin kinship are mobilized by states to organize the citizenry for state‐building, often transporting patriarchy and (reinscribing it in public arenas. While the gendering and aging of citizenship is predictable in the deployment of patriarchal kin institutions for state‐building, the focus of this paper is less on these outcomes (well theorized elsewhere) and more on a mechanism undertheorized in feminist analyses of patriarchy and state dynamics—patrilineality. Patrilineality is commonly subsumed in feminist analyses of patriarchy, particularly in the study of the Middle East. Understood as kinship descent through the father's lineage, patrilineality is often conflated with patriarchy in societies in which both are present, resulting in the essentialization of patriarchy and a glossing of critical cultural differences in the gendering and aging of citizenship. While kinship in Lebanon has been fluid and Lebanese have mobilized both patrilineal and matrilineal principles of kinship as deemed necessary, the codification of rules of patrilineal descent in citizenship laws by the state has narrowed the spaces for negotiation for women and men, children and adults. By disaggregating patrilineality from patriarchy, this paper exposes a key substructure of patriarchy, significant to the gendering and aging of citizenship in Lebanon. 相似文献
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