Validation of new methods

Reliable analytical data are a prerequisite for correct interpretation of toxicological findings in the evaluation of scientific studies, as well as in daily routine work. Unreliable analytical data might not only be contested in court, but could also lead to unjustified legal consequences for the defendant or to wrong treatment of the patient. Therefore, new analytical methods to be used in forensic and/or clinical toxicology require careful method development and thorough validation of the final method. This is especially true in the context of quality management and accreditation, which have become matters of increasing relevance in analytical toxicology in recent years. In this paper, important considerations in analytical method validation will be discussed which may be used as guidance by scientists wishing to develop and validate analytical methods.     

Associations between expectancies of alcohol and drug use, severity of partner violence, and posttraumatic stress among women

Women who experience recurrent intimate partner violence (IPV) may use alcohol or drugs because they expect that these substances will help them cope with the negative physical and psychological sequelae of IPV. However, expectancies for alcohol and drug use have not been explored among this population of women. We used the Relaxation and Tension-Reduction Scale, Arousal and Aggression Scale, and Social Assertion Scale of the Alcohol Expectancy Questionnaire and modified its items to assess both alcohol and drug expectancies of 212 community-based, IPV-exposed women. Results of bivariate correlations showed that greater alcohol and drug expectancies were significantly correlated with greater alcohol problems and greater posttraumatic stress total and symptom severity scores. Results of a multivariate regression model showed that after controlling for demographic characteristics and history of childhood trauma, Relaxation and Tension- Reduction expectancies were associated with number of days of alcohol use, alcohol problems, physical and sexual IPV severity scores, and posttraumatic stress total and reexperiencing symptom severity scores. Expectancies do not significantly moderate the relationships between IPV, posttraumatic stress, and problematic alcohol and drug use. Given the strong relationships of expectancies with IPV severity, posttraumatic stress, and alcohol problems, expectancies may serve as targets for interventions to reduce alcohol use and problems and improve health-related outcomes in IPV-exposed women.     

“My World Is Upside Down”: Transnational Iraqi Youth and Parent Perspectives on Resettlement in the United States

The U.S. war with Iraq led to the displacement of millions of Iraqis, many of whom have resettled in the United States as refugees. We explore the challenges Iraqi families face after resettlement, with a particular focus on the agency of refugees and challenges/opportunities of familial social reproduction in a transnational context. We conducted 181 qualitative interviews with 38 Iraqis (11 youth, 27 adults) and 5 service providers. Our findings highlight the importance of exploring refugee agency and illuminate how the interplay between structure and agency in transnational contexts is a useful framework for understanding transformations around social roles.     

The policy process in developed and less developed political systems

The author argues that we do not really know how different the policymaking systems of developed and developing nations are. In his view, policymaking in less developed regimes is different from that which occurs in more affluent countries. However, the differences are frequently overstated. After analyzing several problems of the policymaking process, Peters concludes that the differences are larglely those of degree rather than of fundamentally different types of policy problems and processes. He concludes that what may matter is the degree of difficulty governments encounter in policymaking, and in some ways the less developed countries may actually enjoy some real advantages. At the same time, however, they have more informational, financial and ideological barriers that impose political limitations on policy learning.     

“YFlag” – A Single‐base Extension Primer Based Method for Gender Determination

Assigning the gender of a DNA contributor in forensic analysis is typically achieved using the amelogenin test. Occasionally, this test produces false‐positive results due to deletions occurring on the Y chromosome. Here, a four‐marker “YFlag” method is presented to infer gender using single‐base extension primers to flag the presence (or absence) of Y‐chromosome DNA within a sample to supplement forensic STR profiling. This method offers built‐in redundancy, with a single marker being sufficient to detect the presence of male DNA. In a study using 30 male and 30 female individuals, detection of male DNA was achieved with c. 0.03 ng of male DNA. All four markers were present in male/female mixture samples despite the presence of excessive female DNA. In summary, the YFlag system offers a method that is reproducible, specific, and sensitive, making it suitable for forensic use to detect male DNA.     

The Public–Private Distinction: Insights for Public Administration from the State Action Doctrine

Public administration scholars continue to grapple with how and why public organizations differ from private organizations. The judiciary deals with similar questions in ruling on constitutional claims that apply exclusively to state actors. The authors consider similarities and differences between scholarly and judicial approaches, adding to the body of research attempting to capture the complexities of the public–private distinction. The application in this article includes the coding of seminal court decisions and qualitative comparative analysis (QCA) to find combinations of causal conditions that lead to state action rulings. The specifics revealed through QCA provide valuable lessons for extending public norms and preserving constitutional protections when outsourcing public services.     

The Centralisation of Parliamentary Policy Statements in Western European Parliaments

Parliamentarians and their party groups can employ many different instruments to communicate policy statements to their electorate (debates in plenary, presentations of committee reports, oral questions, written questions, and interpellations). Therefore, the design of these instruments should be analysed in one common framework. This paper seeks to provide a first step towards this goal by mapping and explaining the centralisation of parliamentary policy statements in all western European countries with a parliamentary system. It is argued that, on a theoretical level, there are two different causes for a stronger or weaker centralisation of the instruments of parliamentary policy statements: the electoral connection and efficiency. Empirically, it is shown that there are striking differences in centralisation both within and between countries which are worth exploring further. Moreover, the results of the statistical models suggest that the electoral connection is the driving factor behind the centralisation of the instruments of parliamentary policy statements.     

Urgent issues and prospects at the intersection of culture,memory, and witness interviews: Exploring the challenges for research and practice

The pursuit of justice increasingly relies on productive interactions between witnesses and investigators from diverse cultural backgrounds during investigative interviews. To date, the role of cultural context has largely been ignored by researchers in the field of investigative interviewing, despite repeated requests from practitioners and policymakers for evidence-based guidance for the conduct of interviews with people from different cultures. Through examining cultural differences in human memory and communication and considering specific contextual challenges for investigative interviewing through the lens of culture, this review and associated commentaries highlight the scope for considering culture and human diversity in research on, and the practice of, investigative interviewing with victims, witnesses, and other sources. Across 11 commentaries, contributors highlight the importance of considering the role of culture in different investigative interviewing practices (e.g., rapport building, questioning techniques) and contexts (e.g., gender-based violence, asylum seeking, child abuse), address common areas of cultural mismatch between interviewer–interviewee expectations, and identify critical future routes for research. We call for an increased focus in the investigative interviewing literature on the nature and needs of our global community and encourage constructive and collaborative discussion between researchers and practitioners from around the world to better identify specific challenges and work together towards evidence-based solutions.