Genetic markers in human bone: I. Deoxyribonucleic acid (DNA) analysis.

Deoxyribonucleic acid (DNA) was isolated from a number of spongy and compact human bone tissue specimens, and the yield was estimated on a "per milligram of starting tissue" basis. DNA was, in addition, isolated from a number of corresponding blood and bone tissue specimens. Spectrophotofluorometry and ethidium bromide visualization on minigels were used to estimate the quantity and degree of degradation of DNA. The DNA from several blood-bone pairs is shown to give concordant restriction fragment length polymorphism (RFLP) typing results by two different typing protocols with five different single-locus probes. DNA from several additional blood-bone pairs is shown to give concordant results for human leucocyte antigen (HLA)-DQ alpha phenotypes following polymerase chain reaction (PCR) amplification and hybridization to specific allele-specific oligonucleotide (ASO) probes, and for the variable numbers of tandem repeats (VNTR) length polymorphisms 3' to the human apolipoprotein B (APOB) gene following PCR amplification with specific primers and analysis of the products by electrophoresis and ethidium bromide visualization.     

"Beaten to death". An autopsy series of homicidal blunt force injuries

Although gunshot is by far the most common means of homicide in the United States, significant numbers of homicides are also perpetrated by other means. Blunt-force injuries are produced by a variety of objects, including hands and feet and many different weapons. Some of these objects produce distinctive patterns of injury of potential evidentiary value. This paper presents a series of 20 consecutive blunt-force homicides in adults. Seventy percent (14 cases) of the victims were men. Thirty percent (six cases) followed an argument or altercation. A number of the weapons used were "weapons of opportunity" seized in the course of the incidents. Sixty-nine percent (nine cases) of known assailants were acquainted with their victims. Few characteristic patterned injuries were seen. Not surprisingly, craniocerebral trauma was the most common cause of death. One half (10 cases) the victims survived their assaults for varying periods of time. Homicides due to blunt-force injury still pose a significant challenge for the forensic pathologist, who must obtain a complete and accurate history of the fatal incident, interpret patterns of injury and other findings at autopsy, and correlate all of the findings to make an accurate ruling of the cause and manner of death.     

Contribution à une analyse narrative de la théorie institutionnelle

Conclusion Que faut-il penser de la co-existence de trois modèles différents pour interpréter l'élément central de la théorie institutionnelle de MacCormick? Cette pluralité de modèles n'est source de perturbations que pour ceux qui tiennent à défendre l'idée selon laquelle il n'y a qu'une seule forme possible de discours juridique. Dès qu'il est accepté — comme hypothèse de base — que les formes d'organisation de ce type de discours peuvent être multiples, la perspective est inversée.C'est le schéma explicatif — dit schéma narratif — qui est alors unique. Quant aux différentes variantes de la formule de MacCormick, elles représentent les altérations de cette définition en fonction de paramètres identifiables — et identifiés — comme le statut des différents actants et acteurs, la définition de l'objet de valeur final dont ils cherchent à s'emparer et les objets de valeur d'usage dont ils se servent.L'éclatement de la formule de Maccormick ne correspond alors plus à un rejet mais bien à une mise en question. Cette remise en question débouchant sur la reconnaissance de plusieurs schémas narratifs, nous devons nous demander dans quelle mesure notre perception de la phasep correspond à l'idée que s'en fait MacCormick. S'agit-il seulement de la procédure au sens juridique du mot ou de tout un ensemble d'actes permettant de persuader un destinateur comme un juge ou une administration de la coïncidence entre un parcours narratif effectif et le type idéal de parcours narratif qu'ils tirent de la lecture des normes juridiques?S'il s'agit bien de la procédure au sens juridique de ce mot, il faut alors préciser au terme de cette analyse sémio-narrative que l'ensemble des phénomènes pragmatiques — comme les interactions dans le cas d'une procédure orale — ne sont pris en compte ni par la formule de MacCormick, ni par la présente discussion mais qu'ils relèvent d'une recherche particulière sur cette dimension supplémentaire, certes compatible avec la théorie sémiotique mais pas avec la théorie institutionnelle de MacCormick. Pour conclure, nous dirons donc qu'il est possible d'intégrer certains éléments de cette dernière théorie dans un cadre plus général mais qu'elle sera vite transformée à la fois de l'intérieur par la reconnaissance d'une pluralité des formes du discours et de l'extérieur par son intégration partielle dans un schéma plus large qui vise à décrire un phénomène dans son intégralité.     

Last rights. In sickness and in health, more people are taking life's biggest decision away from doctors and into their own hands

When dying is all that awaits them, more and more people are choosing certain death now rather than uncertain life on medical support systems. But the decision seldom comes easy, as a Newsweek reporter discovers during three weeks with the doctors, nurses, patients and families in an intensive-care ward. A best-selling guide to suicide fires debate over when it is right to let life go--and who should make that choice when the patient no longer can.     

Money madness. Are private psychiatric hospitals resorting to kidnapping in their quest for paying patients?

In their zeal for lucrative insurance reimbursement, some private psychiatric hospitals seem to have gone over the edge themselves. A number of these institutions, critics charge, use outright coercion to commit and retain patients. Now some formerly abducted "recruits" are fighting back with lawsuits.     

Government health policy and hospital labor costs: the effects of wage and price controls on hospital wage rates and employment

This study examines the rapid growth of hospital wage rates and employment levels over the past decade, with particular attention to the period 1971-73, when wage and price controls were in effect throughout the economy. The analysis shows that the hospital regulations under the Economic Stabilization Program reduced real hospital wages below what they would have been in the absence of controls; a similar but smaller effect of the controls on hospital employment levels is also shown. This suggests that if the current HEW proposal for hospital cost containment is enacted, its impact would be a significant decrease in the rate of growth of hospital wages and employment.