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41.
This study investigated and evaluated the safety margins of the continuous long duration (up to 30 min) effect of the TASER X26 waveform, using a Sus scrofa model. Long duration continuous stimulus has not been evaluated on humans or human surrogates prior to this study. Swine were used as models due to similarities with humans in their skin and cardiovascular systems. Very long duration was used to determine both exposure dose and possible adverse physiological effects of dose. The trial began with an application of 10 min, and subsequent animals received increasing exposure time up to a survived maximum duration of 30 min. At the onset of this work, it was hypothesized that there would be a time limit after which most animals would not survive consistent with increased dose response. However, this hypothesis was not supported by the experimental results. All animals (10 of 10) survived up to 3 min. Seven of the 10 animals survived up to a 10‐min exposure and 3 of 5 animals with a 30‐min target exposure survived the full exposure. Surviving animals were recovered and observed for 24 h, with no postrecovery deaths. This suggests that swine (based on physiology) will not experience a fatal event when exposed to the TASER X26 for a continuous 3 min. Conclusions regarding longer duration (10–30 min) are not as certain due to the small sample sizes at these time intervals.  相似文献   
42.
The tech stock crash of 2000 discredited the new economy as business model. This article introduces a journal special issue which takes up the challenge of putting new economy developments into this post-crash perspective and establishing long-run continuities, without discounting the importance of what happened. This article opens the debate by highlighting two themes in the articles that are collected together in the special issue: first, it discusses what was and is the new economy in the USA; second, it examines the relevance and resonance of the new economy in Europe.  相似文献   
43.
In the pages of the daily financial press, 'shareholder value' is a loose rhetoric. For business consultants who sell financial metrics and implementation, shareholder value is also a product and a promise that purposive management action will be rewarded. This paper begins by considering the consultant's promise and the more guarded academic responses. It then presents empirics on micro performance and the meso limits to shareholder value and argues that most corporate managements cannot easily deliver what consultants promise and the capital markets demand. The paper ends by taking a broader view of value-based management as part of a process of financialization. If the results are contradictory and disappointing, a persistent gap between expectations and outcomes can nevertheless drive management behaviours, which change the world.  相似文献   
44.
Invalid voting, meaning blank and spoiled ballots, is a regular phenomenon in democracies around the world. When its share is larger than the margin of victory or greater than the vote share of some of the large parties in the country, invalid voting becomes a problem for democratic legitimacy. This article investigates its determinants in 417 democratic parliamentary elections in 73 countries on five continents from 1970 to 2011. The analysis shows that enforced compulsory voting and ethnic fragmentation are strong predictors for invalid voting while corruption has less impact. Our findings suggest that the societal structure is crucial in understanding invalid voting as a problem for democratic legitimacy because greater social diversity seems to lead to either a greater rate of mistakes or lesser attachments of social groups to the democratic process. Thus, rising levels of invalid voting are not only concerning in themselves but also for the divisive factors driving them.  相似文献   
45.
Poisoning may also lead to both coma and multiple organ failure, also in youngsters without a known major medical history. As not all toxic agents are routinely screened when a poisoning is suspected, it is useful to consider less frequently encountered poisons in certain cases. We describe the occurrence of asystole and multiple organ failure which occurred in a young man after a suspected tramadol overdose. The tramadol concentration on admission in the ICU was indeed 8 microg/ml (mg/l), far above the therapeutic range. Subsequently, the patient developed severe acute liver failure, finally leading to death. Post-mortem toxicology did not reveal any other poison responsible for this unfavourable course as only very high serum and tissue tramadol and desmethyltramadol concentrations were found. Only a few fatal poisonings attributable to tramadol alone, as observed in our case, have been reported. An overview of these cases is presented.  相似文献   
46.
International Journal for the Semiotics of Law - Revue internationale de Sémiotique juridique -  相似文献   
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Bereits seit 1991 existiert das übereinkommen zum Schutz der Alpen (Alpenkonvention, AK). Allerdings sind erst Ende 2002 die acht Durchführungsprotokolle zur AK und ein Zusatzprotokoll über die Streitbeilegung in Kraft getreten, weil drei Vertragsstaaten, darunter Deutschland, diese ratifiziert haben. In der Rahmenkonvention verpflichten sich die Vertragsparteien, „unter Beachtung des Vorsorge-, des Verursacher- und des Kooperationsprinzips eine ganzheitliche Politik zur Erhaltung und zum Schutz der Alpen unter ausgewogener Berücksichtigung der Interessen aller Alpenstaaten, ihrer alpinen Regionen sowie der Europ?ischen Union unter umsichtiger und nachhaltiger Nutzung der Ressourcen“ sicherzustellen (Art. 2 Abs. 1 AK). Nun geht es darum, die AK und ihre Protokolle umzusetzen, d.h. auf der Ebene des V?lkerrechts, aber auch auf nationaler Ebene durch Anpassung der nationalen Rechtsvorschriften sowie durch Anwendung und Auslegung der Konvention seitens der nationalen Beh?rden und Gerichte zu verwirklichen. Der nachfolgende Beitrag liefert einen überblick über Inhalt und Bedeutung der AK und ihrer Protokolle, ordnet die Konvention in das Umweltv?lkerrecht ein und befasst sich mit den Konsequenzen für das innerstaatliche Recht.  相似文献   
49.
States that choose to involve themselves in an ongoing dispute do so by choosing to align with or against one of the original disputants. What factors lead states to prefer to help one side over the other? We consider the effect of the disputants' power, political and economic institutional similarities between each disputant and the aligning state, and formal alliance commitments between each disputant and the aligning state on these alignment choices. We evaluate these expectations empirically by examining the alignment choices of states that joined with one side or another in a Militarized Interstate Dispute during the period of 1816 to 1986. The results indicate that regardless of regime type, institutional similarities matter to the aligning state's decision. We also find that power concerns matter only to autocracies; democracies do not seem to base their alignment choices on the power of the sides in the dispute. Finally, the evidence indicates that the alignment choices of democracies cannot be anticipated by their prior alliance commitments, although the alignment choices of autocracies can. These results suggest interesting implications for research on the democratic peace, the determinants of threat in the international system, and the impact of selection effects. The consistent empirical evidence that institutional similarity affects alignment decisions also increases our confidence that future investigations of institutional similarity generally, rather than an exclusive focus on joint democracy, will prove fruitful.  相似文献   
50.
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