Determination of polymorphism at eight STR loci in the Croatian population using automated detection

Population study was carried out on the sample of 167 unrelated donors from the wider area of the Croatia's capital, Zagreb, using the short tandem reapet (STR) loci: TH01, VWFA31, FES/FPS, F13A01, D1S1656, D12S391, D18S535 and D22S683.     

Exploring the Inner Life of the Party: A Framework for Analysing Elite Party Culture

This article presents a framework for analysing party‐organisational culture, with a special focus on the elite level. The framework is based on an interpretation of Mary Douglas’ Grid/Group model, and is empirically supported by an extensive study of the seven party groups in the Swedish parliament. The model identifies two fundamental cultural dimensions: the level of submission by individual group members to the group as a collectivity; and the principle that dictates the distribution of status and prestige within the party (a distribution here correlating with views on knowledge). The study shows that the parties distribute themselves on the cultural map in ways that do not coincide in any straightforward way with other well‐known variables of party politics, such as ideology, origin or size. The methodological innovations presented in this article pave the way for a new framework for analysing party politics in which hitherto neglected aspects of party organisation are highlighted.     

A fatal interaction: The role of the victim and function of aggression in intrafamilial homicide

Abstract

This study examines the interaction between the victim and offender during intrafamilial homicide. It is hypothesised that in order to understand the fatal consequences of the interaction, a psychological model must take into account both the role of the victim, as either a significant person or non-significant object, and the function of the aggression, as either instrumental or expressive. The combination of these two proposed facets gives rise to four hypothesised styles of intrafamilial homicide. This hypothesis was tested by analysing 191 intrafamilial homicide cases from the Chicago HITS database. Fifty two crime-scene actions were analysed using Smallest Space Analysis which revealed four distinct thematic clusters of variables. These themes corresponded to the hypothesised facets of victim role and function of aggression. Two related to expressive acts, (a) those murders where the offender kills multiple members of his family and subsequently takes his own life, and (b) cases where the victim is not treated as a significant person in the interaction but is simply used as a target for the offender's rage. The other two relate to instrumental acts, (c) those murders that are a culmination of years of abuse in which the offender sees the killing as the only means of escape, and (d) homicides where the victim is seen as an obstacle to the offender achieving a goal and is removed.

A further test of the validity of these four themes in describing distinct forms of interaction within intrafamilial homicide was to examine the proportion of cases which could be classified according to the framework. The hypothesis that each relationship would map onto just one of the interactional styles was tested by χ² which confirmed that such exclusive relationships existed at the p < .001 level of significance. This has theoretical as well as practical implications in that in using this method of classification it may be possible to infer which family member is responsible for killing their relative.     

Disordered personalities at work

Current categorical classification systems of personality disorders (PDs) remain widely used amid growing evidence that argues against the conceptualisation of PDs as independent, discrete entities. Adopting the dimensional perspective of Morey et al. (Journal of Personality Assessment, 49, 245–251, 1985), this study compared PD traits across forensic, psychiatric and “normal” senior business manager samples. There was particular interest in the relative representations of elements of PD closely associated with psychopathic PD because of research suggesting that some “psychopaths” operate within mainstream society, and links that have been made between elements of these so-called “successful” psychopaths, and characteristics associated with success in senior business management roles. The dimensional Minnesota Multiphasic Personality Inventory Scales for DSM III Personality Disorders (MMPI-PD) were shown to be internally consistent for the “normal” sample. Evidence for the qualitative equivalence of the four PD profiles emerged. The PD profile of the senior business manager sample was found to contain significant elements of PD, particularly those that have been referred to as the “emotional components” of psychopathic PD. The findings provide strong support for the continuous distribution of personality disordered traits.     

Examining the psychopathology of incarcerated male firesetters using the Millon Clinical Multiaxial Inventory-III

Research to date has been equivocal on the relationship between firesetting and psychopathology and has been impeded by studies lacking adequate control samples. The present study examined psychopathology in a sample of incarcerated adult male firesetters (n = 112) and prison controls (n = 113) using the Millon Clinical Multiaxial Inventory-III. Firesetters demonstrated multiple elevated scores on personality and clinical syndrome scales. Logistic regression showed that the borderline personality scale was the strongest personality scale discriminator between firesetters and controls. Major depression and drug dependence were the strongest clinical syndrome scale predictors. However, both clinical syndrome scale predictors appeared to be mediated by borderline personality scores indicating that firesetters are best characterized by responding indicative of borderline personality traits rather than other psychopathological deficits. The results suggest that, relative to other offenders, firesetters face challenges with impulse control, affect regulation, stability of interpersonal relationships, and self-image.     

Phenibut screening and quantification with liquid chromatography–tandem mass spectrometry and its application to driving cases

An analytical strategy for identification by an LC–MS/MS multitarget screening method and a suitable LC–MS/MS based quantification were developed for the psychotropic drug phenibut. The samples analyzed were collected during traffic control and were associated with driving under the influence of drugs. A positive sample for phenibut was identified in a single case of driving under the influence. The quantification revealed a drug concentration of 1.9 μg/mL. An interaction with blood alcohol (BAC = 0.10%) was discussed as the explanation of the way of driving and deficit manifestations observed (swaying, nystagmus, quivering of the eyelid, and reddened eyes). According to the available information, the quantified phenibut concentration could be explained by an intake of four tablets (self-reported) during the day containing 250 mg of the drug. Chromatography was performed with a Luna 5 μm C18 (2) 100 A, 150 mm × 2 mm analytical column, and a buffer system consisted of 10 mM ammonium acetate and 0.1% acetic acid (v/v) included in mobile phases marked as A (H₂O/methanol = 95/5, v/v) and B (H₂O/methanol = 3/97, v/v). An effective limit of detection (LOD = 0.002 μg/mL) could be achieved for the multitarget screening method. The quantification of phenibut was performed on a second LC–MS/MS system with LOD/LOQ values of 0.22/0.40 μg/mL. Since phenibut quantification data are rare, the presented information can be used with caution for evaluation of positive cases in the future.