咳喘速平颗粒剂对慢性支气管炎大鼠支气管和肺形态学的影响

目的:观察咳喘速平颗粒剂对慢性支气管炎大鼠的气管、肺组织形态学变化的影响.方法:采用气管内注入脂多糖复制大鼠慢性支气管炎模型,分模型组、阳性对照组、咳喘速平(小)组、咳喘速平(大)组.结果:模型组可见支气管上皮大面积坏死、脱落,细支气管管腔扩大,管壁及其周围见大量淋巴细胞浸润,部分肺泡间隔断离呈肺气肿改变.阳性对照组可见支气管上皮细胞少量坏死脱落,管壁与周围淋巴细胞浸润,管腔无明显扩张,肺泡上皮完整,无明显病理改变.咳喘速平(小)组可见支气管上皮细胞片状坏死、脱落,伴上皮细胞灶性增生,管壁增厚伴大量淋巴细胞浸润.咳喘速平(大)组可见支气管上皮细胞基本完好,无明显的坏死和增生,伴少量的淋巴细胞浸润.5组之间支气管黏膜坏死(炎性浸润)存在显著性差异(P<0.01).结论:咳喘速平颗粒剂可减轻大鼠慢性支气管炎的临床表现,形态学检查显示用药后受损的支气管黏膜上皮和肺组织趋向好转,表明咳喘速平颗粒剂对大鼠慢性支气管炎具有较好的治疗作用.     

Exchange rate volatility in high inflation economies: An econometric study of Poland and Brazil

This paper analyses exchange rate series for Poland and Brazil. The Polish series, related to the period soon after the first liberalizing measures, presents a high volatility which is not accounted for by some selected ‘fundamentals’. The Brazilian series, though also keeping evidence of excessive volatility, is cointegrated with fundamentals similar to those of the Polish case. This raises the issue of a learning process taking place during persistent inflations. Unsuccessful one-shot stabilization plans can reinforce this process, leaving a lasting imprint in the excessive volatility pattern. The message seems clear, though maybe not easy to implement: agents take some time to learn to live in non-stable environments; to avoid this by one-shot measures — if unsuccessful — can have a very high cost and pre-empt future corrections.     

"Bru-u-u-uce": The simple economics of mob goods

This paper provides a pure economic rationale for chronic excess demand for tickets to events like rock concerts. The model focuses on "mob goods", which are consumed jointly with crowd reaction, or "noise". Whereas the primary commodity is provided by the seller, the joint product is provided collectively by buyers. If propensities to make noise are inversely correlated with reservation prices and a capacity constraint applies, excess demand (queuing) is a necessary condition for profit maximization. One important implication is that anti-scalping laws may be welfare-increasing. The paper explores other applications in professional sports, restaurants, and on-stage theatre.     

The political economy of targeting

One of the most widely used method of targeting is to reduce welfare benefits as income rises. Although the need for such targeting is clear enough, it also entails two important difficulties. Firstly, the prospect for the recipients of losing part of their benefits if they were to earn more can be a deterrent to work harder. Secondly, by reducing the number of recipients, targeting reduces the political support for taxation and redistribution. The purpose of this paper is to study the voting equilibrium of the degree of targeting and the level of taxation in an economy where labour supply is variable. The analysis reveals that targeting may be fatal for redistribution even though it rejects strictly less than the richest half of the population, and that it is not possible for a coalition of the extremes to form and reject the middle income group from the welfare system. Moreover, because targeting affects labour supply, we find that Pareto improvements are possible when targeting is either “too low” or “too high”. We also find that voting simultaneously over taxation and targeting is favourable to the poor in the sense that they can converge to their most-preferred policy by successively forming a majority coalition with the rich to increase targeting and with the middle to increase taxation.     

Issue news and electoral volatility

Abstract. This article shows that issue coverage in the media partly explains both the political landslide at the 1994 elections in the Netherlands and the political continuity in the 1994 elections in Germany. Theories of issue voting guided the research. Issue ownership theory maintains that voters will remember which party has the best record of solving problems in emphasized issue areas. Proximity models and directional models suggest that voters' own issue positions will be compared to the perceived issue positions of parties. A longitudinal content analysis of ten newspapers and five television news programmes was performed to ascertain selective issue emphasis and the issue positions attributed to parties. Election outcomes and weekly opinion polls were used to measure the volatility of the vote.     

Asbestos body burden in decomposed human lungs

The authors discuss the influence of postmortem tissue decomposition on the lung asbestos body (AB) burden, with the aim of evaluating the reliability of data obtained from autopsies performed for medicolegal purposes several months after deaths in possible connection with asbestos-related pathology. Eight autopsy cases were selected, each one with occupational exposure considered very probable on the basis of the history or pathologic findings. In each case the AB concentrations were assessed soon after death in one lung and after periods of 1 to 18 months in the others, which had been stored in sealed containers without fixation. AB concentrations consistently decreased with time in rotten lungs. The counts in some cases became negative a few months after death, even in cases with very high AB counts at first examination. It may be reasonably inferred that, in putrefied lungs from corpses exhumed after months of internment, the counts in digested tissues and the screening of histologic sections for AB may give false-negative results.     

Psychological mindedness and abstract reasoning in late childhood and adolescence: An exploration using new instruments

This study introduces two new measures of psychological mindedness, applying them in a study of the growth of abstract thinking in children and adolescents in a developmental design. The capacity to achieve psychological understanding of the self and of others involves comprehension of the motives, attitudes, and characteristics of the self and others. Psychological mindedness toward the self (PS) and toward others (PO) may be seen as complex cognitive capacities that should show a pattern of related development in childhood. Three groups of 60 fifth, eighth, and twelfth graders completed two measures of formal operations and two instruments to assess the two components of psychological mindedness. We find that psychological mindedness and abstract thinking both increase significantly with age, although the relationship between them is complex and varies with gender and age. Because the development of abstract reasoning skills does not correlate with the development of psychological mindedness in a simple way, a more complex model is necessary, taking age and gender differences into account. Performance on the two measures of psychological mindedness is found to be largely unrelated, suggesting that these are two different psychological skills. Implications of these findings are discussed, with special reference to education, peer counseling, and psychotherapy.Received Ph.D. from University of Michigan and psychoanalytic training from The Michigan Psychoanalytic Institute. Main research interests are psychoanalytic theory, the therapeutic alliance, and insight and self-observation.Received Ph.D. from University of Michigan. Main research interests are adolescent development, peer counseling, short-term psychotherapy, and the psychology of women.Received M.A. from The University of Michigan. Main research interests are infant mental health and attachment theory.Received M.A. from The University of Michigan. Main research interests are gender identity and children of divorce.Received B.A. from The University of Michigan. Main research interests are gender issues and adolescent development.     

Legal Theory and Sociological Facts

The authors investigate MacCormick and Weinberger's claim that the Institutional Theory of Law provides a conceptual framework for the study of legal phenomena from a socio-legal point of view. They evaluate this claim by confronting both the Institutional Theory of Law and Weinberger's theory of action with two approaches in socio-legal theory, i.e. the instrumentalist and the constitutive approach. The conclusion is that the Institutional Theory of Law lends itself to empirical research from an instrumentalist perspective, for both place the concept institution in the context of law. Weinberger's theory of action may provide a basis for empirical research from a constitutive perspective. The authors make some suggestions for refinement of Weinberger's theory of action in order that the relation between institutions and action can be labeled dynamic.