Increased sensitivity for amplified STR alleles on capillary sequencers with BigDye XTerminator™

Free fluorescent dyes from PCR primers or amplification products can interfere with the interpretation of STR alleles in an electropherograph especially when the profiles have a low signal intensity. These artefacts can be removed by using a simple procedure based on BigDye^® XTerminator™. This procedure requires limited amounts of PCR product, allows to do several loadings on a capillary sequencer starting from the same purified PCR product and also increases the sensitivity for detection of less amplified loci.     

Competence-Related Abilities and Psychiatric Symptoms: An Analysis of the Underlying Structure and Correlates of the MacCAT-CA and the BPRS

The current study used confirmatory factor analysis to examine the factor structures of two instruments commonly used in the assessment of competency to stand trial--the MacArthur Competence Assessment Tool--Criminal Adjudication (MacCAT-CA) and the Brief Psychiatric Rating Scale (BPRS). Results revealed support for the three-subscale factor structure of the MacCAT-CA defined by the authors of the instrument; for a slightly altered three-factor structure defined by Zapf, Skeem, and Golding (2005, Psychological Assessment, 17, 433-445); and for the four symptom clusters of the BPRS as defined by Hedlund and Vieweg (1980, Journal of Operational Psychiatry, 11, 48-63). In addition, exploratory factor analysis of all 24 items of the BPRS revealed a five-factor structure. Correlations between psychiatric symptoms, symptom clusters, and competence-related abilities were also examined using the previously identified and the newly identified factor structures of the MacCAT-CA and the BPRS. Significant relations between symptoms and psycholegal abilities are discussed.     

The concept of forensic emergency medicine as illustrated by an unusual complication of pulmonary artery catheterization

Forensic pathologists are regularly confronted with emergency and invasive medical procedures performed on critically ill or traumatized patients. Basic knowledge of such procedures and their possible complications is therefore mandatory in medico-legal practice. In this article, we describe a very unusual complication of pulmonary artery catheterization: through-and-through perforation of the carotid artery, initially without hemodynamic consequence. Death resulted from an aggravation of the preexisting cerebral edema (secondary to a craniocerebral trauma). The misplacement of the pulmonary artery catheter was clinically missed because the guidewire was initially deflected on the cervical spine towards the subclavian vein where the catheter--by chance--entered the circulatory system and followed its normal route further. The forensic importance of leaving all invasive medical devices in situ on a deceased person when a medico-legal autopsy is to be expected and the mutual interaction between emergency and forensic medicine (forensic emergency medicine) are discussed.     

Policy-making in a Restructured State: The Case of the 1991 Health Reform Policy in New Zealand

The pressure for efficiency and accountability that led to reform of public institutions worldwide has had implications for public policy-making as well as the management of public services. The difficulties of providing a coordinated and efficient policy process that can respond to the requirements of a more managerialist style of government were evident in New Zealand in the 1980s and early 1990s. The policy process in 1990–91 leading to the introduction of health reform proposals provides an illuminating case study of the tension between participation and speed, and between traditional pluralist and managerialist approaches to policy development. The implications of this for subsequent implementation are discussed.     

The Cerberus from Warringah: F.A. Bland and the Renaissance of the Public Accounts Committee

In 1932 the Lyons UAP government suspended the operations of the Commonwealth parliament's public accounts committee, allegedly as an economy measure. The role of public accounts committees is, in principle, that of a non‐partisan reviewer of the public finances, but in this case the committee had diverged from its charter and become involved in politics and policy. Twenty years later, the Menzies government resurrected the committee. A crucial figure in its re‐establishment was F.A. Bland, variously a professor of public administration, member for Warringah in the House of Representatives, and a significant public intellectual from the 1920s to the 1960s. Today Bland is almost forgotten but the role the re‐established committee played in its early days was largely a reflection of his interests and commitments.     

How Is Criminal Justice Related to the Rest of Justice?

Are principles of criminal justice derived from a broader conception of justice, or does criminal justice involve some of its own distinctive principles such that it is not—for example—an aspect of distributive justice? Examining considerations regarding luck and desert provides an illuminating approach to this issue. The notion of desert has largely been excised from a great deal of recent political theorizing, and in particular, it has been eliminated from many influential conceptions of distributive justice. It is widely held that the pervasiveness of luck renders desert inappropriate to contexts of distributive justice, and incompatible with the freedom and equality of persons in a just political community. Should considerations of desert also have a minimal role in criminal justice—where they seem to still be important? Are considerations of desert in the context of criminal justice consistent with persons being free and equal participants in a just political community? How are principles of criminal justice related to principles of distributive justice and political justice in an overall just society? Many scholars agree that criminal justice presupposes an adequately just society. Still, that leaves open just how criminal justice relates to justice overall. That is the present topic.     

A Tall Order

Despite expectations of a far closer outcome,the UK general election on December 12,2019 resulted in a clear victory for the Conservative Party under Boris Johnson.It continues its history as the most successful electoral force in modern European history.Despite the doomsayers,Johnson now has a clear majority and has already flexed his muscle by passing the legislation to take the UK out of the EU on January 31.Barring complete disaster for him and his government this will now happen.     

Quantum Sensing's Potential Impacts on Strategic Deterrence and Modern Warfare

This article examines the impact of quantum sensing on strategic deterrence and modern warfare. It has two related objectives. The first is to highlight quantum sensing as an important area of research for the policy communities considering the role of emerging technologies on strategic deterrence and countering weapons of mass destruction. The second aim is to present the potential warfighting implications of quantum sensing if employed by either the United States or its adversaries. While quantum sensing technologies offer opportunities to transform modern warfare, they also present challenges and risks. The article contends that the quantum sensing investment, research, and development should be prioritized within the Department of Defense's quantum science modernization agenda to ensure that the U.S. military does not cede technological advantage to competitors, such as the People's Republic of China, who are actively investing in quantum sensing applications that could upend the United States’ existing deterrence and warfighting capabilities.