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331.
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This article addresses three critical questions central to many donor funded programmes which seek to enable pro‐poor reform and growth. In the context of Bangladesh, the research asks first, does the civil service has a role in promoting change of this kind? Second, can a senior civil service development programme succeed in creating reform minded civil servants? And, third, if so how might the contribution be made both more substantive and of value? These questions are addressed systematically through a literature review and evidence drawn from Managing at the Top (MATT 2)—a DFID funded programme. Some tentative conclusions are drawn in the final section. Copyright © 2009 John Wiley & Sons, Ltd.  相似文献   
333.
Nuclear DNA was extracted from human telogen hairs from 60 individuals. Six to nine hairs from each individual were individually extracted. The amount of DNA recovered from each individual varied greatly, and most samples yielded a quantity of 550 pg or less per hair. A selective extraction buffer was used to remove epithelial cell DNA and the amount of exogenous DNA was determined. DNA was also quantified by real time PCR using three different sized amplicons targeting an Alu sequence. The results were used to determine the state of degradation of the extracted DNA. Different quantities of sample (<100 pg, 100-500 pg, >500 pg) were amplified with the Miniplex kits to determine the minimum DNA template required for successful amplification. DNA recovered from hair showed degradation; however, partial profiles were obtained for those samples containing at least 60 pg using MiniSTRs.  相似文献   
334.
Three multiplex PCRs were developed for the analysis of 14 single-copy and 4 multi-copy Y chromosome Short Tandem Repeat (STR) loci routinely used by several public genealogical databases. These assays were used in addition to PowerPlex® Y for the analysis of 245 DNA samples from a genealogical project. In total 244 different haplotypes composed of 37–40 alleles were identified with one haplotype identical between two males with the same surname. The multi-copy loci DYS464 and DYS724 were the most polymorphic with a gene diversity of at least 0.964. The use of DYS454 and DYS455 can be questioned as these loci had the lowest gene diversity (0.039 and 0.269, respectively).  相似文献   
335.
The global production of knowledge is grossly skewed to the northern Anglophone world (Hogg et al. in International Journal for Crime, Justice and Social Democracy, 6(1), 1–7, 2017; Connell 2007). It should be no surprise therefore that criminology’s origin stories are derivative of northern experiences, yet generalised as universal theories of crime causation. In this article, we argue that the origin stories of criminological theory translated the ‘darker’, ‘hairier’ and ‘muscular’ masculinities of the global south into prototypes of dangerousness. These prototypes were first articulated as scientific claims in the nineteenth century works of Lombroso, but have been refined and embedded in mainstream criminological discourses well into the present, mainly through the quantitative study of social disorganisation, ‘race’ and racialised masculinities as variables in crime causation. The paper concedes that while deeply troubling expressions of violent masculinity exist now and in the past in the global south, it is mistaken to conceive this violence simply as expressions of atavism or social disorganisation associated with a less civilised world. On the contrary, this paper argues that the violence of colonality itself has had, and continues to have, a criminogenic impact on the present.  相似文献   
336.
Snitching and the Code of the Street   总被引:1,自引:0,他引:1  
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337.
338.
Detection of specific meningococcal capsular polysaccharide (CPS) in postmortem blood permits rapid diagnosis of meningococcemia and differentiation from pneumococcemia and septicemia caused by Haemophilus influenzae Type b. We present studies validating application of latex agglutination assay for CPS on blood samples collected at autopsy, delineate the circumstances when CPS testing is indicated, and illustrate the usefulness of this procedure by several recent cases. Blood samples from victims dying of injury or disease other than infection were examined to determine whether the postmortem interval, bacterial contamination, anticoagulants, or delay in testing would result in false positive assays. Series 1 samples, collected so as to minimize bacterial contamination, were immediately submitted for assay. Series 2 evaluated the effect of adverse conditions of collection, anticoagulation, and prolonged sample storage. Despite extended postmortem intervals of up to 14 days, heavy bacterial contamination, prolonged storage at 4 degrees C, deep hemolysis, and presence of anticoagulants, false positive assays were seldom observed.  相似文献   
339.
Amphetamines are popular drugs of abuse, particularly among youngsters and at dance scenes. Cardiotoxicity (manifested as cardiomyopathy, acute myocardial infarction/necrosis, heart failure, or arrhythmia) after the recreational (mis)use of amphetamine and its synthetic derivatives has been documented but is rather rare. Amphetamine-related cardiac fatalities are even more rare. We present 6 cases of young persons who died unexpected after the chronic abuse of amphetamines. Death was not attributed to a lethal intoxication but to an acute myocardial necrosis, a right ventricle rupture, a cardiomyopathy, or an arrhythmia. Two of the deceased persons presented prior to their death to the emergency department, but their complaints were not considered (probably due to their young age) to be of cardiac origin. One case was a sport-related fatality where medical screening failed to identify the underlying cardiac pathology or the amphetamine abuse, and 1 case was a so-called idiopathic dilated cardiomyopathy where substance abuse was not considered by the treating physician. We think that amphetamine-associated cardiotoxicity is a rare but probably genuine entity that should be considered both in forensic and clinical/emergency medicine because of its potential medicolegal implications.  相似文献   
340.
What influence do the personal belief in a just world (i.e., the perception that one usually gets what one deserves) and different kinds of causal attributions have on adjustment to sexual violence? Using a sample of N = 62 victims of sexual aggression (mean age = 21.7) it was shown that respondents were better able to adjust to their experience of sexual violence the higher their personal belief in a just world. Moreover, the more respondents attributed their victimization to situational circumstances (external attributions) and the less they attributed their victimization to their character and personality (characterological self-attributions), the less they felt distressed by past victimization. The degree to which participants attributed their victimization to their own concrete behavior (behavioral self-attribution) was not related to their adjustment. Further analyses showed that the influence of the personal belief in a just world was mediated by the three attribution styles. Additionally, the adaptiveness of external attributions was moderated by participants’ just world belief.  相似文献   
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