Gas chromatographic-mass spectrometric analysis of buflomedil hydrochloride in biological samples after acute intoxication.

Two cases of acute intoxication of buflomedil hydrochloride are reported. The analysis of this compound was performed by an Extrelut extraction followed by a gas chromatographic-mass spectrometric determination. Analytical parameters of linearity, reproducibility and specificity were satisfactory.     

文化性的缺失—论课程的文化锁定现象

课程起源于化传承的需要，传递、复制、再生产社会化是学校课程唯一不变的使命。在课程发展中形成了特定的化锁定现象。它造成了课程应具有的自的化品性及其所必然引发的内在的、独立的价值标准与宗旨的消解。课程成了现实社会主流化的“代言人”。它具有诠释、粉饰及原样传递的职责，却无反思、批判、创新的品质。学校教育的工具品性、灌输与训练机制、教育教学理论的学术品质等，都是课程化锁定现象所造成的化性缺失的必然结果。揭示课程化性缺失的病理表征，是使课程由化的工具存在转变为化的主体存在的重要前题。     

The use of isoelectric focusing to identify rhinoceros keratins.

Keratins represent the principal structural proteins of hair. They are also found in horn, nail, claw, hoof, and feather. Hair and nail samples from human and canine sources and hair samples from mule deer, white tail deer, cat, moose, elk, antelope, caribou, raccoon, and goat were studied. Parrot and goose feathers were also analyzed. Keratins are polymorphic, and species differences are known to exist. Proteinaceous extracts of deer and antelope antlers and bovine and rhinoceros horn were prepared by solubilizing 10 mg of horn sample in 200 microL of a solution containing 12M urea, 74mM Trizma base, and 78mM dithiothreitol (DTT). Extraction took place over a 48-h period. A 25-microL aliquot of extract was removed and incubated with 5 microL of 0.1 M DTT for 10 min at 25 degrees C. Keratins were then separated by isoelectric focusing (IEF) on 5.2% polyacrylamide gels for 3 h and visualized using silver staining. At least 20 bands could be observed for each species studied. However, band patterns differed in the position of each band, in the number of bands, and in band coloration resulting from the silver staining process. Horn from two species of rhinoceros was examined. For both specimens, most bands occurred in the pH range of 4 to 5. Although similar patterns for both species were observed, they differed sufficiently to differentiate one from the other. As might be expected, the closer two species are related phylogenetically, the greater the similarity in the IEF pattern produced from their solubilized keratin.(ABSTRACT TRUNCATED AT 250 WORDS)     

A discriminant function analysis of deciduous teeth to determine sex

Studies of deciduous teeth have concluded that crown size differences in these teeth between males and females are not reliable sex discriminators, in contrast to such differences in permanent teeth. This study measured the mesiodistal and faciolingual crown diameters of all deciduous teeth, as well as those of the permanent first molars, of 162 children from the Burlington Orthodontic Growth Study, conducted earlier in Burlington, Ontario, Canada. All 40 deciduous tooth diameters (20 mesiolingual and 20 faciolingual) were significantly different between the sexes, as were the permanent tooth diameters. Using three to five measurements of deciduous teeth, discriminant analyses of several samplings of these children produced discriminant functions in which 76 to 90% of the holdout samples were correctly classified by sex. Combinations of deciduous and permanent measurements were used to classify 83 to 85% of the holdout samples correctly. When compared with published data on other sample populations, the Burlington group is the most dimorphic for deciduous teeth and is within the range of permanent tooth dimorphisms of other populations. The level of classification accuracy, when using discriminant analysis of the deciduous teeth, can approach the accuracy levels of analysis using the permanent teeth.     

Visa Diplomacy

The consular element of national diplomatic power plays an essential, but often overlooked role in international relations. This is unfortunate, since the process of globalization places increasing importance on so-called “low politics”—trade, commerce, tourism, migration—all traditional consular areas of interest. This study examines the visa component of consular diplomacy as an integral device in the conduct of international relations. The simple visa serves an important purpose in international relations and is a well-used, but little studied, instrument of foreign policy in today's system of sovereign states.

In this article, “visa diplomacy” is defined as the use of visa issuance or denial at an individual, group, and interstate level, to influence another state's policies. Although possessing limitations, visa diplomacy is an available signaling and retorsion instrument which makes it a viable policy option in the arena of international affairs. At the operative level, it links an individual or group to its sovereign country and respective national policies. Denial or issuance at the individual or group level can have outcomes on overall interstate interactions as illustrated in the cases selected for this study. The conclusion assesses where the use of visa diplomacy seems most effective in international relations.