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Bill M Gill P Curran J Clayton T Pinchin R Healy M Buckleton J 《Forensic science international》2005,148(2-3):181-189
Several years ago, a theory to interpret mixed DNA profiles was proposed that included a consideration of peak area using the method of least squares. This method of mixture interpretation has not been widely adopted because of the complexity of the associated calculations. Most reporting officers (RO) employ an experience and judgement based approach to the interpretation of mixed DNA profiles. Here we present an approach that has formalised the thinking behind this experience and judgement. This has been written into a computer program package called PENDULUM. The program uses a least squares method to estimate the pre-amplification mixture proportion for two potential contributors. It then calculates the heterozygous balance for all of the potential sets of genotypes. A list of "possible" genotypes is generated using a set of heuristic rules. External to the programme the candidate genotypes may then be used to formulate likelihood ratios (LR) that are based on alternative casework propositions. The system does not represent a black box approach; rather it has been integrated into the method currently used by the reporting officers at the Forensic Science Service (FSS). The time saved in automating routine calculations associated with mixtures analysis is significant. In addition, the computer program assists in unifying reporting processes, thereby improving the consistency of reporting. 相似文献
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Kieran Mitton 《冲突、安全与发展》2008,8(2):193-222
The conflict between the Revolutionary United Front (RUF) and the Sierra Leonean government represents a highly instructive study for reintegration projects. Far from being a conventional political insurgency readily lending itself to peaceful political transformation, the RUF possessed within the ranks of its young and brutalised recruits a fundamental rejection of Sierra Leone's political structures. As such, Sierra Leone presented a unique challenge for reintegration efforts, requiring not only the immediate reconciliation of ex-combatants with victims and civil society, but also the long-term political incorporation of a group of youths defined by their very disengagement from and distrust of the political system. This article argues that the Sierra Leone experience demonstrates that successful political reintegration does not simply amount to political participation per se, but rather requires specific forms of political participation, which reinforce the primacy of peaceful political interaction over and above other means for affecting change. In this regard, this article concludes that despite progress in many key areas, former fighters of the RUF have yet to be fully politically reintegrated. 相似文献
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AbstractThis paper explores the benefits of engaging with self-defined communities in Northern Ireland on the issue of sexual offending and argues the case for building on existing community structures, by identifying people with leadership skills and by empowering them with the knowledge, and with connections to statutory services, that will support public protection. We address the historical context in terms of the impact of the conflict on these communities and describe the role and experience of NIACRO working in Northern Ireland, in particular its Base2 project supporting people under threat. We reference the development of current statutory arrangements for Public Protection Arrangements for Northern Ireland (PPANI) and argue the case for preparing people in the community to receive and understand the messages promoted through PPANI on the basis of our belief that public education is most effective when the people receiving it are receptive. 相似文献