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91.
Robert K. Christensen Laurie Paarlberg James L. Perry 《Public administration review》2017,77(4):529-542
Public service motivation research has proliferated in parallel with concerns about how to improve the performance of public service personnel. However, scholarship does not always inform management and leadership. This article purposefully reviews public service motivation research since 2008 to determine the extent to which researchers have identified lessons for practice. The results of the investigation support several lessons—among them using public service motivation as a selection tool, facilitating public service motivation through cooperation in the workplace, conveying the significance of the job, and building leadership based on public service values. These results are important because they offer evidence that the field is coalescing around tactics that managers and leaders can use to address enduring concerns about employee motivation in the public sector. They also prompt us to articulate ideas that can guide a tighter integration of research and practice moving forward. 相似文献
92.
Zheng Zhang M.D. Meghan C. Burke Ph.D. William E. Wallace Ph.D. Yuxue Liang Ph.D. Sergey L. Sheetlin Ph.D. Yuri A. Mirokhin Ph.D. Dmitrii V. Tchekhovskoi Ph.D. Stephen E. Stein Ph.D. 《Journal of forensic sciences》2020,65(2):406-420
Recent reports have demonstrated that genetically variant peptides derived from human hair shaft proteins can be used to differentiate individuals of different biogeographic origins. We report a method involving direct extraction of hair shaft proteins more sensitive than previously published methods regarding GVP detection. It involves one step for protein extraction and was found to provide reproducible results. A detailed proteomic analysis of this data is presented that led to the following four results: (i) A peptide spectral library was created and made available for download. It contains all identified peptides from this work, including GVPs that, when appropriately expanded with diverse hair-derived peptides, can provide a routine, reliable, and sensitive means of analyzing hair digests; (ii) an analysis of artifact peptides arising from side reactions is also made using a new method for finding unexpected modifications; (iii) detailed analysis of the gel-based method employed clearly shows the high degree of cross-linking or protein association involved in hair digestion, with major GVPs eluting over a wide range of high molecular weights while others apparently arise from distinct non-cross-linked proteins; and (v) finally, we show that some of the specific GVP identifications depend on the sample preparation method. 相似文献
93.
For several years, the misuse of stimulant substances is increasingly observed both in the field of sport, to improve the functions of the body and therefore to be more performant, and also by non-athletes to make life more tolerable on a daily basis. Adrafinil, 2-((diphenylmethyl)sulfinyl)-N-hydroxyacetamide, is a drug designed for the treatment of narcolepsy by promoting an awakened state, and to treat alertness and neurological symptoms in the elderly. It is primarily metabolized in vivo to an active form, i.e. modafinil, 2-((diphenylmethyl)sulfinyl)acetamide. The World Anti-Doping Agency (WADA) banned these two drugs in sports in 2004. The authors report an authentic case involving adrafinil and modafinil. The laboratory was requested to test for adrafinil in a hair strand collected from a woman found in possession of vials of adrafinil and suspected of trafficking. A specific method was developed by liquid chromatography tandem mass spectrometry (LC-MS/MS). Unlike modafinil (varying from 6.8 to 13.9 ng/mg), adrafinil was not identified in the strand. The interpretation of the results was difficult because this is the first case describing human hair analysis. In order to be able to interpret the results, a self-administration study was conducted after an oral administration to a volunteer (200 mg) whose beard hair was collected 10 days after administration. The analysis of this specimen highlighted the presence of adrafinil at 0.8 ng/mg and modafinil at 0.5 ng/mg. These results demonstrate the dual identification of both compounds after a single consumption, even after administration of a low dose. According to these results, the analysis of the hair strand from the authentic case does not match with a consumption of adrafinil, in accordance with abuse of modafinil alone. Intelligence considered that this was a trafficking case of adrafinil, with no self-consumption. 相似文献
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托护(looked after)青少年是指父母无力监护、监护不力以及受到家庭虐待的青少年.这类由政府专门机构或寄养家庭收养的青少年,他们的心理健康问题复杂多样. 相似文献
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This article first considers the tenuous base on which the law of property in the body is founded, and then discusses the practical results of this in the light of the recent furore surrounding events at Bristol and Alder Hey. The authors suggest that neither the consent-based model followed by the official inquiries into these events nor a possible policy based on a full-blown property model adequately cover the private rights of an individual's next of kin or the right of the public to an efficient and reliable pathological service within the NHS. Rather, they propose that a combined model in which a 'cascade of possession' for the recognition of various property interests is initiated by assent on the part of the next of kin and terminates in full possession of the body vested in the executor for the purposes of its disposal. The authors recommend further that any reform of the law should apply property rights to body parts taken from both the living and the dead. 相似文献
100.
Charles L. Gutshall David P. Hampton Jr. Paul C. Stein Thomas J. Broxtermann 《Police Practice and Research》2017,18(5):463-477
The occupational stress of police officers, and its’ effect on working memory and other psychological and behavioral factors over a two-week work period have been investigated. Cognitive performance and stress levels were examined at pre and post work cycles by using a memory test and several self-reporting surveys, each designed for a specific purpose and to gauge a particular set of behaviors and personality traits. The police officers were assigned to patrol duties at the time of the investigation and placed into three groups based on years of service (1–20 years). The results of the investigation identified a deficit in working memory in Junior, Veteran, and Senior Officers, based on the Ray Osterreith Complex Figure Scores at Baseline (pre-stress) vs. Test Day (post-stress). The other survey tools measuring stress impact on personality and behavior, did not demonstrate any statistical differences in the responding groups of officers in their survey performances. 相似文献