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Paternity testing is being increasingly requested with the aim of challenging presumptive fatherhood. The ability to establish the biological father is usually based on the genotyping of autosomal short tandem repeat (STR) in alleged father, mother and child, but the use of Y-chromosomal STR has gained interest in the last few years. In this work, we propose a new probabilistic approach that combines autosomal and Y-chromosomal STR data in paternity testing with father/son pairs taking into account mutation events. We also suggest a new two-stage approach where we first type Y-STRs and possibly autosomal STR for the putative father and son, conditional on Y-STR results. We applied this approach to 22 cases. Our results show that Y-STRs can identify nonpaternity cases with high accuracy but need to be validated with autosomal STR to establish paternity. Moreover, the two-stage approach is less costly than the standard approach and is very useful in motherless cases.  相似文献   
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Buprenorphine, commonly known by the trademark Temgesic, is one of the most popular drugs of abuse among the opioid-addicted young individuals in Iran. Temgesic, Bungesic, etc. are the most popular and important illicit opioid drugs in Tehran's illicit drugs black market, and are now among the most widely abused by opioid addicts. Because of this, counterfeiting of this drug has increased in Tehran. In this study, the qualitative analysis of counterfeit buprenorphine by gas chromatography-mass spectrometry (GC-MS) and high performance liquid chromatography (HPLC) demonstrates the presence of diacetylmorphine, acetylcodeine and pheniramine, as well as the absence of buprenorphine. In conclusion, due to the absence of quality control and difficulties in differentiating counterfeit buprenorphine from genuine products, the use of counterfeit buprenorphine leads the opioid abusers to health risks.  相似文献   
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Leila Zakhirova 《欧亚研究》2013,65(10):1994-2013
The article examines the international politics of water security in Central Asia with a particular focus on the level of regionalism. Are the five Central Asian states evolving into a region capable of solving water management problems on a regional basis? To examine the extent to which water has shaped the structure of Central Asian relations, I use water-related events. The empirical findings suggest that international relations of the Central Asian states are characterised by at least two sets of triads rather than a singular region. The presence of regional fragmentation is likely to exacerbate existing disputes over water and possibly destabilise the region.  相似文献   
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Journal of Family Violence - Survivors of domestic violence (DV) have a wide range of needs when they seek help from DV programs. While there is growing evidence that advocacy and other supportive...  相似文献   
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The aim of this article is to critically interrogate articulations of environmental citizenship in contemporary Turkey. Specifically, I analyse articulations of environmental citizenship through citizen and activist narratives taken from interviews and focus group discussions. I argue that first, scalar focus on local spaces and individuated responsibility for action that emerge from the narratives are crucial to understand future environmental politics and possibilities in this context. Invoking recent discussions related to the politics and performativities of scale, in particular, allows consideration of the politics of visibility and other consequences of these scalar foci. Second, themes from narrative analysis show key convergences with Europeanization- and neoliberalization-related discourses and shifts. The resonance and overlap between these discourses and practices is significant, particularly as it shows citizen receptivity towards broader ideas related to increased citizen responsibility. As such, the research contributes to efforts to move away from theorization of processes such as neoliberalism as top-down, instead enabling examination of ways that these ideals are taken up, expressed, and refashioned by everyday citizens. The third argument that emerges from the analysis, following from the first two, is the need to theorize power more fully in discussions of environmental citizenship. Bridging with neoliberalism discussions is one possible way to move such a project forward.  相似文献   
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