Role behavior of U S . city managers: development and testing of a multidimensional typology

The article addresses a deficiency in previous studies of city managers role behavior: the lack of a comprehensive, multidimensional typology through which such behavior might be categorized and explained. Utilizing factor scores generated from a list of fifteen questions in an I.C.M.A. survey questionnaire, the author uses a hierarchial grouping technique to produce seven profiles of managers role behavior. Personal, environmental, and attitudinal correlates are examined to round out each profile.     

Who’s Socialising Whom? Regional Organisations and Contested Norms in Central Asia

The Organization for Security and Cooperation in Europe (OSCE) and the Shanghai Cooperation Organisation (SCO) represent competing sets of international norms in Central Asia. The contestation between these sets of norms has not led to a complete polarisation between members of the two organisations, however. Instead, the OSCE has used a range of discursive tactics to reduce political contestation, downplaying some contested issues and seeking shared discourses on security threats. This article explores these tactics and suggests that these discursive shifts may eventually threaten the normative identity of the OSCE and lead to the acceptance of a more hybrid set of security-related norms in the region.     

Comparative Analysis of the HV1 and HV2 Regions of Human Mitochondrial DNA by Denaturing High-Performance Liquid Chromatography

Abstract:  Denaturing high-performance liquid chromatography (DHPLC) was evaluated as a sequencing-independent means of detecting the presence of sequence differences in pair-wise mixtures of nonconcordant amplicons of human mitochondrial DNA (mtDNA). A total of 920 pair-wise combinations of HV1 and HV2 mtDNA amplicons from 95 individuals were assayed by DHPLC for sequence concordance/nonconcordance. For the 72 combinations of amplicons from different individuals who shared identical DNA sequences, DHPLC assays consistently indicated sequence concordance between the samples. This was in 100% agreement with sequencing data. For the 849 combinations of amplicons which differed in sequence, DHPLC detected the presence of sequence nonconcordance in all but 13 assays to yield 98.5% concordance with sequencing. Thus, DHPLC can be used to detect a diversity of sequence differences (transitions, transversions, insertions, and deletions) in the mtDNA D-loop. Accordingly, DHPLC may have utility as a presumptive indicator of mtDNA sequence concordance samples, as a screen for heteroplasmy/situational mixtures, and as a means for the physical fractionation of the individual contributors to an mtDNA mixture prior to sequencing.