Identification of furosemide in hair in a post‐mortem case by UHPLC‐MS/MS with guidance on interpretation

Testing for drugs in hair raises several difficulties. Among them is the interpretation of the final concentration(s). In a post‐mortem case, analyses revealed the presence of furosemide (12 ng/mL) in femoral blood, although it was not part of the victim's treatment. The prosecutor requested our laboratory to undertake an additional analysis in hair to obtain information about the use of furosemide. A specific method was therefore developed and validated to identify and quantify furosemide in hair by UHPLC‐MS/MS. After decontamination of 30 mg of hair, incubation in acidic condition, extraction with ethyl acetate, the samples were analyzed by UHPLC‐MS/MS. Furosemide was found in the victim's hair at 225 pg/mg. However, it was not possible to interpret this concentration due to the absence of data in the literature. Therefore, the authors performed a controlled study in two parts. In order to establish the basis of interpretation, several volunteers were tested (four after a single 20 mg administration and twenty‐four under daily treatment). The first part indicated that a single dose is not detectable in hair using our method. The second part demonstrated concentrations ranging from 5 to 1110 pg/mg with no correlation between dosage and hair concentrations. The decedent's hair result was interpreted as repeated exposures. In the case of furosemide analysis, hair can provide information about its presence but cannot give information about dosage or frequency of use.     

Policing Soviet Society: The Evolution of State Control

The Soviet militsiia (regular police) has evolved in the past 70 years from a feeble body seeking to ensure the survival of Soviet rule to a massive bureaucracy corrupted by nearly absolute power. As the Soviet militia has developed the focus of its activities, its ethos, professionalism, and its relationship to both the Party and KGB have changed in all periods, the militia has had political, economic, and social responsibilities, but the balance among the three has wed depending on the conditions of the state.
The militia, like the Soviet state, is currently in crisis. It remains an instrument of the party that is losing its legitimacy among the population. Perestroika's objective of making institutions subordinate to the law is a sharp deviation from existing practice. But even if the militsiia responds to these new expectations, because of the demands of a centrally planned socialist state the regular police will remain we intrusive into the lives of the citizenry than are police in Western democratic societies.     

Type and Severity of Abuse as Predictors of Psychiatric Symptoms in Adolescence

There has been little previous research about histories of child maltreatment and psychological symptoms in adolescent psychiatric patients. This study investigated whether type and characteristics of child physical and/or sexual abuse predicted individual differences in symptoms. Participants were 187 patients in day or residential treatment facilities. Abuse was assessed using structured interviews with the adolescent, the therapist, and the caseworker. Participants completed a standardized, self-report measure of internalizing and externalizing symptoms. Adolescents with histories of dual abuse (i.e., sexual and physical abuse) had elevated depression and anxiety compared with nonabused patients. Histories of any type of abuse were associated with elevated posttraumatic symptoms. Among physically abused patients, severity and duration of abuse predicted individual differences in depression and anxiety, whereas severity and concomitant sexual abuse predicted elevated posttraumatic symptoms. Among sexually abused patients, the characteristics of sexual abuse did not predict individual differences in symptoms. Thus, child abuse, particularly dual abuse and severe physical abuse, predicted elevated internalizing symptoms, even in comparison with other adolescent psychiatric patients. The need for replication is discussed.     

Urban community organizations and local government: Exploring relationships and roles

There is an increasing interest in using local community organizations to assist in the development process. Observers who evaluate the contribution of such groups frequently classify them into two clusters: those which are closely tied to the government and focus on service delivery, and those which guard their autonomy and engage in development rather than service delivery. This dichotomy, however, downplays the developmental role of groups allied with local governments and obscures some important contributions they can offer. Three different models are proposed and two case studies of service-oriented groups in Cairo are presented. The cases suggest that an important criterion in assessing voluntary groups is the extent to which their service delivery role enables them to develop an organization. From this perspective their role is potentially much broader than expediting government services.     

La coopération à I'intérieur d'une région métropolitaine: éléments d'analysey†

Sommaire. Les relations inter-municipales, à l'intérieur d;une région métropolitaine, sont abordées dam cet article sous l'angle de la coopération qu'elles impliquent. L'auteur fait un tour d'horizon des principaux concepts qui sont utilisés dans l'étude de la coopération et de l'intégration, à l'aide des nombreux travaux publiées sur le sujet. Après avoir défini l'intégration, l'auteur précise les différentes modalités d'intégration, ainsi que les conditions favorables et les avantages de l'intégration au niveau municipal. Abstract. This article focuses on the relationship between municipalities within a regional area, from the point of view of the cooperation they imply. The author reviews the major concepts utilized in the study of cooperation and integration, using research material already published. The concept of integration is defined in the first part, followed by a review of the different modalities of integration and of the conditions to and advantages of integration at the municipal level.     

The rise of Femi‐Nazis? Female participation in right‐extremist movements in unified Germany

German feminist scholars have recently come to argue that female involvement in right‐extremist causes is grounded in gender‐specific motives. They have also begun to uncover a troubling link between new patterns of female political engagement (ranging from electoral mobilisation to violent streetfighting) and their own efforts to promote an independent women's consciousness since the 1960s. This article develops a typology of New Right women, characterised here as Femi‐Nazis, evincing different levels of sympathy for, identification with, and participation in radical and extremist movements. It then explores five issue orientations distinguishing New Right women of the 1990s from the Old and New Right men of the 1940s and 1990s, suggesting that these women have developed an independent, self‐assertive political consciousness without internalising feminism's broader aims of diversity and inclusion. The article concludes with reflections on the interplay of ‘feminist’ consciousness and ultra‐nationalist qua xenophobic attitudes, and on the dilemmas Femi‐Nazi thinking poses for feminist identity in united Germany.     

Building metropolitan governance capacity: The case of the Communauté métropolitaine de Montréal

Abstract: This article is about building metropolitan governance capacity. Based on the case study of the Communauté métropolitaine de Montréal (the Montreal Metropolitan Community), the authors seek to understand how this new metropolitan institution develops its capacity to manage metropolitan issues. What factors influence metropolitan governance capacity? What are the impacts of actor behaviour, incentive structures, and political leadership on that capacity? Specifically, results focus on two of the CMM's areas of responsibility: land‐use planning, and social and affordable housing. Based on the analysis of official documents of the CMM (its act of incorporation, activity reports, budget, etc.) and thirteen interviews with elected municipal officials and public servants, the authors show that the building of metropolitan governance capacity is influenced by the interactions between those three factors, as well as by other elements specific to each context.