汉族人群五个STR基因座的多态性调查

应用PCR及PAG电泳技术研究了PLA2A、vWA、CYP19、TH和LPL五个基因座的多态性，调查武汉地区汉族无关个体，获得汉族人群的频率分布。五个基因座基因型频率分布与Hardy-Weinberg平衡吻合良好、分别计算基因座的杂合度（H）、个人识别能力（Dp）、非父排除率（PE）和多态性信息总量（PIC）。为法医学应用提供了基础数据。     

Emerging Liabilities from Pharmaceuticals and Personal Care Products

There is growing awareness and concern regarding the presence of chemical constituents of pharmaceuticals and personal care products (“PPCPs”) in the environment. A recent USGS study indicated that PPCPs are present at low levels in surface water throughout the U.S. Concern is based in part on the fact that certain PPCPs: (1) are designed to have biological effects (particularly pharmaceuticals), (2) are persistent in or continually added to the environment, (3) have negative environmental effects (specifically on aquatic life) even at low levels, and (4) potentially have cumulative and synergistic effects when combined with other PPCPs. The primary route of PPCPs into the environment is sewage discharges, septic systems, and large stock yards and feedlots where the unmetabolized PPCPs are excreted by humans and animals and end up in surface water and ground-water. Given these circumstances, manufacturers of PPCPs may face a risk of increased regulation and possibly litigation similar to that faced by oxygenate manufacturers and petroleum refiners over the use of Methyl Tertiary Butyl Ether (“MTBE”). Companies can take steps now and in the future that may minimize the impact of these risks.     

Fear of victimization and health

Fear of victimization may have consequences for subjective well-being. I develop and test a model linking fear of victimization to subjective health. I hypothesize that two processes link fear to subjective health-psychological and behavioral. Specifically, I hypothesize that fear of victimization increases psychological distress, and fear decreases outdoor physical activity, especially walking. High levels of psychological distress and low levels of walking, in turn, are associated with poor self-reported health. I find empirical support for the hypothesized processes in a representative national sample of 2031 adults aged 18 to 90 interviewed by telephone in 1990. The negative association between fear and health is explained largely by psychological distress and walking. However, a significant direct effect remains. I conclude with suggestions for future research linking crime and health, focusing on the need for collecting information on community disorganization. Community context is likely the ultimate exogenous variable-the one that sets in motion the destructive cycle of fear, distress, inactivity, and poor health described here.