Publications received

Publications Received

Publications received     

Duplications of the Y-chromosome specific loci P25 and 92R7 and forensic implications

In the present study, we demonstrate that two commonly used Y-chromosome single nucleotide polymorphisms (SNPs), P25 and 92R7, are paralogous sequence variants (PSVs) originating from segmental duplications and that at least one of the sequence variants in each group of loci is polymorphic. Several methodologies were used in order to detect the SNP alleles and the PSVs of the loci. All results obtained with the various typing techniques supported the conclusion. The allele distributions of the binary markers were analysed in more than 600 males with seven different haplogroups. For P25, the ancestral allele C was found in several samples from different haplogroups. The derived allele A was always present with an additional C variant. Haplogroup P was defined by the derived allele A at the 92R7 locus. However, the ancestral allele G was always associated with an A variant due to the duplication.     

‘Why do we need all this?’ A call against genetic engineering and reproductive technology

The central argument of this article is that the discussion on the new reproduction technology should not start with these technologies as such and their possible benefits and abuses but with the basic question whether we need this technology at all, whether the fundamental problems of women in capitalist-patriarchal societies can be solved by technology. According to the author, genetic engineering and reproductive technology are not only not capable of solving any of these questions, they are destructive to a human relation to our bodies, nature, other peoples. Exploitative and oppressive relations cannot be overcome by more sophisticated technology-even if it were in the hands of women—but only by a revolutionizing of these relations.     

Federal laboratory missions,products, and competitiveness

A number of initiatives over the past decade have tried to increase the federal laboratory system's impact on U.S. competitiveness, largely based on assumptions that the system is a reservoir of readily available technology appropriate to industry's competitive needs. However, there is a virtual absence of empirical data on the nature of research and development in the national laboratory system and the character of its R&D “products.” This paper reviews the limited data on R&D in the national laboratory system available from the General Accounting Office, the National Science Foundation, and the National Comparative Research and Development Project. The findings suggest that technologies available within the system are likely to emerge from the most strongly mission-oriented R&D, and are therefore the least likely to spin off and diffuse throughout the industrial base. Once the hardware needs of the Department of Defense (DOD), the Department of Energy (DOE), and the National Aeronautics and Space Administration (NASA) are excluded, most of the system's R&D output is fundamental knowledge, which flows through public domain literature and requires substantial additional processing to become commercial products. The implications are (1) there is no reason to believe the current federal laboratory system can directly enhance U.S. competitiveness; (2) in order for labs to contribute to competitiveness, they must have more explicit missions to do so; and (3) policy expectations of commercial impacts are inconsistent with policy requirements that labs conduct precommercial basic and applied research.     

Visualization of bridging veins by means of postmortem computed tomography

At autopsy, visualization of lesions of the bridging veins, a frequent source of subdural bleeding, is difficult due to their anatomical localization. On the other hand their demonstration is of great importance for the assignment to a chronologically defined trauma. For this reason a postmortem method using computed tomography was developed to visualize the intracranial venous system by means of X-ray contrast media. In subdural bleedings, in which the skull had not been opened up, ruptured vessels could be accurately localized with this method, so that targeted dissection was possible during the subsequent autopsy.