Identification of furosemide in hair in a post‐mortem case by UHPLC‐MS/MS with guidance on interpretation

Testing for drugs in hair raises several difficulties. Among them is the interpretation of the final concentration(s). In a post‐mortem case, analyses revealed the presence of furosemide (12 ng/mL) in femoral blood, although it was not part of the victim's treatment. The prosecutor requested our laboratory to undertake an additional analysis in hair to obtain information about the use of furosemide. A specific method was therefore developed and validated to identify and quantify furosemide in hair by UHPLC‐MS/MS. After decontamination of 30 mg of hair, incubation in acidic condition, extraction with ethyl acetate, the samples were analyzed by UHPLC‐MS/MS. Furosemide was found in the victim's hair at 225 pg/mg. However, it was not possible to interpret this concentration due to the absence of data in the literature. Therefore, the authors performed a controlled study in two parts. In order to establish the basis of interpretation, several volunteers were tested (four after a single 20 mg administration and twenty‐four under daily treatment). The first part indicated that a single dose is not detectable in hair using our method. The second part demonstrated concentrations ranging from 5 to 1110 pg/mg with no correlation between dosage and hair concentrations. The decedent's hair result was interpreted as repeated exposures. In the case of furosemide analysis, hair can provide information about its presence but cannot give information about dosage or frequency of use.     

The rise of Femi‐Nazis? Female participation in right‐extremist movements in unified Germany

German feminist scholars have recently come to argue that female involvement in right‐extremist causes is grounded in gender‐specific motives. They have also begun to uncover a troubling link between new patterns of female political engagement (ranging from electoral mobilisation to violent streetfighting) and their own efforts to promote an independent women's consciousness since the 1960s. This article develops a typology of New Right women, characterised here as Femi‐Nazis, evincing different levels of sympathy for, identification with, and participation in radical and extremist movements. It then explores five issue orientations distinguishing New Right women of the 1990s from the Old and New Right men of the 1940s and 1990s, suggesting that these women have developed an independent, self‐assertive political consciousness without internalising feminism's broader aims of diversity and inclusion. The article concludes with reflections on the interplay of ‘feminist’ consciousness and ultra‐nationalist qua xenophobic attitudes, and on the dilemmas Femi‐Nazi thinking poses for feminist identity in united Germany.     

Building metropolitan governance capacity: The case of the Communauté métropolitaine de Montréal

Abstract: This article is about building metropolitan governance capacity. Based on the case study of the Communauté métropolitaine de Montréal (the Montreal Metropolitan Community), the authors seek to understand how this new metropolitan institution develops its capacity to manage metropolitan issues. What factors influence metropolitan governance capacity? What are the impacts of actor behaviour, incentive structures, and political leadership on that capacity? Specifically, results focus on two of the CMM's areas of responsibility: land‐use planning, and social and affordable housing. Based on the analysis of official documents of the CMM (its act of incorporation, activity reports, budget, etc.) and thirteen interviews with elected municipal officials and public servants, the authors show that the building of metropolitan governance capacity is influenced by the interactions between those three factors, as well as by other elements specific to each context.     

The Role of Body Image in Women's Mental Health

This article was inspired by the Body Image Summit on 21 June 2000 in London at which a panel, headed by Tessa Jowell, Minister for Women, led a discussion among representatives of the media and British fashion industry. The aims of the Summit were to consider the effects of advertising images on teenage girls and women and to develop a consensus from within these industries to incorporate a social and ethical awareness in their promotional activities. A negative reaction to this forum was the main result. In this article I offer both a sociological and psychoanalytically based discussion of the problem of body image for women. I also consider how society and women themselves could begin to counteract the pernicious effects of being sold unrealistically thin, ideal images of womanhood continually perpetrated by consumerism.     

Access to information: An asset for democracy or ammunition for political conflict,or both?

More than twenty‐five years after its adoption, the Access to Information Act has become increasingly a cause for concern among public servants, experts, scientists and the media. This article reviews the evolution of the access‐to‐information regime since the 1980s, the issues that have arisen, the political significance of information in democracy, and the enduring tension between its democratic purpose and strategic value. The article also examines the issues of centralization, control and secrecy within the state apparatus despite continuing calls for transparency. Under Conservative governments since 2006, there has been increased control and conflict over disclosure of information, which have spread to a larger part of the state apparatus. Among those involved in conflicts over information with the Prime Minister's Office are members and officers of Parliament and parliamentary committees.